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Journal Articles

Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens

Kyra J. Fuchs, Marian van de Meent, M. Willy Honders, Indu Khatri, Michel G. D. Kester, Eva A. S. Koster, Georgia Koutsoumpli, Arnoud H. de Ru, Cornelis A. M. van Bergen, Peter A. van Veelen, Peter A. C. ’t Hoen, Peter van Balen, Erik B. van den Akker, J. Hendrik Veelken, Constantijn J. M. Halkes, J. H. Frederik Falkenburg, Marieke Griffioen

Blood (2024) 143 (18): 1856–1872.

https://doi.org/10.1182/blood.2023022343

Published: 2024

Includes: Supplemental data

Journal Articles

Immunotherapy Targeting Mutant Nucleophosmin-1 on Acute Myeloid Leukemia

Georgia Koutsoumpli, Dyantha I. van der Lee, Nina C. Groenland, M. Willy Honders, Rob C.M. de Jong, Renate S. Hagedoorn, Hendrik Veelken, Peter A. van Veelen, Dominik Lock, Mirjam H.M. Heemskerk, J.H.Frederik Falkenburg, Ian Johnston, Marieke Griffioen

Blood (2022) 140 (Supplement 1): 10243–10244.

https://doi.org/10.1182/blood-2022-158195

Published: 2022

Journal Articles

Large Scale Identification and Validation of 85 New HLA Class I-Restricted Minor Histocompatibility Antigens for Immune Monitoring and Modulation after Allogeneic Stem Cell Transplantation

Kyra J. Fuchs, M. Willy Honders, Marian van de Meent, Indu Khatri, Eva A.S. Koster, Cornelis A.M. van Bergen, Erik B. van den Akker, Constantijn J.M. Halkes, J.H. Frederik Falkenburg, Marieke Griffioen

Blood (2022) 140 (Supplement 1): 10196–10197.

https://doi.org/10.1182/blood-2022-157938

Published: 2022

Journal Articles

Broadly Applicable TCR Based Therapy for Multiple Myeloma Targeting the Jchain

Miranda H. Meeuwsen, Anne K. Wouters, Tassilo L.A. Wachsmann, Renate S. Hagedoorn, Michel G.D. Kester, Dennis F.G. Remst, Dirk M. van der Steen, Arnoud H. de Ru, Els P. van Hees, Marieke Griffioen, Peter A. van Veelen, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk

Blood (2022) 140 (Supplement 1): 4498–4499.

https://doi.org/10.1182/blood-2022-156923

Published: 2022

Journal Articles

Immunotherapy By Targeting CD45 in Mismatched HLA-DP to Treat Patients after Allogeneic Stem Cell Transplantation

Nadine E. Struckman, Sebastian Klobuch, Michel G.D. Kester, Wendy de Klerk, Arnoud H. de Ru, Mirjam H.M. Heemskerk, Peter A. van Veelen, Peter van Balen, J.H.Frederik Falkenburg, Marieke Griffioen

Blood (2022) 140 (Supplement 1): 4545–4546.

https://doi.org/10.1182/blood-2022-166282

Published: 2022

Journal Articles

Special Anatomical Subtypes of Diffuse Large B-Cell Lymphoma Have Distinct Tumor Microenvironments

Blood (2022) 140 (Supplement 1): 164–165.

https://doi.org/10.1182/blood-2022-156103

Published: 2022

Journal Articles

Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DM

Thuja Meurer, Pietro Crivello, Maximilian Metzing, Michel Kester, Dominik A. Megger, Weiqiang Chen, Peter A. van Veelen, Peter van Balen, Astrid M. Westendorf, Georg Homa, Sophia E. Layer, Amin T. Turki, Marieke Griffioen, Peter A. Horn, Barbara Sitek, Dietrich W. Beelen, J. H. Frederik Falkenburg, Esteban Arrieta-Bolaños, Katharina Fleischhauer

Blood (2021) 137 (7): 923–928.

https://doi.org/10.1182/blood.2020008464

Published: 2021

Includes: Supplemental data

Journal Articles

HLA-DM Mediates Permissiveness of HLA-DPB1 T Cell Epitope Mismatches in Unrelated HCT

Maximilian Metzing, Pietro Crivello, Thuja Meurer, Michel G.D. Kester, ing., Dominik Megger, Weiqiang Chen, Peter Van Balen, MD, Marieke Griffioen, PhD, Peter A. Horn, Barbara Sitek, J.H.Frederik Falkenburg, MD PhD, Esteban Arrieta-Bolaños, Katharina Fleischhauer, MD

Blood (2019) 134 (Supplement_1): 3211.

https://doi.org/10.1182/blood-2019-129921

Published: 2019

Journal Articles

Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 2762.

https://doi.org/10.1182/blood-2018-99-111115

Published: 2018

Journal Articles

Fusion Transcripts without Corresponding Cytogenetic Abnormalities in Acute Myeloid Leukemia: Implications for AML Pathogenesis

Irene J. Locher, Wibowo Arindrarto, M.Sc., Daniel M. Borràs, M.Sc., M. Willy Honders, ing., Rick H. de Leeuw, ing., Wilma G.M. Kroes, PhD, Peter de Knijff, PhD, Cornelis A.M. van Bergen, PhD, Peter A.C. 't Hoen, PhD, Szymon M. Kielbasa, PhD, Jeroen F.J. Laros, PhD, Marieke Griffioen, PhD, Hendrik Veelken, MD PhD

Blood (2017) 130 (Supplement 1): 2703.

https://doi.org/10.1182/blood.V130.Suppl_1.2703.2703

Published: 2017

Journal Articles

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Dyantha I. Van Der Lee, BSc., Helena M. Bijen, MSc, Renate S. Hagedoorn, ing., Willy M. Honders, ing., Michel G.D. Kester, ing., Dirk M. van der Steen, ing., Arnoud H. de Ru, ing., Inge Jedema, PhD, Hendrik Veelken, MD PhD, Mirjam H.M. Heemskerk, PhD, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Marieke Griffioen, PhD

Blood (2017) 130 (Supplement 1): 168.

https://doi.org/10.1182/blood.V130.Suppl_1.168.168

Published: 2017

Journal Articles

TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1

Lorenz Jahn, Pleun Hombrink, Renate S. Hagedoorn, Michel G. D. Kester, Dirk M. van der Steen, Tania Rodriguez, Tsvetelina Pentcheva-Hoang, Arnoud H. de Ru, Marjolein P. Schoonakker, Miranda H. Meeuwsen, Marieke Griffioen, Peter A. van Veelen, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk

Blood (2017) 129 (10): 1284–1295.

https://doi.org/10.1182/blood-2016-09-737536

Published: 2017

Includes: Supplemental data

Journal Articles

Whole Transcriptome Sequencing (RNAseq) As a Comprehensive, Cost-Efficient Diagnostic Tool for Acute Myeloid Leukemia

Marieke Griffioen, PhD, Wibowo Arindrarto, MSc, Daniel Borràs, MSc, Saskia A.M.E. van Diessen, BSc, Edith D. van der Meijden, M. Willy Honders, Mariam Alloul, PhD, Inge Jedema, PhD, Wilma G.M. Kroes, PhD, Peter J.M. Valk, PhD, Bart Janssen, PhD, Cornelis A.M. van Bergen, PhD, Szymon M. Kiełbasa, PhD, Jeroen F.J. Laros, PhD, Peter A.C. 't Hoen, PhD, Hendrik Veelken, MD PhD

Blood (2016) 128 (22): 1701.

https://doi.org/10.1182/blood.V128.22.1701.1701

Published: 2016

Journal Articles

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Sascha Kretschmann, Heiko Bruns, PhD, Ursula Schlötzer-Schrehardt, PhD, Andreas Mackensen, MD, Marieke Griffioen, PhD, Anita Kremer

Blood (2016) 128 (22): 3712.

https://doi.org/10.1182/blood.V128.22.3712.3712

Published: 2016

Journal Articles

Antigen-Independent, Autonomous B-Cell Receptor Signaling As a Dominant Candidate Oncogenic Mechanism in ABC DLBCL

Marvyn T. Koning, BSc, Rudolf Übelhart, PhD, Arjen H.G. Cleven, PhD, Willem H. Zoutman, BSc, Sander A.J. van der Zeeuw, BSc, Philip Kluin, MD PhD, Marieke Griffioen, PhD, Cornelis P. Tensen, PhD, Maarten H. Vermeer, MD PhD, Rein Willemze, MD PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, MD PhD, Hassan Jumaa, PhD, Hendrik Veelken, MD PhD

Blood (2016) 128 (22): 778.

https://doi.org/10.1182/blood.V128.22.778.778

Published: 2016

Journal Articles

Primary Mediastinal Large B-Cell Lymphoma Exhibits Autonomous BCR Signaling and Responds to the Second Generation BTK Inhibitor Acalabrutinib

Marvyn T. Koning, BSc, Rudolf Übelhart, PhD, Sander A.J. van der Zeeuw, BSc, Philip Kluin, MD PhD, Marieke Griffioen, PhD, Hans G. Drexler, MD PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, MD PhD, Hassan Jumaa, PhD, Hendrik Veelken, MD PhD

Blood (2016) 128 (22): 4171.

https://doi.org/10.1182/blood.V128.22.4171.4171

Published: 2016

Journal Articles

Endogenous Immunoglobulin-Derived Neoepitopes Are Processed and Form a Sizeable Fraction of the HLA Class I Ligandome of Human Lymphoma Cells

Cornelis A.M. van Bergen, PhD, Dirk M. van der Steen, Michel G.D. Kester, Marvyn T. Koning, BSc, Peter A. van Veelen, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD, Hendrik Veelken, MD PhD, Marcelo A Navarrete, MD PhD

Blood (2016) 128 (22): 914.

https://doi.org/10.1182/blood.V128.22.914.914

Published: 2016

Journal Articles

Massive Parallel Sequencing of Full-Length B-Cell Receptor Sequences Reveals HLA-Dependent Shaping of the B-Cell Immune Repertoire

Marvyn T. Koning, Sander A.J. van der Zeeuw, Marcelo Navarrete, MD, Cornelis A.M. van Bergen, Valeri Nteleah, MSc, Marieke Griffioen, PhD, Szymon M. Kiełbasa, PhD, Hendrik Veelken, MDPhD

Blood (2014) 124 (21): 4143.

https://doi.org/10.1182/blood.V124.21.4143.4143

Published: 2014

Journal Articles

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

Cornelis A.M. van Bergen, Simone A.P. Van Luxemburg-Heijs, Matthijs Eefting, MD, Maria W. Honders, Inge Jedema, PhD, Constantijn J.M. Halkes, MD, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2013) 122 (21): 2014.

https://doi.org/10.1182/blood.V122.21.2014.2014

Published: 2013

Journal Articles

LB-ARHGDIB-1R As Novel Minor Histocompatibility Antigen For Therapeutic Application

Margot J Pont, Willemijn Hobo, PhD, M. Willy Honders, Simone A.P. van Luxemburg-Heijs, Michel G.D. Kester, Cornelis A.M. van Bergen, Harry Dolstra, PhD, J.H. Frederik Falkenburg, MD, PhD, Marieke Griffioen, PhD

Blood (2013) 122 (21): 4465.

https://doi.org/10.1182/blood.V122.21.4465.4465

Published: 2013

NARROW

Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens

Immunotherapy Targeting Mutant Nucleophosmin-1 on Acute Myeloid Leukemia

Large Scale Identification and Validation of 85 New HLA Class I-Restricted Minor Histocompatibility Antigens for Immune Monitoring and Modulation after Allogeneic Stem Cell Transplantation

Broadly Applicable TCR Based Therapy for Multiple Myeloma Targeting the Jchain

Immunotherapy By Targeting CD45 in Mismatched HLA-DP to Treat Patients after Allogeneic Stem Cell Transplantation

Special Anatomical Subtypes of Diffuse Large B-Cell Lymphoma Have Distinct Tumor Microenvironments

Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DM

HLA-DM Mediates Permissiveness of HLA-DPB1 T Cell Epitope Mismatches in Unrelated HCT

Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia

Fusion Transcripts without Corresponding Cytogenetic Abnormalities in Acute Myeloid Leukemia: Implications for AML Pathogenesis

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1

Whole Transcriptome Sequencing (RNAseq) As a Comprehensive, Cost-Efficient Diagnostic Tool for Acute Myeloid Leukemia

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Antigen-Independent, Autonomous B-Cell Receptor Signaling As a Dominant Candidate Oncogenic Mechanism in ABC DLBCL

Primary Mediastinal Large B-Cell Lymphoma Exhibits Autonomous BCR Signaling and Responds to the Second Generation BTK Inhibitor Acalabrutinib

Endogenous Immunoglobulin-Derived Neoepitopes Are Processed and Form a Sizeable Fraction of the HLA Class I Ligandome of Human Lymphoma Cells

Massive Parallel Sequencing of Full-Length B-Cell Receptor Sequences Reveals HLA-Dependent Shaping of the B-Cell Immune Repertoire

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

LB-ARHGDIB-1R As Novel Minor Histocompatibility Antigen For Therapeutic Application

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American Society of Hematology

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American Society of Hematology

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