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Journal Articles

Final Analysis of the Daliah Trial: A Randomized Phase III Trial of Interferon-α Versus Hydroxyurea in Patients with MPN

Blood (2023) 142 (Supplement 1): 746.

https://doi.org/10.1182/blood-2023-173127

Published: 2023

Journal Articles

Quality of Life and Symptom Burden of Patients with MPN during Treatment with Hydroxyurea or Pegylated Interferon-alpha2: Results from a Randomized Controlled Trial

Blood (2022) 140 (Supplement 1): 1794–1796.

https://doi.org/10.1182/blood-2022-156445

Published: 2022

Journal Articles

Interferon-alpha2 Favorably Impacts Deregulated Atherosclerosis Genes in Polycythemia Vera and Related Neoplasms

Vibe Skov, Mads Thomassen, Lasse Kjær, Morten Kranker Larsen, Christina Ellervik, Trine Alma Knudsen, Torben A. Kruse, Hans Carl Hasselbalch

Blood (2022) 140 (Supplement 1): 9604–9605.

https://doi.org/10.1182/blood-2022-157906

Published: 2022

Journal Articles

The Impact of Somatic Mutations upon the Response to Combination Therapy with Ruxolitinib and Interferon in MPN Patients

Vibe Skov, Anders Lindholm Sørensen, Trine Alma Knudsen, Mads Emil Bjørn, Christina Ellervik, Morten Kranker Larsen, Christina Schjellerup Schjellerup Eickhardt-Dalbøge, Sarah Friis Christensen, Mads Thomassen, Torben A Kruse, Hans C. Hasselbalch

Blood (2021) 138 (Supplement 1): 3589.

https://doi.org/10.1182/blood-2021-152154

Published: 2021

Journal Articles

Significantly Upregulated Thrombo-Inflammatory Genes Are Normoregulated or Significantly Downregulated during Treatment with Interferon-Alpha2 in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Torben A Kruse, Hans Hasselbalch, MD

Blood (2019) 134 (Supplement_1): 2978.

https://doi.org/10.1182/blood-2019-131698

Published: 2019

Journal Articles

Highly Deregulated Fibulins in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Torben A Kruse, Hans Hasselbalch, MD

Blood (2019) 134 (Supplement_1): 5396.

https://doi.org/10.1182/blood-2019-130560

Published: 2019

Journal Articles

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Blood (2019) 134 (Supplement_1): 4202.

https://doi.org/10.1182/blood-2019-126164

Published: 2019

Journal Articles

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Impacts Deregulation of Oxidative Stress Genes and Antioxidative Defence Mechanisms. Potential Implications of IFN-Alfa Induced Changes in TP53, NRF2 and CXCR4 for Genomic Instability and CD34+ Mobilisation

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 4326.

https://doi.org/10.1182/blood-2018-99-112109

Published: 2018

Journal Articles

The Impact of the Mutational Landscape upon the Molecular Responses to Interferon-Alfa2 in Calr-Mutated MPN Patients

Vibe Skov, PhD, Lasse Kjær, PhD, Mads Thomassen, PhD, Steffen Koschmieder, MD, Julia Czech, Nicolas Chatain, PhD, Niels Pallisgaard, Sabrina Cordua, MD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 4327.

https://doi.org/10.1182/blood-2018-99-119158

Published: 2018

Journal Articles

The Impact of Interferon on Interferon-Related Genes in Polycythemia Vera and Allied Neoplasms

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 4328.

https://doi.org/10.1182/blood-2018-99-110602

Published: 2018

Journal Articles

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

Vibe Skov, PhD, Katrine LM Schmidt, Kasper Mønsted Pedersen, MD, Bettina Hansen, Tobias Wirenfeldt Klausen, M.S., Torben A Kruse, Mads Thomassen, PhD, Lasse Kjær, PhD, Christina Ellervik, Associate Professor, MD PhD, Morten Holmstrøm, MD, Bjørn Nexø, Hans Carl Hasselbalch, Professor, dr.MD, Magdalena J Laska

Blood (2018) 132 (Supplement 1): 5488.

https://doi.org/10.1182/blood-2018-99-118080

Published: 2018

Journal Articles

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Influences Deregulated Inflammation and Immune Genes in Polycythemia Vera and Allied Neoplasms

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 5490.

https://doi.org/10.1182/blood-2018-99-118690

Published: 2018

Journal Articles

Extracellular Matrix-Related Genes Are Deregulated in Peripheral Blood from Patients with Myelofibrosis and Related Neoplasms

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Caroline Riley, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 5491.

https://doi.org/10.1182/blood-2018-99-117122

Published: 2018

Journal Articles

Long-Term Efficacy and Safety of Recombinant Interferon Alpha-2 Vs. Hydroxyurea in Polycythemia Vera: Preliminary Results from the Three-Year Analysis of the Daliah Trial - a Randomized Controlled Phase III Clinical Trial

Blood (2018) 132 (Supplement 1): 580.

https://doi.org/10.1182/blood-2018-99-111255

Published: 2018

Journal Articles

Whole Blood Transcriptional Profiling Reveals Highly Deregulated Atherosclerosis Genes in Myeloproliferative Cancer

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Caroline Riley, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 3071.

https://doi.org/10.1182/blood-2018-99-117981

Published: 2018

Journal Articles

Safety and Efficacy of Combination Therapy of Interferon-Alpha2 + JAK1-2 Inhibitor in the Philadelphia-Negative Chronic Myeloproliferative Neoplasms. Preliminary Results from the Danish Combi-Trial - an Open Label, Single Arm, Non-Randomized Multicenter Phase II Study

Stine Ulrik Mikkelsen, MD, Lasse Kjær, MSc, PhD, Vibe Skov, MSc, PhD, Mads Emil Bjørn, MD PhDStudent, Christen Lykkegaard Andersen, MD PhD, Ole Weis Bjerrum, MD DMSc, Nana Brochmann, MD PhDStudent, Daniel El Fassi, MD PhD, Torben A Kruse, Professor, PhD, Thomas Stauffer Larsen, MD PhD, Torben Mourits-Andersen, MD, Claus Henrik Nielsen, MD Professor, DMSc, Niels Pallisgaard, MSc, Mads Thomassen, MSc, PhD, Hans Carl Hasselbalch, MD Professor, DMSc

Blood (2015) 126 (23): 824.

https://doi.org/10.1182/blood.V126.23.824.824

Published: 2015

Journal Articles

The Impact of Interferon-alpha2 on HLA-Genes in Patients with Polycythemia Vera and Related Neoplasms

Vibe Skov, MSc, PhD, Caroline H Riley, Mads Thomassen, MSc, PhD, Lasse Kjær, MSc, PhD, Thomas Stauffer Larsen, MD PhD, Morten K Jensen, Ole Weis Bjerrum, MD DMSc, Torben A Kruse, Professor, PhD, Hans Carl Hasselbalch, MD Professor, DMSc

Blood (2015) 126 (23): 4097.

https://doi.org/10.1182/blood.V126.23.4097.4097

Published: 2015

Journal Articles

DNA Methylation Profiling of Sorted Cells from Myelofibrosis Patients reveals Aberrant Epigenetic Regulation of Immune Pathways and identifies Early MPN Driver Genes

Hans Carl Hasselbalch, MD PhD, Helene Myrtue Nielsen, Cand.scient, Fazila Asmar, MD, Christen Lykkegaard Andersen, MD, Lasse Sommer Kristensen, PhD, Kruse A Torben, Mads Thomassen, PhD, Thomas Stauffer Larsen, Vibe Skov, PhD, Caroline Riley, MD, Lise Lotte Hansen, PhD, Morten K. Jensen, MD, Ole Weis Bjerrum, MD, Vasu Punj, Kirsten Grønbæk, MD DMSc

Blood (2014) 124 (21): 4576.

https://doi.org/10.1182/blood.V124.21.4576.4576

Published: 2014

Journal Articles

Gene Expression Profiling with Principal Component Analysis Depicts the Biological Continuum From Essential Thrombocythemia Over Polycythemia Vera to Myelofibrosis

Vibe Skov, PhD, Thomas Stauffer Larsen, MD, PhD, Mads Thomassen, PhD, Caroline Riley, MD, Morten Krogh Jensen, MD, DMSc, Ole Weis Bjerrum, MD, DMSc, Torben A Kruse, Hans Carl Hasselbalch, MD, DMSc

Blood (2010) 116 (21): 4115.

https://doi.org/10.1182/blood.V116.21.4115.4115

Published: 2010

Journal Articles

High Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule(CEACAM) 6 In Primary Myelofibrosis

Hans Carl Hasselbalch, MD, DMSc, Vibe Skov, PhD, Thomas Stauffer Larsen, MD, PhD, Mads Thomassen, PhD, Caroline Riley, MD, Morten Krogh Jensen, MD, DMSc, Ole Weis Bjerrum, MD, DMSc, Torben A Kruse

Blood (2010) 116 (21): 4116.

https://doi.org/10.1182/blood.V116.21.4116.4116

Published: 2010

NARROW

Final Analysis of the Daliah Trial: A Randomized Phase III Trial of Interferon-α Versus Hydroxyurea in Patients with MPN

Quality of Life and Symptom Burden of Patients with MPN during Treatment with Hydroxyurea or Pegylated Interferon-alpha2: Results from a Randomized Controlled Trial

Interferon-alpha2 Favorably Impacts Deregulated Atherosclerosis Genes in Polycythemia Vera and Related Neoplasms

The Impact of Somatic Mutations upon the Response to Combination Therapy with Ruxolitinib and Interferon in MPN Patients

Significantly Upregulated Thrombo-Inflammatory Genes Are Normoregulated or Significantly Downregulated during Treatment with Interferon-Alpha2 in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Highly Deregulated Fibulins in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Impacts Deregulation of Oxidative Stress Genes and Antioxidative Defence Mechanisms. Potential Implications of IFN-Alfa Induced Changes in TP53, NRF2 and CXCR4 for Genomic Instability and CD34+ Mobilisation

The Impact of the Mutational Landscape upon the Molecular Responses to Interferon-Alfa2 in Calr-Mutated MPN Patients

The Impact of Interferon on Interferon-Related Genes in Polycythemia Vera and Allied Neoplasms

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Influences Deregulated Inflammation and Immune Genes in Polycythemia Vera and Allied Neoplasms

Extracellular Matrix-Related Genes Are Deregulated in Peripheral Blood from Patients with Myelofibrosis and Related Neoplasms

Long-Term Efficacy and Safety of Recombinant Interferon Alpha-2 Vs. Hydroxyurea in Polycythemia Vera: Preliminary Results from the Three-Year Analysis of the Daliah Trial - a Randomized Controlled Phase III Clinical Trial

Whole Blood Transcriptional Profiling Reveals Highly Deregulated Atherosclerosis Genes in Myeloproliferative Cancer

Safety and Efficacy of Combination Therapy of Interferon-Alpha2 + JAK1-2 Inhibitor in the Philadelphia-Negative Chronic Myeloproliferative Neoplasms. Preliminary Results from the Danish Combi-Trial - an Open Label, Single Arm, Non-Randomized Multicenter Phase II Study

The Impact of Interferon-alpha2 on HLA-Genes in Patients with Polycythemia Vera and Related Neoplasms

DNA Methylation Profiling of Sorted Cells from Myelofibrosis Patients reveals Aberrant Epigenetic Regulation of Immune Pathways and identifies Early MPN Driver Genes

Gene Expression Profiling with Principal Component Analysis Depicts the Biological Continuum From Essential Thrombocythemia Over Polycythemia Vera to Myelofibrosis

High Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule(CEACAM) 6 In Primary Myelofibrosis

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American Society of Hematology

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