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Journal Articles

Potential Therapeutic Applications of Jak2 Inhibitors in Beta-Thalassemia and Sickle Cell Disease,

Carla Casu, PhD, Pedro Ramos, PhD, Luca Melchiori, PhD, Ella Guy, Eliezer A. Rachmilewitz, Patricia Giardina, MD, Robert W Grady, PhD, Maria de Sousa, MD, PhD, Stefano Rivella, PhD

Blood (2011) 118 (21): 3187.

https://doi.org/10.1182/blood.V118.21.3187.3187

Published: 2011

Journal Articles

Hfe Modulates the Response to Erythopoietic Stress In Wt Mice by Two Distinct Mechanisms

Pedro Ramos, PhD, Ella Guy, Robert W Grady, PhD, Maria de Sousa, MD, PhD, Stefano Rivella, PhD

Blood (2010) 116 (21): 4251.

https://doi.org/10.1182/blood.V116.21.4251.4251

Published: 2010

Journal Articles

ß-Thalassemic Mice Require Functional Hfe to Modulate Hepcidin Expression In Response to Iron Overload

Pedro Ramos, Sara Gardenghi, PhD, Robert W Grady, PhD, Maria de Sousa, MD, PhD, Stefano Rivella, PhD

Blood (2010) 116 (21): 2063.

https://doi.org/10.1182/blood.V116.21.2063.2063

Published: 2010

Journal Articles

Absence of the Hemochromatosis Gene Hfe Confers Protection Under Conditions of Stress Erythropoiesis.

Pedro Ramos, Ella Guy, Nan Chen, Sara Gardenghi, Robert W. Grady, PhD, Maria De Sousa, MD, Stefano Rivella, PhD

Blood (2009) 114 (22): 4044.

https://doi.org/10.1182/blood.V114.22.4044.4044

Published: 2009

Journal Articles

Macrophage Depletion Leads to Modification of Thalassemic Phenotype.

Pedro Ramos, Ella Guy, Nan Chen, Robert W. Grady, PhD, Barry S. Coller, MD, Maria De Sousa, MD, Stefano Rivella, PhD

Blood (2009) 114 (22): 2023.

https://doi.org/10.1182/blood.V114.22.2023.2023

Published: 2009

Journal Articles

Hepcidin: A Clue for a New Role for Lymphocytes.

Jorge P Pinto, PhD, Vera Dias, Heinz Zoller, MD, Pedro N Rodrigues, PhD, Helena Carmo, Pedro Ramos, Félix Carvalho, PhD, Graça Porto, MD, PhD, Maria de Sousa, MD, PhD

Blood (2009) 114 (22): 1999.

https://doi.org/10.1182/blood.V114.22.1999.1999

Published: 2009

Journal Articles

Potential Use of Jak2 Inhibitors to Limit Ineffective Erythropoiesis and Reverse Splenomegaly in β-Thalassemia.

Luca Melchiori, Ella Guy, Ilaria Libani, Ph.D, Raffaella Schirò, MD, Ph.D, Pedro Ramos, Laura Breda, Ph.D, Amy Chadburn, MD, Yi-Fang Liu, Maria De Sousa, MD, Eliezer Rachmilewitz, M.D, Patricia J Giardina, MD, Robert W Grady, Ph.D, Stefano Rivella, Ph.D

Blood (2008) 112 (11): 1877.

https://doi.org/10.1182/blood.V112.11.1877.1877

Published: 2008

Journal Articles

Absence of the Hemochromatosis Gene HFE Confers Protection Under Conditions of Stress Erythropoiesis.

Pedro Ramos, Ella Guy, Laura Breda, PhD, Sara Gardenghi, PhD, Robert W Grady, Ph.D, Maria De Sousa, MD, Stefano Rivella, PhD

Blood (2008) 112 (11): 3848.

https://doi.org/10.1182/blood.V112.11.3848.3848

Published: 2008

Journal Articles

Accelerated Proliferation and Limited Differentiation, Mediated through Jak2, Exacerbate Ineffective Erythropoiesis in β-Thalassemia.

Ella Guy, Ilaria Libani, PhD, Luca Melchiori, Thomas Scholzen, PhD, Raffaella Schiro, MD, Pedro Ramos, Margrit Kernbach, Bettina Baron-Luehr, Laura Breda, PhD, Matteo Porotto, PhD, Maria de Sousa, MD, Maria Domenica Cappellini, MD, Patricia J. Giardina, MD, Robert W. Grady, PhD, Johannes Gerdes, PhD, Stefano Rivella, PhD

Blood (2007) 110 (11): 275.

https://doi.org/10.1182/blood.V110.11.275.275

Published: 2007

Journal Articles

Ineffective Erythropoiesis in β-Thalassemia Is Characterized by Increased Iron Absorption Mediated by down Regulation of Hepcidin and up Regulation of Ferroportin.

Sara Gardenghi, PhD, Maria Marongiu, Pedro Ramos, Ella Guy, Laura Breda, PhD, Amy Chadburn, MD, Yifang Liu, Gideon Rechavi, MD, Ninette Amariglio, PhD, E.A. Rachmilewitz, MD, Diedra Wrighting, PhD, Nancy C. Andrews, MD, Maria de Sousa, MD, Patricia Giardina, MD, Robert W. Grady, PhD, Stefano Rivella, PhD

Blood (2006) 108 (11): 1543.

https://doi.org/10.1182/blood.V108.11.1543.1543

Published: 2006

Journal Articles

Role of HFE in Hepatic Iron Overload: Novel Findings Demonstrate Direct Effects of Mutant C282Y on Hepcidin and Calreticulin mRNA Expression.

Jorge P. Pinto, PhD, Pedro Ramos, Sergio de Almeida, Susana Oliveira, Laura Breda, PhD, Marek Michalak, PhD, Stefano Rivella, PhD, Maria de Sousa, MD, PhD

Blood (2006) 108 (11): 1549.

https://doi.org/10.1182/blood.V108.11.1549.1549

Published: 2006

NARROW

Potential Therapeutic Applications of Jak2 Inhibitors in Beta-Thalassemia and Sickle Cell Disease,

Hfe Modulates the Response to Erythopoietic Stress In Wt Mice by Two Distinct Mechanisms

ß-Thalassemic Mice Require Functional Hfe to Modulate Hepcidin Expression In Response to Iron Overload

Absence of the Hemochromatosis Gene Hfe Confers Protection Under Conditions of Stress Erythropoiesis.

Macrophage Depletion Leads to Modification of Thalassemic Phenotype.

Hepcidin: A Clue for a New Role for Lymphocytes.

Potential Use of Jak2 Inhibitors to Limit Ineffective Erythropoiesis and Reverse Splenomegaly in β-Thalassemia.

Absence of the Hemochromatosis Gene HFE Confers Protection Under Conditions of Stress Erythropoiesis.

Accelerated Proliferation and Limited Differentiation, Mediated through Jak2, Exacerbate Ineffective Erythropoiesis in β-Thalassemia.

Ineffective Erythropoiesis in β-Thalassemia Is Characterized by Increased Iron Absorption Mediated by down Regulation of Hepcidin and up Regulation of Ferroportin.

Role of HFE in Hepatic Iron Overload: Novel Findings Demonstrate Direct Effects of Mutant C282Y on Hepcidin and Calreticulin mRNA Expression.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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