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Journal Articles

Lack of IL6 Improves Recovery from Anemia of Inflammation Which Gets Hampered in Presence of Excess Iron

Sayantani Sinha, Ritama Gupta, Amaliris Guerra, Paige Mc Veigh, Sara Gardenghi, Carla Casu, Francesca Vinchi, Stefano Rivella

Blood (2021) 138 (Supplement 1): 3072.

https://doi.org/10.1182/blood-2021-153126

Published: 2021

Journal Articles

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Sayantani Sinha, PhD, Ritama Gupta, PhD, Jianbing Zhang, PhD, Amaliris Guerra, PhD, Ping La, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2019) 134 (Supplement_1): 940.

https://doi.org/10.1182/blood-2019-128826

Published: 2019

Journal Articles

Absence of Interleukin-6 Protects Murine Bone Marrow Erythropoiesis Under Inflammation, in a Process Reversible By Iron Mediated Reactive Oxygen Species Upregulation

Ritama Gupta, PhD, Roberta Chessa, PhD, La Ping, PhD, Vania Lo Presti, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2017) 130 (Supplement 1): 2195.

https://doi.org/10.1182/blood.V130.Suppl_1.2195.2195

Published: 2017

Journal Articles

Targeting TMPRSS6 Using Antisense Technology for the Treatment of Beta-Thalassemia

Shuling Guo, PhD, Mariam Aghajan, PhD, Carla Casu, PhD, Sara Gardenghi, PhD, Sheri Booten, Stefano Rivella, PhD, Brett P. Monia, PhD

Blood (2015) 126 (23): 753.

https://doi.org/10.1182/blood.V126.23.753.753

Published: 2015

Journal Articles

A Double Knock out of Hepcidin and IL6 Demonstrates Independent Roles of the Two Genes in Anemia of Inflammation

Ritama Gupta, MSc, Sara Gardenghi, PhD, Lori Bystrom, PhD, Roberta Chessa, PhD, Stefano Rivella, PhD

Blood (2015) 126 (23): 2221.

https://doi.org/10.1182/blood.V126.23.2221.2221

Published: 2015

Journal Articles

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia

Rajasekhar N. V. S. Suragani, Sharon M. Cawley, Robert Li, Samantha Wallner, Mark J. Alexander, Aaron W. Mulivor, Sara Gardenghi, Stefano Rivella, Asya V. Grinberg, R. Scott Pearsall, Ravindra Kumar

Blood (2014) 123 (25): 3864–3872.

https://doi.org/10.1182/blood-2013-06-511238

Published: 2014

Includes: Supplemental data

Journal Articles

Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus

Sara Gardenghi, Tom M. Renaud, Alessandra Meloni, Carla Casu, Bart J. Crielaard, Laura M. Bystrom, Noa Greenberg-Kushnir, Barbra J. Sasu, Keegan S. Cooke, Stefano Rivella

Blood (2014) 123 (8): 1137–1145.

https://doi.org/10.1182/blood-2013-08-521625

Published: 2014

Includes: Supplemental data

Journal Articles

Macrophages Regulate Stress Erythropoiesis Through Direct Cellular Interactions Associated With Integrin β1-Focal Adhesion Kinase Signaling

Bart J Crielaard, MD, PhD, Carla Casu, PhD, Pedro Ramos, PhD, Sara Gardenghi, PhD, Laura Breda, PhD, Ritama Gupta, Stefano Rivella, PhD

Blood (2013) 122 (21): 307.

https://doi.org/10.1182/blood.V122.21.307.307

Published: 2013

Journal Articles

Distinct Roles For Hepcidin and Interleukin 6 In The Recovery From Anemia Following Administration Of Heat-Killed Brucella Abortus

Sara Gardenghi, PhD, Thomas M. Renaud, MD, Alessandra Meloni, PhD, Carla Casu, PhD, Bart J. Crielaard, PhD, Laura M. Bystrom, PhD, Noa Greenberg, MD, Barbra J. Sasu, PhD, Keegan S. Cooke, Stefano Rivella, PhD

Blood (2013) 122 (21): 430.

https://doi.org/10.1182/blood.V122.21.430.430

Published: 2013

Journal Articles

Treatment With Minihepcidin Peptide Improves Anemia and Iron Overload In a Mouse Model Of Thalassemia Intermedia

Carla Casu, PHD, Adam Goldberg, Elizabeta Nemeth, PhD, Tomas Ganz, MD, PhD, Sara Gardenghi, PhD, Brian MacDonald, Stefano Rivella, PhD

Blood (2013) 122 (21): 431.

https://doi.org/10.1182/blood.V122.21.431.431

Published: 2013

Journal Articles

Target TMPRSS6 Using Antisense Technology for the Treatment of Hereditary Hemochromatosis and β-Thalassemia

Shuling Guo, PhD, Carla Casu, Sara Gardenghi, PhD, Sheri Booten, Andy Watt, Susan Freier, Ph.D, Stefano Rivella, PhD, Brett P. Monia, PhD

Blood (2012) 120 (21): 481.

https://doi.org/10.1182/blood.V120.21.481.481

Published: 2012

Journal Articles

Genetic Loss of Tmprss6 Increases Effective Erythropoiesis in a Mouse Model of β-Thalassemia

David B. Stagg, BS, Sara Gardenghi, PhD, Stefano Rivella, PhD, Nancy C. Andrews, MD, PhD, Karin E. Finberg, MD, PhD

Blood (2012) 120 (21): 482.

https://doi.org/10.1182/blood.V120.21.482.482

Published: 2012

Journal Articles

Removal of Macrophages From the Erythroid Niche Impairs Stress Erythropoiesis but Improves Pathophysiology of Polycythemia Vera and Beta-Thalassemia

Pedro Ramos, PhD, Carla Casu, PhD, Sara Gardenghi, PhD, Laura Breda, Ph.D, Bart J Crielaard, PhD, Ritama Gupta, Undergraduate student, Ella Guy, Maria F Mariongiu, PhD, Ross L. Levine, Omar Abdel-Wahab, PhD, Benjamin L. Ebert, Nico van Rooijen, PhD, Saghi Ghaffari, MD, PhD, Robert W Grady, PhD, Patricia Giardina, MD, Stefano Rivella, PhD

Blood (2012) 120 (21): 81.

https://doi.org/10.1182/blood.V120.21.81.81

Published: 2012

Journal Articles

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling

Nermi L. Parrow, Sara Gardenghi, Pedro Ramos, Carla Casu, Robert W. Grady, Erik R. Anderson, Yatrik M. Shah, Huihui Li, Yelena Z. Ginzburg, Robert E. Fleming, Stefano Rivella

Blood (2012) 119 (13): 3187–3189.

https://doi.org/10.1182/blood-2012-01-405563

Published: 2012

Journal Articles

The Regulation of Hepcidin in β-Thalassemia

Nermi Parrow, PhD, Sara Gardenghi, PhD, Pedro Ramos, PhD, Yatrik Shah, PhD, Robert Fleming, MD, Carla Casu, PhD, Robert W Grady, PhD, Stefano Rivella, PhD

Blood (2011) 118 (21): 901.

https://doi.org/10.1182/blood.V118.21.901.901

Published: 2011

Journal Articles

Exogenous Apo-Transferrin Reduces Extramedullary and Increases Effectiveness of Erythropoiesis in a Mouse Model of Beta-Thalassemia Major

Huihui Li, MS, Sara Gardenghi, PhD, Leni vonBonsdorff, PhD, Stefano Rivella, PhD, Yelena Ginzburg, MD

Blood (2011) 118 (21): 1095.

https://doi.org/10.1182/blood.V118.21.1095.1095

Published: 2011

Journal Articles

Investigating the Role of Cytokines and Hepcidin in Anemia of Inflammation

Sara Gardenghi, PhD, Thomas M. Renaud, MD, Alessandra Meloni, PhD, Pedro Ramos, PhD, Carla Casu, PhD, Keegan S Cooke, Barbra J Sasu, PhD, Patricia Giardina, MD, Robert W Grady, PhD, Stefano Rivella, PhD

Blood (2011) 118 (21): 1046.

https://doi.org/10.1182/blood.V118.21.1046.1046

Published: 2011

Journal Articles

Enhanced erythropoiesis in Hfe -KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis

Pedro Ramos, Ella Guy, Nan Chen, Catia C. Proenca, Sara Gardenghi, Carla Casu, Antonia Follenzi, Nico Van Rooijen, Robert W. Grady, Maria de Sousa, Stefano Rivella

Blood (2011) 117 (4): 1379–1389.

https://doi.org/10.1182/blood-2010-09-307462

Published: 2011

Includes: Supplemental data

Journal Articles

Hepcidin as a Therapeutic Tool to Limit Iron Overload and Improve Anemia In β-Thalassemia

Sara Gardenghi, PhD, Pedro Ramos, Cindy N. Roy, PhD, Nancy C. Andrews, MD, PhD, Elizabeta Nemeth, PhD, Xiuli An, MD, PhD, Mohandas Narla, DSc, Yelena Ginzburg, MD, Eliezer A. Rachmilewitz, MD, Patricia Giardina, MD, Robert W Grady, Stefano Rivella, PhD

Blood (2010) 116 (21): 1009.

https://doi.org/10.1182/blood.V116.21.1009.1009

Published: 2010

Journal Articles

ß-Thalassemic Mice Require Functional Hfe to Modulate Hepcidin Expression In Response to Iron Overload

Pedro Ramos, Sara Gardenghi, PhD, Robert W Grady, PhD, Maria de Sousa, MD, PhD, Stefano Rivella, PhD

Blood (2010) 116 (21): 2063.

https://doi.org/10.1182/blood.V116.21.2063.2063

Published: 2010

NARROW

Lack of IL6 Improves Recovery from Anemia of Inflammation Which Gets Hampered in Presence of Excess Iron

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Absence of Interleukin-6 Protects Murine Bone Marrow Erythropoiesis Under Inflammation, in a Process Reversible By Iron Mediated Reactive Oxygen Species Upregulation

Targeting TMPRSS6 Using Antisense Technology for the Treatment of Beta-Thalassemia

A Double Knock out of Hepcidin and IL6 Demonstrates Independent Roles of the Two Genes in Anemia of Inflammation

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia

Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus

Macrophages Regulate Stress Erythropoiesis Through Direct Cellular Interactions Associated With Integrin β1-Focal Adhesion Kinase Signaling

Distinct Roles For Hepcidin and Interleukin 6 In The Recovery From Anemia Following Administration Of Heat-Killed Brucella Abortus

Treatment With Minihepcidin Peptide Improves Anemia and Iron Overload In a Mouse Model Of Thalassemia Intermedia

Target TMPRSS6 Using Antisense Technology for the Treatment of Hereditary Hemochromatosis and β-Thalassemia

Genetic Loss of Tmprss6 Increases Effective Erythropoiesis in a Mouse Model of β-Thalassemia

Removal of Macrophages From the Erythroid Niche Impairs Stress Erythropoiesis but Improves Pathophysiology of Polycythemia Vera and Beta-Thalassemia

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling

The Regulation of Hepcidin in β-Thalassemia

Exogenous Apo-Transferrin Reduces Extramedullary and Increases Effectiveness of Erythropoiesis in a Mouse Model of Beta-Thalassemia Major

Investigating the Role of Cytokines and Hepcidin in Anemia of Inflammation

Enhanced erythropoiesis in Hfe -KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis

Hepcidin as a Therapeutic Tool to Limit Iron Overload and Improve Anemia In β-Thalassemia

ß-Thalassemic Mice Require Functional Hfe to Modulate Hepcidin Expression In Response to Iron Overload

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American Society of Hematology

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American Society of Hematology

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