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Lucas Wadley
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Journal Articles

Disruption of IL-10 receptor signaling promotes hematopoietic stem cell exhaustion and clonal expansion of JAK2V617F mutant cells during inflammatory stress

Free
Lucas Wadley, Xin (Helen) Huang, Jianhong Heidmann, Hew Yeng Lai, Eshika Arora, Eli Soyfer, Angela Fleischman
Journal: Blood
Blood (2025) 146 (Supplement 1): 855.
https://doi.org/10.1182/blood-2025-855
Published: 2025
Journal Articles

High-frequency monitoring of clonal dynamics in MPN using saliva and peripheral blood during interferon therapy

Free
Eli Soyfer, Jianhong Heidmann, Xin (Helen) Huang, Valeria Rangel, Krista Tsai, Lucas Wadley, Brian Sworder, Nicholas Pannunzio, Angela Fleischman
Journal: Blood
Blood (2025) 146 (Supplement 1): 7268.
https://doi.org/10.1182/blood-2025-7268
Published: 2025
Journal Articles

Uncovering Non-Canonical Signalling Mediated By JAK2V617F in Myeloproliferative Neoplasms

Free
Lucas Wadley, Hew Yeng Lai, Eshika Arora, Helen Huang, Jianhong C Heidmann, Dennis Jing, Lauren Chen, Angela G. Fleischman
Journal: Blood
Blood (2024) 144 (Supplement 1): 3134.
https://doi.org/10.1182/blood-2024-198767
Published: 2024
Journal Articles

Wild-Type Calreticulin Downmodulates MPL and Impacts HSC Self-Renewal

Free
Kiana K. Guillermo, Stefan Brooks, Lucas Wadley, Jianhong C Heidmann, Helen Huang, Jane Chen, Aanya Amin, Anaya Qamar, Brianna Hoover, Gajalakshmi Ramanathan, Angela G. Fleischman
Journal: Blood
Blood (2023) 142 (Supplement 1): 1782.
https://doi.org/10.1182/blood-2023-189705
Published: 2023
Journal Articles

JAK2V617F Activates IL-10R Signalling Potentially through Transactivation of JAK1

Free
Lucas Wadley, Hew Yeng Lai, Eshika Arora, Helen Huang, Dennis Jing, Angela G. Fleischman
Journal: Blood
Blood (2023) 142 (Supplement 1): 6333.
https://doi.org/10.1182/blood-2023-187871
Published: 2023