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Lucas McDonald
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Journal Articles

Magnetic resonance imaging maps spatiotemporal changes in bone marrow composition of murine JAKV617F models of myelofibrosis during progression and therapy

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Brian Ross, Christopher Bonham, Youngsoon Jang, Kevin Heist, Lucas McDonald, Amanda Fair, Dariya Malyarenko, Thomas Chenevert
Journal: Blood
Blood (2025) 146 (Supplement 1): 2560.
https://doi.org/10.1182/blood-2025-2560
Published: 2025
Journal Articles

Momelotinib inhibition of JAK/STAT in a mouse JAKV617F myelofibrosis model showed concurrent activation of p-ERK and p-AKT which was reversed by combination therapy using LP-182, a novel MEK/PI3K/mTOR inhibitor

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Brian Ross, Youngsoon Jang, Kevin Heist, Lucas McDonald, Amanda Fair, Hasaruwani Kiridena, Thomas Chenevert
Journal: Blood
Blood (2025) 146 (Supplement 1): 4329.
https://doi.org/10.1182/blood-2025-4329
Published: 2025