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Journal Articles

Preliminary Results of the Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Two Phase IIa Dose Expansion Cohorts in Relapsed/Refractory TP53 Wild-Type Peripheral T-Cell Lymphoma

Andrei R. Shustov, MD, Steven M. Horwitz, MD, Jasmine Zain, MD, Manish R Patel, MD, Sanjay Goel, MD, Lubomir Sokol, MD PhD, Funda Meric-Bernstam, MD, Geoffrey Shapiro, MD PhD, Sunita Dwivedy Nasta, MD, Murali Janakiram, MD MS, David M Weinstock, MD, Ronald Korn, MD PhD, Marie Payton, MBA, D. Allen Annis, PhD, Dawn Pinchasik, MD, Manuel Aivado, MD PhD, Amitkumar Mehta, MD

Blood (2018) 132 (Supplement 1): 1623.

https://doi.org/10.1182/blood-2018-99-116780

Published: 2018

Journal Articles

Phase 1/1b Study of the Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2, As Monotherapy or in Combination with Cytarabine for the Treatment of Relapsed/Refractory AML and Advanced MDS with TP53 Wild-Type

David A Sallman, MD, Uma Borate, MD, Elizabeth H. Cull, MD, William B. Donnellan, MD, Rami S. Komrokji, MD, Ulrich G. Steidl, MD PhD, Maria M Corvez, Marie Payton, MBA, D. Allen Annis, PhD, Dawn Pinchasik, MD, Manuel Aivado, MD PhD, Amit Verma, MD

Blood (2018) 132 (Supplement 1): 4066.

https://doi.org/10.1182/blood-2018-99-118780

Published: 2018

Journal Articles

Pseudoprogression (PsP) in Patients with Peripheral T-Cell Lymphoma (PTCL) Treated with the Novel Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2

Andrei R. Shustov, MD, Amitkumar Mehta, MD, Lubomir Sokol, MD PhD, Luis A. Carvajal, PhD, Vincent Guerlavais, PhD, Manoj Samant, PhD, Narayana Narasimhan, PhD, David Sutton, BSc, D. Allen Annis, PhD, Dawn Pinchasik, MD, Manuel Aivado, MD PhD, Ronald Korn, MD PhD

Blood (2018) 132 (Supplement 1): 5348.

https://doi.org/10.1182/blood-2018-99-119489

Published: 2018

Journal Articles

Long-Term Safety and Efficacy of Oral Eltrombopag for the Treatment of Subjects with Idiopathic Thrombocytopenic Purpura (ITP): Preliminary Data from the EXTEND Study.

James B. Bussel, MD, Gregory Cheng, MD, Lidia Kovaleva, MD, Mansoor N. Saleh, MD, Balkis Meddeb, MD, Bhabita Mayer, PhD, J. Lee Fraser, PhD, Manuel Aivado, MD

Blood (2007) 110 (11): 566.

https://doi.org/10.1182/blood.V110.11.566.566

Published: 2007

Journal Articles

A Transcriptional Signature Distinguishing Short and Long-Term Surviving Patients with MDS.

Akos Czibere, MD, Christian Prall, MD, Ulrich Steidl, MD, PhD, Ingmar Bruns, MD, Andrea Kuendgen, MD, Aristoteles Giagounidis, MD, Rainer Haas, MD, Guido Kobbe, MD, Ulrich Germing, MD, Manuel Aivado, MD

Blood (2006) 108 (11): 4866.

https://doi.org/10.1182/blood.V108.11.4866.4866

Published: 2006

Journal Articles

Essential Role of Jun Family Transcription Factors in PU.1-Induced Leukemic Stem Cell Transformation.

Ulrich Steidl, MD, PhD, Frank Rosenbauer, PhD, Roel G.W Verhaak, Xuesong Gu, PhD, Hasan H. Otu, PhD, Shakir Kolia, PhD, Bronwyn M. Owens, PhD, Steffen Klippel, PhD, Katharina Wagner, MD, Manuel Aivado, MD, Emmanuelle Passegue, PhD, Towia A. Libermann, PhD, Ruud Delwel, PhD, Daniel G. Tenen, MD

Blood (2005) 106 (11): 463.

https://doi.org/10.1182/blood.V106.11.463.463

Published: 2005

Journal Articles

Age-Related Transcription Levels of KU70 and BIK in CD34+ Hematopoietic Stem and Progenitor Cells.

Wolf C. Prall, MD, Akos Czibere, MD, Franck Grall, PhD, Luiz F. Zerbini, PhD, Markus Jaeger, MD, Dimitrios Spentzos, MD, Towia A. Libermann, PhD, Norbert Gattermann, MD, Manuel Aivado, MD, Rainer Haas, MD

Blood (2005) 106 (11): 4205.

https://doi.org/10.1182/blood.V106.11.4205.4205

Published: 2005

Journal Articles

Exisulind Selectively Induces Apoptosis Via C-Jun Kinase Activation in MDS and sAML/MDS.

Akos Czibere, MD, Wolf C. Prall, MD, Sabine Knipp, MD, Andrea Kuendgen, MD, Luiz F. Zerbini, PhD, Ulrich Germing, MD, Rainer Haas, MD, Towia A. Libermann, PhD, Norbert Gattermann, MD, Manuel Aivado, MD

Blood (2005) 106 (11): 4902.

https://doi.org/10.1182/blood.V106.11.4902.4902

Published: 2005

Journal Articles

Treatment of Del(5q) Myelodysplastic Syndrome with All-Trans-Retinoic Acid and Tocopherol-α.

Aristoteles A.N. Giagounidis, MD, Sabine Haase, Ulrich Germing, MD, PhD, Claudia Schoch, MD, PhD, Brigitte Schlegelberger, PhD, Ludwig Wilkens, PhD, Guntram Büsche, MD, Hans H. Kreipe, MD, PhD, Manuel Aivado, MD, Michael Lübbert, MD, PhD, Arnold Ganser, MD, PhD, Carlo Aul, MD, PhD

Blood (2004) 104 (11): 4729.

https://doi.org/10.1182/blood.V104.11.4729.4729

Published: 2004

Journal Articles

Serum Protein Profiling with Mass Spectrometry for the Diagnosis of Myelodysplastic Syndromes.

Blood (2004) 104 (11): 2362.

https://doi.org/10.1182/blood.V104.11.2362.2362

Published: 2004

Journal Articles

Knockdown of the Transcription Factor PU.1 Causes Characteristic Transcriptional Changes in Hematopoietic Stem Cells Prior to Leukemic Transformation.

Ulrich Steidl, MD PhD, Frank Rosenbauer, PhD, Xuesong Gu, PhD, Bronwyn Owens, PhD, Steffen Klippel, PhD, Katharina Wagner, MD, Manuel Aivado, MD, Towia A. Libermann, PhD, Daniel G. Tenen, MD

Blood (2004) 104 (11): 1112.

https://doi.org/10.1182/blood.V104.11.1112.1112

Published: 2004

Journal Articles

The Influence of Age and Gender on the Prognostic Impact of Karytoypic Subgroups in Myelodysplastic Syndromes - a Multicenter Analysis.

Thomas Noesslinger, MD, Ulrich Germing, MD, PD, Barbara Hildebrandt, MD, Claudia Strupp, MD, Manuel Aivado, MD, Detlef Haase, MD, Julie Schanz, MD, Friedrich Wimazal, MD, Wolfgang Sperr, MD, Valent Peter, MD, Lubbert Michael, MD, PD, Otto Krieger, MD, Norbert Gattermann, MD, Aristoteles Giagounidis, MD, Heinz Tuchler, Rainer Haas, MD, Carlo Aul, MD, Michael Pfeilstocker, MD, PD

Blood (2004) 104 (11): 1448.

https://doi.org/10.1182/blood.V104.11.1448.1448

Published: 2004

NARROW

Preliminary Results of the Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Two Phase IIa Dose Expansion Cohorts in Relapsed/Refractory TP53 Wild-Type Peripheral T-Cell Lymphoma

Phase 1/1b Study of the Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2, As Monotherapy or in Combination with Cytarabine for the Treatment of Relapsed/Refractory AML and Advanced MDS with TP53 Wild-Type

Pseudoprogression (PsP) in Patients with Peripheral T-Cell Lymphoma (PTCL) Treated with the Novel Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2

Long-Term Safety and Efficacy of Oral Eltrombopag for the Treatment of Subjects with Idiopathic Thrombocytopenic Purpura (ITP): Preliminary Data from the EXTEND Study.

A Transcriptional Signature Distinguishing Short and Long-Term Surviving Patients with MDS.

Essential Role of Jun Family Transcription Factors in PU.1-Induced Leukemic Stem Cell Transformation.

Age-Related Transcription Levels of KU70 and BIK in CD34+ Hematopoietic Stem and Progenitor Cells.

Exisulind Selectively Induces Apoptosis Via C-Jun Kinase Activation in MDS and sAML/MDS.

Treatment of Del(5q) Myelodysplastic Syndrome with All-Trans-Retinoic Acid and Tocopherol-α.

Serum Protein Profiling with Mass Spectrometry for the Diagnosis of Myelodysplastic Syndromes.

Knockdown of the Transcription Factor PU.1 Causes Characteristic Transcriptional Changes in Hematopoietic Stem Cells Prior to Leukemic Transformation.

The Influence of Age and Gender on the Prognostic Impact of Karytoypic Subgroups in Myelodysplastic Syndromes - a Multicenter Analysis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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