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Mark T Drayson, MDPhD
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Journal Articles

Apobec Family Mutational Signatures Are Associated with Poor Prognosis Translocations in Multiple Myeloma

Brian A Walker, PhD, Christopher P Wardell, PhD, Alexander Murison, PhD, Eileen M Boyle, MD, Lorenzo Melchor, PhD, Charlotte Pawlyn, MD, Martin F Kaiser, MD, Dil Begum, BSc, Nasrin Dahir, BSc, Paula Proszek, MSc, David C Johnson, PhD, Ya-Wei Qiang, MD PhD, John Jones, MD, David A Cairns, PhD, Walter Gregory, PhD, Roger G Owen, MD, Gordon Cook, MD, Mark T Drayson, MDPhD, Graham Jackson, MD, Faith E Davies, MD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 723.
https://doi.org/10.1182/blood.V124.21.723.723
Published: 2014
Journal Articles

Mutational Patterns and Copy Number Changes at Diagnosis Are a Powerful Tool to Predict Outcome: Result of the Sequencing Study of 463 Newly Diagnosed Myeloma Trial Patients

Eileen M Boyle, MD, Brian A Walker, PhD, Christopher P Wardell, PhD, Alexander Murison, PhD, Lorenzo Melchor, PhD, Martin F Kaiser, MD, Dil Begum, BSc, Paula Proszek, MSc, Nasrin Dahir, BSc, David C Johnson, PhD, Charlotte Pawlyn, MBBChir, John Jones, MD, Fabio Mirabella, PhD, Annamaria Brioli, Aneta Mikulasova, M.Sc., David A Cairns, PhD, Walter Gregory, PhD, Ana Quartilho, PhD, Mark T Drayson, MDPhD, Nigel Russell, Gordon Cook, MD PhD, Graham H Jackson, MD PhD, Faith E Davies, MD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 637.
https://doi.org/10.1182/blood.V124.21.637.637
Published: 2014
Journal Articles

The Extent of Intra-Clonal Genetic Diversity within the Myeloma Clone Is a Predictive Biomarker of Progression and Outcome after Treatment

Lorenzo Melchor, PhD, Alexander Murison, PhD, Eileen M Boyle, MD, Christopher P Wardell, PhD, John Jones, MD, Martin F Kaiser, MD, Charlotte Pawlyn, MBBChir, David C Johnson, PhD, Dil Begum, BSc, Paula Proszek, MSc, Nasrin Dahir, BSc, David A Cairns, PhD, Walter Gregory, PhD, Roger G Owen, MD, Gordon Cook, MD PhD, Mark T Drayson, MDPhD, Graham H Jackson, MD PhD, Faith E Davies, MD, Brian A Walker, PhD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 640.
https://doi.org/10.1182/blood.V124.21.640.640
Published: 2014
Journal Articles

High Resolution Genome Wide DNA Methylation Analysis in a Large Trial Group Reveals a Novel Epigenetically Defined Subgroup of Myeloma Patients Characterized By Developmental Gene Hypermethylation

Martin F Kaiser, MD, Alexander Murison, PhD, Charlotte Pawlyn, MBBChir, Eileen M Boyle, MD, David C Johnson, PhD, Brian A Walker, PhD, Ping Wu, MBBS, MSc, Dil Begum, BSc, Nasrin Dahir, BSc, Christopher P Wardell, PhD, Paula Proszek, MSc, David A Cairns, PhD, Walter Gregory, PhD, Graham Jackson, MD, Roger G Owen, MD, Gordon Cook, MD PhD, Mark T Drayson, MDPhD, Faith E Davies, MD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2189.
https://doi.org/10.1182/blood.V124.21.2189.2189
Published: 2014
Journal Articles

The Spectrum of Epigenetic Mutations in Myeloma and Their Clinical Impact

Charlotte Pawlyn, MBBChir, Martin F Kaiser, MD, Brian A Walker, PhD, Christopher P Wardell, PhD, Alexander Murison, PhD, David C Johnson, PhD, Lorenzo Melchor, PhD, Eileen M Boyle, MD, John Jones, MD, Dil Begum, BSc, Nasrin Dahir, BSc, Paula Proszek, MSc, David A Cairns, PhD, Walter Gregory, PhD, Gordon Cook, MD, Roger G Owen, MD, Mark T Drayson, MDPhD, Graham Jackson, MD, Faith E Davies, MD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2194.
https://doi.org/10.1182/blood.V124.21.2194.2194
Published: 2014
Journal Articles

Rapid, Robust and Accessible Molecular Profiling of Biologically and Clinically Relevant Copy Number Alterations in Multiple Myeloma from Small Amounts of Tumor DNA

Martin F Kaiser, MD, Paula Proszek, MSc, Dil Begum, BSc, Nasrin Dahir, BSc, Brian A Walker, PhD, Suvi Savola, PhD, Eileen M Boyle, MD, David C Johnson, PhD, David A Cairns, PhD, Walter Gregory, PhD, Graham Jackson, MD, Roger G Owen, MD, Gordon Cook, MD PhD, Mark T Drayson, MDPhD, Faith E Davies, MD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 5168.
https://doi.org/10.1182/blood.V124.21.5168.5168
Published: 2014
Journal Articles

High Throughput Genetic Profiling Using a Robust All-Molecular Diagnostic Approach Is Feasible to Specifically Identify a High Risk Group of Myeloma Patients

Martin F Kaiser, MD, Eileen M Boyle, MD, Brian A Walker, PhD, Charlotte Pawlyn, MBBChir, Dil Begum, BSc, Paula Proszek, MSc, Nasrin Dahir, BSc, David C Johnson, PhD, Suvi Savola, PhD, David A Cairns, PhD, Walter Gregory, PhD, Graham Jackson, MD, Roger G Owen, MD, Gordon Cook, MD PhD, Mark T Drayson, MDPhD, Faith E Davies, MD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 172.
https://doi.org/10.1182/blood.V124.21.172.172
Published: 2014
Journal Articles

Comparison of Kappa & Lambda Freelite to Total Kappa & Lambda Immunoassays for the Detection of Monoclonal Gammopathies, Both As Standalone Tests and Alongside Serum Protein Electrophoresis

Vania T M Hungria, MDPhD, Petros Kampanis, Mark T Drayson, MDPhD, Tim Plant, MD, Edvan de Queiroz Crusoe, MD MsC, Ana Lucia Peres, MD, Priscilla Cury, MD, Manuella Sampaio, MD PhD, Elyara Soares, PhD, Stephen Harding, MDPhD
Journal: Blood
Blood (2014) 124 (21): 5705.
https://doi.org/10.1182/blood.V124.21.5705.5705
Published: 2014
Journal Articles

Minimal Residual Disease (MRD) in Myeloma: Independent Outcome Prediction and Sequential Survival Benefits per Log Tumour Reduction

Andy C Rawstron, BSc, PhD, Walter Gregory, PhD, Ruth M de Tute, Faith E Davies, MD, Susan E Bell, DPhil, Mark T Drayson, MDPhD, Gordon Cook, MD, Graham H Jackson, MD, James A Child, Gareth J. Morgan, MD PhD, Roger G Owen
Journal: Blood
Blood (2014) 124 (21): 3416.
https://doi.org/10.1182/blood.V124.21.3416.3416
Published: 2014