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Journal Articles

Arsenic Trioxide Synergizes with FLT3 Tyrosine Kinase Inhibitors to Kill FLT3-ITD + Leukemic Cells through Depressed Production and Degradation of FLT3 Protein

Kozo Nagai, MD PhD, Lihong Hou, MD PhD, Li Li, MD PhD, Bao Nguyen, M.S., Courtney M Shirley, PhD, Hayley S Ma, PhD, Mark J. Levis, MD PhD, Amy S. Duffield, MD PhD, Donald Small, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1568.
https://doi.org/10.1182/blood.V128.22.1568.1568
Published: 2016
Journal Articles

All- trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD + leukemia stem cells in vitro and in vivo

Hayley S. Ma, Sarah M. Greenblatt, Courtney M. Shirley, Amy S. Duffield, J. Kyle Bruner, Li Li, Bao Nguyen, Eric Jung, Peter D. Aplan, Gabriel Ghiaur, Richard J. Jones, Donald Small
Journal: Blood
Blood (2016) 127 (23): 2867–2878.
https://doi.org/10.1182/blood-2015-05-646786
Published: 2016
Includes: Supplemental data
Journal Articles

FLT3 Inhibition and Retinoid Signaling Overcome Stromal Protection to Target FLT3/ITD-Expressing Leukemia Stem Cells in the Bone Marrow Microenvironment

Hayley S Ma, PhD, Megan E McCray, BA, Courtney M Shirley, PhD, Amy S. Duffield, MD PhD, J Kyle Bruner, Li Li, PhD, Bao Nguyen, M.S., Sarah Greenblatt, PhD, Eric Jung, BS, Peter D. Aplan, MD, Richard J Jones, MD, Donald Small, MD PhD, Gabriel Ghiaur, MD PhD
Journal: Blood
Blood (2015) 126 (23): 790.
https://doi.org/10.1182/blood.V126.23.790.790
Published: 2015
Journal Articles

Genetic and Pharmacologic Notch4 Inhibition Synergizes with FLT3 Tyrosine Kinase Inhibition in Vitro to More Effectively Eliminate FLT3/ITD-Positive Leukemia Cells

Courtney M. Shirley, PhD, S. Haihua Chu, PhD, Yandan Yang, PhD, George W. Wright, PhD, Louis M. Staudt, MD PhD, Donald Small, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3583.
https://doi.org/10.1182/blood.V124.21.3583.3583
Published: 2014
Journal Articles

Bortezomib induction of C/EBPβ mediates Epstein-Barr virus lytic activation in Burkitt lymphoma

Courtney M. Shirley, Jianmeng Chen, Meir Shamay, Huili Li, Cynthia A. Zahnow, S. Diane Hayward, Richard F. Ambinder
Journal: Blood
Blood (2011) 117 (23): 6297–6303.
https://doi.org/10.1182/blood-2011-01-332379
Published: 2011
Journal Articles

When differentiation goes viral

Courtney M. Shirley, Richard F. Ambinder
Journal: Blood
Blood (2011) 117 (22): 5790–5791.
https://doi.org/10.1182/blood-2011-04-344135
Published: 2011
Journal Articles

9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia

WH Jr Miller, A Jakubowski, WP Tong, VA Miller, JR Rigas, F Benedetti, GM Gill, JA Truglia, E Ulm, M Shirley
Journal: Blood
Blood (1995) 85 (11): 3021–3027.
https://doi.org/10.1182/blood.V85.11.3021.bloodjournal85113021
Published: 1995