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Journal Articles

Triptolide Induces Apoptosis In Acute Lymphoblastic Leukemia Cells by Inhibition of the Oncoprotein MDM2

Mei Huang, Lubing Gu, MD, Muxiang Zhou, MD

Blood (2010) 116 (21): 4934.

https://doi.org/10.1182/blood.V116.21.4934.4934

Published: 2010

Journal Articles

Berberine Induces Apoptosis In Acute Lymphoblastic Leukemia Cells by Demethylation of RASSF1A and Self-Ubiquitination of MDM2.

Jing He, MD, PhD, Hailong Zhang, Jiansha Li, Lubing Gu, MD, Muxiang Zhou, MD

Blood (2010) 116 (21): 3627.

https://doi.org/10.1182/blood.V116.21.3627.3627

Published: 2010

Journal Articles

MDM2 SNP 309 Is Not Associated with Increased Expression Levels of MDM2 Nor Clinical Significance in Childhood Acute Lymphoblastic Leukemia

Jing He, MD, PhD., Lubing Gu, MD, Muxiang Zhou, MD

Blood (2008) 112 (11): 5326.

https://doi.org/10.1182/blood.V112.11.5326.5326

Published: 2008

Journal Articles

Berberine Induces Apoptosis in Acute Lymphoblastic Leukemia Cells through Downregulation of the MDM2 Oncoprotein.

Xiaoling Zhang, Lubing Gu, MD, Noopur Shah, Muxiang Zhou, MD

Blood (2008) 112 (11): 1628.

https://doi.org/10.1182/blood.V112.11.1628.1628

Published: 2008

Journal Articles

The MDM2 Antagonist Nutlin-3 Is a Potent Inducer of Apoptosis in Pediatric Acute Lymphoblastic Leukemia Cells with Wild-Type p53 and Overexpression of MDM2.

Lubing Gu, MD, Ningxi Zhu, MD, PhD, Harry W. Findley, PhD, Muxiang Zhou, MD

Blood (2007) 110 (11): 4277.

https://doi.org/10.1182/blood.V110.11.4277.4277

Published: 2007

Journal Articles

Inhibition of Akt/Survivin Pathway Synergizes the Antileukemia Effect of Nutlin-3 in Acute Lymphoblastic Leukemia Cells.

Ningxi Zhu, MD, PhD, Lubing Gu, MD, Muxiang Zhou, MD

Blood (2007) 110 (11): 2790.

https://doi.org/10.1182/blood.V110.11.2790.2790

Published: 2007

Journal Articles

Targeting CD22 in Childhood B-Precursor Acute Lymphoblastic Leukemia (Pre-B ALL): Pre-Clinical Studies and Phase I Trial of the Anti-CD22 Immunotoxin CAT-3888 (BL22).

Alan S. Wayne, MD, Harry W. Findley, PhD, Glen Lew, MD, Yachna Ahuja, BS, Lubing Gu, MD, Maryalice Stetler-Stevenson, MD, PhD, Robert J. Kreitman, MD, Ira Pastan, MD

Blood (2007) 110 (11): 855.

https://doi.org/10.1182/blood.V110.11.855.855

Published: 2007

Journal Articles

Contribution of STAT3 to Activation of Survivin by Granulocyte-Macrophage Colony-Stimulating Factor in CD34+ Cells.

Lubing Gu, MD, Kuang-Yueh Chiang, MD, Ningxi Zhu, MD,PhD, Harry W. Findley, PhD, Muxiang Zhou, MD

Blood (2006) 108 (11): 4202.

https://doi.org/10.1182/blood.V108.11.4202.4202

Published: 2006

Journal Articles

Expression of Inhibitor-of-Apoptosis Protein (IAP) Livin in Pediatric Acute Lymphoblastic Leukemia (ALL) Cells.

Anindya Dasgupta, PhD, Lubing Gu, MD, Carlos S. Alvarado, MD, Muxiang Zhou, MD, Harry W. Findley, PhD

Blood (2005) 106 (11): 4526.

https://doi.org/10.1182/blood.V106.11.4526.4526

Published: 2005

Journal Articles

Endogenous TNFα Mediates Cell Survival and Chemotherapy Resistance by Activating the PI3K/Akt Pathway in Childhood Acute Lymphoblastic Leukemia.

Lubing Gu, MD, Harry W. Findley, PhD, Ningxi Zhu, MD, PhD, Muxiang Zhou, MD

Blood (2005) 106 (11): 4551.

https://doi.org/10.1182/blood.V106.11.4551.4551

Published: 2005

Journal Articles

Vitamin K3 Selectively Induces Apoptosis in Acute Lymphoblastic Leukemia Cells with Constitutive Activation of IKKα/NF-kB Activation.

Ningxi Zhu, MD, PhD, Lubing Gu, MD, Harry W. Findley, PhD, Kuang-Yueh Chiang, MD, Muxiang Zhou, MD

Blood (2005) 106 (11): 859.

https://doi.org/10.1182/blood.V106.11.859.859

Published: 2005

Journal Articles

Loss of PTEN Expression Induces NF-kB Via PI3K/Akt Pathway Involving Resistance to Chemotherapy in Acute Lymphoblastic Leukemia Cell Lines.

Lubing Gu, MD, Ningxi Zhu, MD, PhD, Harry W. Findley, PhD, Muxiang Zhou, MD

Blood (2004) 104 (11): 4438.

https://doi.org/10.1182/blood.V104.11.4438.4438

Published: 2004

Journal Articles

An Alternatively Spliced Survivin Variant Is Positively Regulated by p53 and Sensitizes Leukemia Cells to Chemotherapy.

Ningxi Zhu, MD, PhD, Lubing Gu, MD, Harry W. Findley, PhD, Fengzhi Li, PhD, Muxiang Zhou, MD

Blood (2004) 104 (11): 3497.

https://doi.org/10.1182/blood.V104.11.3497.3497

Published: 2004

Journal Articles

MDM2 induces NF-κB/p65 expression transcriptionally through Sp1-binding sites: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia

Lubing Gu, Harry W. Findley, Muxiang Zhou

Blood (2002) 99 (9): 3367–3375.

https://doi.org/10.1182/blood.V99.9.3367

Published: 2002

Journal Articles

Expression and Regulation of Bcl-2, Bcl-xl, and Bax Correlate With p53 Status and Sensitivity to Apoptosis in Childhood Acute Lymphoblastic Leukemia

Harry W. Findley, Lubing Gu, Andrew M. Yeager, Muxiang Zhou

Blood (1997) 89 (8): 2986–2993.

https://doi.org/10.1182/blood.V89.8.2986

Published: 1997

NARROW

Triptolide Induces Apoptosis In Acute Lymphoblastic Leukemia Cells by Inhibition of the Oncoprotein MDM2

Berberine Induces Apoptosis In Acute Lymphoblastic Leukemia Cells by Demethylation of RASSF1A and Self-Ubiquitination of MDM2.

MDM2 SNP 309 Is Not Associated with Increased Expression Levels of MDM2 Nor Clinical Significance in Childhood Acute Lymphoblastic Leukemia

Berberine Induces Apoptosis in Acute Lymphoblastic Leukemia Cells through Downregulation of the MDM2 Oncoprotein.

The MDM2 Antagonist Nutlin-3 Is a Potent Inducer of Apoptosis in Pediatric Acute Lymphoblastic Leukemia Cells with Wild-Type p53 and Overexpression of MDM2.

Inhibition of Akt/Survivin Pathway Synergizes the Antileukemia Effect of Nutlin-3 in Acute Lymphoblastic Leukemia Cells.

Targeting CD22 in Childhood B-Precursor Acute Lymphoblastic Leukemia (Pre-B ALL): Pre-Clinical Studies and Phase I Trial of the Anti-CD22 Immunotoxin CAT-3888 (BL22).

Contribution of STAT3 to Activation of Survivin by Granulocyte-Macrophage Colony-Stimulating Factor in CD34+ Cells.

Expression of Inhibitor-of-Apoptosis Protein (IAP) Livin in Pediatric Acute Lymphoblastic Leukemia (ALL) Cells.

Endogenous TNFα Mediates Cell Survival and Chemotherapy Resistance by Activating the PI3K/Akt Pathway in Childhood Acute Lymphoblastic Leukemia.

Vitamin K3 Selectively Induces Apoptosis in Acute Lymphoblastic Leukemia Cells with Constitutive Activation of IKKα/NF-kB Activation.

Loss of PTEN Expression Induces NF-kB Via PI3K/Akt Pathway Involving Resistance to Chemotherapy in Acute Lymphoblastic Leukemia Cell Lines.

An Alternatively Spliced Survivin Variant Is Positively Regulated by p53 and Sensitizes Leukemia Cells to Chemotherapy.

MDM2 induces NF-κB/p65 expression transcriptionally through Sp1-binding sites: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia

Expression and Regulation of Bcl-2, Bcl-xl, and Bax Correlate With p53 Status and Sensitivity to Apoptosis in Childhood Acute Lymphoblastic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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