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Journal Articles

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Alison R. Moliterno, MD, Donna Marie Williams, PhD, Liping Li, MD PhD, Lingling Xian, MD PhD, Li Luo, PhD, Amy S. Duffield, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 472.

https://doi.org/10.1182/blood-2019-131432

Published: 2019

Journal Articles

Use of Pegylated Interferon in Six Pediatric Patients with Myeloproliferative Neoplasms

Nicole Kucine, MD, Shayla Bergmann, MD, Spencer Krichevsky, BS, Devin Jones, MS, Michael E. Rytting, MD, Linda Resar, MD, John Mascarenhas, MD, Srdan Verstovsek, MD PhD, Ronald Hoffman, MD

Blood (2019) 134 (Supplement_1): 4194.

https://doi.org/10.1182/blood-2019-124023

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Liping Li, MD PhD, Katharina Hayer, Lingling Xian, MD PhD, Li Luo, PhD, Leslie Cope, Andrei Thomas-Tikhonenko, PhD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 3946.

https://doi.org/10.1182/blood-2019-130261

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Liping Li, MD PhD, Wenyan Lu, PhD, Alison R. Moliterno, MD, Lingling Xian, MD PhD, Joseph Kim, BS, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 1680.

https://doi.org/10.1182/blood-2019-130262

Published: 2019

Journal Articles

Worse Outcomes in Males with MPN Are Associated with Qualitative and Quantitative Differences in Non-Driver Mutational Burden

Theodoros Karantanos, MD PhD, Evan M Braunstein, MD PhD, Shruti Chaturvedi, MBBS, MS, Jerry L. Spivak, MD, Linda Resar, MD, Styliani Karanika, MD, Donna Marie Williams, PhD, Christopher D Gocke, MD, Alison R. Moliterno, MD

Blood (2019) 134 (Supplement_1): 837.

https://doi.org/10.1182/blood-2019-125393

Published: 2019

Journal Articles

Independent Association of Male Sex with Presentation and Clinical Outcomes in Myeloproliferative Neoplasms

Theodoros Karantanos, MDPhD, Shruti Chaturvedi, MBBS,MS, Jerry L. Spivak, MD, Linda Resar, MD, Evan M Braunstein, MDPhD, Styliani Karanika, MD, Donna Marie Williams, PhD, Ophelia Rogers, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 1768.

https://doi.org/10.1182/blood-2018-99-112683

Published: 2018

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Wenyan Lu, PhD, Briyana Chisholm, BS, Li Luo, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 102.

https://doi.org/10.1182/blood-2018-99-119549

Published: 2018

Journal Articles

Myeloproliferative Neoplasms in Pediatrics and Young Adults: Genetic Lesions, Diagnostic Features, and Clinical Outcomes

Linda Resar, MD, Donna Marie Williams, PhD, Evan M Braunstein, MDPhD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 4180.

https://doi.org/10.1182/blood.V130.Suppl_1.4180.4180

Published: 2017

Journal Articles

Germline ERBB2 Variants Associate with Myeloproliferative Neoplasms

Evan M Braunstein, MDPhD, Donna Marie Williams, PhD, Igor Makhlin, MD, Aparna Pallavajjala, Christopher D Gocke, MD, Nara Sobreira, MD, Kala Visvanathan, MD, Linda Resar, MD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 1663.

https://doi.org/10.1182/blood.V130.Suppl_1.1663.1663

Published: 2017

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 489.

https://doi.org/10.1182/blood.V130.Suppl_1.489.489

Published: 2017

Journal Articles

High Mobility Group A1 Chromatin Remodeling Protein Regulates Self-Renewal, Niche Formation, and Regenerative Function in Adult Stem Cells through Wnt/β-Catenin Signaling

Linda Resar, MD, Lingling Xian, MD PhD, Tait Huso, Amy Belton, PhDBSc, Leslie Cope, PhDBSc, David Huso, DVM, PhD

Blood (2016) 128 (22): 2647.

https://doi.org/10.1182/blood.V128.22.2647.2647

Published: 2016

Journal Articles

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

Linda Resar, MD, Donna Marie Williams, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Lingling Xian, MD PhD, Jerry L. Spivak, MD, Alison R Moliterno, MD

Blood (2016) 128 (22): 1958.

https://doi.org/10.1182/blood.V128.22.1958.1958

Published: 2016

Journal Articles

A Novel Feed-Forward Loop Involving the High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein and cMYC in Acute Myeloid Leukemia Is Targeted By JQ1

Linda Resar, MD, Stuart A Rushworth, PhDBSc, Lingling Xian, MD PhD, Kristian Bowles, MB BS, PhD FRCP, FRCPath

Blood (2015) 126 (23): 2466.

https://doi.org/10.1182/blood.V126.23.2466.2466

Published: 2015

Journal Articles

HMGA1 Drives Inflammatory Pathways, Cell Cycle Progression, and Embryonic Stem Cell Genes During Leukemic Transformation

Andrew Schuldenfrei, Amy Belton, Ph.D., Jeanne Kowalski, PhD, C. Conover Talbot, Jr., B.S., Francescopaolo Di Cello, Weijie Poh, Hua-Ling Tsai, MS, Sandeep N Shah, Tait Huso, David Huso, D.V.M., Ph.D., Linda Resar, MD

Blood (2011) 118 (21): 1371.

https://doi.org/10.1182/blood.V118.21.1371.1371

Published: 2011

Journal Articles

Inactivation of the INK4A/ARF ( CDKN2 ) locus Cooperates with HMGA1 in T-Cell Leukemogenesis.

Linda Resar, MD, Francescopaolo Di Cello, Ph.D., Surajit Dhara, Ph.D., Jeanne Kowalski, Ph.D., Ossama Elbahlouh, M.D., Joelle Hillion, Ph.D., Stuart Winter, MD, Richard S. Larson, MD, PhD, David Huso, D.V.M., Ph.D.

Blood (2009) 114 (22): 3969.

https://doi.org/10.1182/blood.V114.22.3969.3969

Published: 2009

Journal Articles

The HMGA1a-STAT3 axis: an “Achilles Heel” for Hematopoietic Malignancies Overexpressing HMGA1a?

Linda Resar, MD, Joelle Hillion, Ph.D., Surajit Dhara, Ph.D., Takita Felder Sumter, Ph.D., Mita Mukherjee, Ph.D., Francescopaolo Di Cello, Ph.D., Amy Belton, Ph.D., James Turkson, Ph.D., Souyma Jaganathan, Ph.D., Linzhao Cheng, Ph.D., Zhaohui Ye, B.S., Yingwei Lin, MD, PhD, Peter D. Aplan, MD, Richard Jove, Jeanne Kowalski, Kelsey Wertzler, B.S., Ray Reeves, Ph.D., Ossama Elbahlouh, M.D., Raka Bhattacharya, Ph.D.

Blood (2008) 112 (11): 3810.

https://doi.org/10.1182/blood.V112.11.3810.3810

Published: 2008

Journal Articles

STAT3: A Direct HMGA1 Gene Target Important in Lymphoid Malignancy.

Linda Resar, MD, Surajit Dhara, Ph.D., Takita Felder Sumter, Ph.D., Mita Mukherjee, Ph.D., James Turkson, Ph.D., Rich Jove, Ph.D., Ossama Elbahloul, M.D., Peter Aplan, M.D., Ying-Wei Lin, M.D., Ph.D., Raka Bhattacharya, Ph.D.

Blood (2006) 108 (11): 2222.

https://doi.org/10.1182/blood.V108.11.2222.2222

Published: 2006

NARROW

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Use of Pegylated Interferon in Six Pediatric Patients with Myeloproliferative Neoplasms

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Worse Outcomes in Males with MPN Are Associated with Qualitative and Quantitative Differences in Non-Driver Mutational Burden

Independent Association of Male Sex with Presentation and Clinical Outcomes in Myeloproliferative Neoplasms

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Myeloproliferative Neoplasms in Pediatrics and Young Adults: Genetic Lesions, Diagnostic Features, and Clinical Outcomes

Germline ERBB2 Variants Associate with Myeloproliferative Neoplasms

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

High Mobility Group A1 Chromatin Remodeling Protein Regulates Self-Renewal, Niche Formation, and Regenerative Function in Adult Stem Cells through Wnt/β-Catenin Signaling

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

A Novel Feed-Forward Loop Involving the High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein and cMYC in Acute Myeloid Leukemia Is Targeted By JQ1

HMGA1 Drives Inflammatory Pathways, Cell Cycle Progression, and Embryonic Stem Cell Genes During Leukemic Transformation

Inactivation of the INK4A/ARF ( CDKN2 ) locus Cooperates with HMGA1 in T-Cell Leukemogenesis.

The HMGA1a-STAT3 axis: an “Achilles Heel” for Hematopoietic Malignancies Overexpressing HMGA1a?

STAT3: A Direct HMGA1 Gene Target Important in Lymphoid Malignancy.

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American Society of Hematology

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American Society of Hematology

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