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Lora B Kramer
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Journal Articles

Bcl-2 Antagonism Potentiates MEK1/2/Chk1 Inhibitor Lethality in Multiple Myeloma Cells Overexpressing Bcl-2 through a Stat3-Dependent Mechanism

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Xin-Yan Pei, MD, Michael W Sanderson, BS, Leena E Youssefian, M.S, Jessica Felthousen, BS, Lora B Kramer, BS, Yun Dai, PhD, Steven Grant, MD
Journal: Blood
Blood (2014) 124 (21): 4763.
https://doi.org/10.1182/blood.V124.21.4763.4763
Published: 2014
Journal Articles

Cytokinetically quiescent (G 0 /G 1 ) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2

Free
Xin-Yan Pei, Yun Dai, Leena E. Youssefian, Shuang Chen, Wesley W. Bodie, Yukie Takabatake, Jessica Felthousen, Jorge A. Almenara, Lora B. Kramer, Paul Dent, Steven Grant
Journal: Blood
Blood (2011) 118 (19): 5189–5200.
https://doi.org/10.1182/blood-2011-02-339432
Published: 2011
Includes: Supplemental data
Journal Articles

Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo

Free
Yun Dai, Shuang Chen, Rena Shah, Xin-Yan Pei, Li Wang, Jorge A. Almenara, Lora B. Kramer, Paul Dent, Steven Grant
Journal: Blood
Blood (2011) 117 (6): 1947–1957.
https://doi.org/10.1182/blood-2010-06-291146
Published: 2011
Includes: Supplemental data
Journal Articles

Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor–induced DNA damage in vitro and in vivo in human multiple myeloma cells

Free
Yun Dai, Shuang Chen, Xin-Yan Pei, Jorge A. Almenara, Lora B. Kramer, Charis A. Venditti, Paul Dent, Steven Grant
Journal: Blood
Blood (2008) 112 (6): 2439–2449.
https://doi.org/10.1182/blood-2008-05-159392
Published: 2008
Includes: Supplemental data