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Mark Chiang
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Journal Articles

STAT1-mediated interferon signatures associate with preclinical JAK-inhibitor sensitivity in T-cell acute lymphoblastic leukemia

Available to Purchase
Jason Xu, Jonathan H Sussman, Austin Yang, Satoshi Yoshimura, Jianzhong Hu, Changya Chen, Tiffaney L Vincent, Shovik Bandyopadhyay, Elizabeth Y Li, Tristan Lee Lim, Omar Elghawy, Adam Barsouk, Damjan Karanfilovski, Shira L Wald, Gregory M Chen, David Wei Wu, Haley Newman, Alexander Li, Yusha Sun, Chia-Hui Chen, Kathrin Maria Bernt, Brent L. Wood, Stuart Sheldon Winter, Kimberly P. Dunsmore, Elizabeth A. Raetz, Meenakshi Devidas, Stanley B Pounds, Mignon L. Loh, Stephen P Hunger, Mark Chiang, Caroline Diorio, Danika Di Giacomo, Petri Pölönen, Charles G. Mullighan, Jun J Yang, Kai Tan, David Trent Teachey
Journal: Blood
Blood blood.2025028566.
https://doi.org/10.1182/blood.2025028566
Published: 2025
Includes: Supplemental data
Journal Articles

ETS1 Recruits the Canonical Baf Complex to Reactivate the Hematopoietic Stem Cell MYB Enhancer in the T-Cell Leukemia Context

Free
Carea Mullin, Karena Hsijan Lin, Anna McCarter, Elizabeth Choe, Shannon Liang, Qing Wang, Ashley Melnick, Zeel Shukla, Cher Sha, Ashwin Iyer, Rohan Kodgule, Yamei Deng, Felipe Leprevost, Kelly R. Barnett, Daniel Savic, Alexey Nesvizhskii, Russell J. H. Ryan, Mark Chiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 203.
https://doi.org/10.1182/blood-2024-207624
Published: 2024
Journal Articles

Crispri Essentiality Screen Reveals the Essential Enhancers and Oncogenes Comprising the “Regulome” of the Notch-Collaborating Transcription Factor ETS1 in Human T-ALL

Free
Karena Hsijan Lin, Annie Wang, Kailey Lashbrook, Kaitlyn Chan, Elizabeth Choe, Ashwin Iyer, Kelly R. Barnett, Daniel Savic, Russell J. H. Ryan, Mark Chiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4131.
https://doi.org/10.1182/blood-2024-210398
Published: 2024
Journal Articles

The Direct Notch1 Cofactor Zmiz1 Differentially Regulates Notch1 Signals in a Stage-Specific Manner to Preserve Early T-Cell Precursors and Expand Committed T Cells

Free
Qing Wang, Ran Yan, Nancy Pinnell, Yiran Liu, Amparo Serna Alarcon, Jason Qin, Yitong Chen, Erin Kim, Noah Garber, Ivan Maillard, MD PhD, Tomasz Cierpicki, PhD, Mark Chiang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 426.
https://doi.org/10.1182/blood.V128.22.426.426
Published: 2016
Journal Articles

Critical Functions for Notch Dimerization In T Cell Transformation.

Free
Hudan Liu, Ph.D., Anthony Chi, Kelly Arnett, Ph.D., Mark Chiang, MD, PhD, Lanwei Xu, M.D., Olga Shestova, Ph.D., Hongfang Wang, Ph.D., Avinash Bhandoola, M.D., Ph.D., Jon C Aster, MD, PhD, Stephen C. Blacklow, MD, PhD, Warren S. Pear, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3647.
https://doi.org/10.1182/blood.V116.21.3647.3647
Published: 2010
Journal Articles

Deletion-Based Mechanisms of Notch1 Activation In T-ALL: Key Roles for RAG Recombinase and A Conserved Internal Translational Start Site In Notch1 .

Free
Jon C Aster, MD, PhD, Todd D Ashworth, Mark Chiang, MD, PhD, Warren S. Pear, MD, PhD, Stephen Blacklow, Michelle Kelliher, Philippe Kastner, Susan Chan
Journal: Blood
Blood (2010) 116 (21): 3367.
https://doi.org/10.1182/blood.V116.21.3367.3367
Published: 2010
Journal Articles

Identification of a C-Terminal Negative Regulatory Sequence in NOTCH1 That Influences Signal Strength and Leukemogenic Activity.

Free
Mina L. Xu, Mark Chiang, MD, PhD, Woojoong Lee, Warren S. Pear, MD, PhD, Jon C. Aster, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 535.
https://doi.org/10.1182/blood.V106.11.535.535
Published: 2005