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Leif Bergsagel, MD PhD
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Journal Articles

The Mutational and Signaling Landscape of Multiple Myeloma Varies Dependent upon Translocation Cyclin D (TC) Subgroup

Caleb K. Stein, MS, Charlotte Pawlyn, MB BChir, Shweta S. Chavan, PhD, Niels Weinhold, PhD, Brian A Walker, PhD, Adam Rosenthal, Ola Landgren, MD, PhD, Peter Leif Bergsagel, MD PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4441.
https://doi.org/10.1182/blood.V128.22.4441.4441
Published: 2016
Journal Articles

Targeted Sequencing of Relapsed/Refractory Myeloma Patients Identifies an Enrichment of Mutations in Cereblon and MAPK Pathways

Elias Karl Mai, MD, K. Martin Kortuem, MD, Nur Hanafiah, Santiago Barrio, Laura Ann Bruins, Maximilian Merz, MD, Jing Xu, Koenuel Pashayeva, MD, Yuan-Xiao Zhu, Chang-Xin Shi, PhD, R. Alexander Stewart, Patrick Jedlowski, Mindaugas Andrulis, MD, Anna Jauch, Prof., Jens Hillengass, MD, Hartmut Goldschmidt, MD, P. Leif Bergsagel, MD PhD, Esteban Braggio, PhD, A. Keith Stewart, MD, Marc Steffen Raab, MD PhD
Journal: Blood
Blood (2015) 126 (23): 723.
https://doi.org/10.1182/blood.V126.23.723.723
Published: 2015
Journal Articles

UCHL1 Is a Biomarker of Aggressive Multiple Myeloma Required for Disease Progression

Sajjad Hussain, PhD, Tibor Bedekovics, PhD, Marta Chesi, PhD, Leif Bergsagel, MD PhD, Paul J. Galardy, MD
Journal: Blood
Blood (2015) 126 (23): 2980.
https://doi.org/10.1182/blood.V126.23.2980.2980
Published: 2015
Journal Articles

Immunomodulatory Drugs Inhibit H 2 O 2 Decomposition in Multiple Myeloma Cells and Its Mediated Cytotoxicity Is Determined By Cellular Antioxidative Capacity

Sinto Sebastian Chirackal, PhD, Yuan Xiao Zhu, PhD, Esteban Braggio, PhD, Chang-Xin Shi, PhD, Sonali Panchabhai, MBBS, Gregory Ahmann, BS, Scott A. Van Wier, BS, Marta Chesi, PhD, Leif Bergsagel, MD PhD, Keith Stewart, MD, Rafael Fonseca, MD
Journal: Blood
Blood (2015) 126 (23): 2475.
https://doi.org/10.1182/blood.V126.23.2475.2475
Published: 2015
Journal Articles

Ikaros-Dependent Downregulation of MYC with IMiDs in Myeloma (MM) Cells Is Mediated through the Depletion of the Acetylated Chromatin Reader BRD4 at Super-Enhancer Loci

Paola Neri, MD PhD, Ines Tagoug, PhD, Justin Simms, Ranjan Maity, PhD, Jacquelyn Babich, Victor Jimenez-Zepeda, MD, Peter Duggan, MD, Fariborz Kolvear, PhD, Jonathan J Keats, PhD, Leif Bergsagel, MD PhD, Nizar J Bahlis, MD
Journal: Blood
Blood (2015) 126 (23): 4175.
https://doi.org/10.1182/blood.V126.23.4175.4175
Published: 2015
Journal Articles

Characterization of the Role of Regulatory T Cells (Tregs) in Inducing Progression of Multiple Myeloma

Yawara Kawano, MDPhD, Michele Moschetta, MD, Katsutoshi Kokubun, PhD, Pavlo Lukyanchykov, MD, Esilida Sula Karreci, MD, Salomon Manier, MD, Shokichi Tsukamoto, MD PhD, Satoshi Takagi, PhD, Jiantao Shi, Michaela R. Reagan, PhD, Daisy Huynh, BS, MS, Antonio Sacco, BS, David M. Dorfman, MD PhD, Marta Chesi, PhD, Peter Leif Bergsagel, MD PhD, Aldo M Roccaro, MD PhD, Jamil Azzi, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2015) 126 (23): 502.
https://doi.org/10.1182/blood.V126.23.502.502
Published: 2015
Journal Articles

Angiogenesis Associated with Alterations of the Bone Marrow Microenvironment Predicts Multiple Myeloma Progression to Symptomatic Disease in Mice and Humans

Arianna Calcinotto, Maurilio Ponzoni, Roberto Ria, Matteo Grioni, Elena Cattaneo, Isabella Villa, Maria Teresa Sabrina Bertilaccio, Marta Chesi, PhD, Alessandro Rubinacci, Giovanni Tonon, MDPhD, Peter Leif Bergsagel, MD PhD, Angelo Vacca, MD PhD, Matteo Bellone, MD
Journal: Blood
Blood (2014) 124 (21): 5678.
https://doi.org/10.1182/blood.V124.21.5678.5678
Published: 2014
Journal Articles

Early Trafficking of Bone Marrow Derived-Endothelial Progenitor Cells Promotes Multiple Myeloma Progression

Michele Moschetta, MD, Yuji Mishima, PhD, Yawara Kawano, MD PhD, Yosra Aljawai, MS, Bruno Paiva, PhD, Luis Palomera, MD, Arianna Calcinotto, Unitt L. Christine, BSc, Ilyas Sahin, MD, Antonio Sacco, BS, Siobhan Glavey, MD, Michaela R. Reagan, PhD, Salomon Manier, MD, Peter Leif Bergsagel, MD PhD, Marta Chesi, PhD, Matteo Bellone, MD, Aldo M Roccaro, MD PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2014) 124 (21): 4719.
https://doi.org/10.1182/blood.V124.21.4719.4719
Published: 2014
Journal Articles

p90RSK2 as a Therapeutic Target in Treatment of FGFR3-Expressing t(4;14) Multiple Myeloma.

Sumin Kang, PhD, Shaozhong Dong, PhD, Tinglei Gu, PhD, Ailan Guo, PhD, Michael S. Cohen, PhD, Sagar Lonial, MD, PhD, Petet Leif Bergsagel, MD, PhD, Jack Taunton, PhD, Roberto D. Polakiewicz, PhD, Jing Chen, PhD
Journal: Blood
Blood (2007) 110 (11): 253.
https://doi.org/10.1182/blood.V110.11.253.253
Published: 2007