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Journal Articles

Metformin for Treatment of Cytopenias in Children and Young Adults with Fanconi Anemia

Jessica A. Pollard, Elissa M. Furutani, Shanshan Liu, Erica B. Esrick, Laurie Cohen, Jacob Bledsoe, Kun Lu, Maria Jose Ramirez, Jordi Surrallés, Maggie Malsch, Ashley Kuniholm, Ashley Galvin, Myriam Armant, Annette S. Kim, Kaitlyn Ballotti, Lisa Moreau, Yu Zhou, Daria V. Babushok, Farid Boulad, Clinton Carroll, Helge Hartung, Amy Hont, Taizo A. Nakano, Timothy S. Olson, Sei-Gyung K. Sze, Alexis A Thompson, Marcin W. Wlodarski, Towia A Libermann, Alan D. D'Andrea, Markus Grompe, Edie A. Weller, Akiko Shimamura
Journal: Blood
Blood (2021) 138 (Supplement 1): 1102.
https://doi.org/10.1182/blood-2021-153598
Published: 2021
Journal Articles

Replication Stress Response and CDKN1A Engagement Constrain Fetal Hematopoietic Stem Cell Pool Size in Fanconi Anemia

Makiko Mochizuki-Kashio, PhD, Young Me Yoon, Theresa N Menna, BS, Markus Grompe, MD, Peter Kurre, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 107.
https://doi.org/10.1182/blood-2019-125669
Published: 2019
Journal Articles

Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice

Qing-Shuo Zhang, Weiliang Tang, Matthew Deater, Ngoc Phan, Andrea N. Marcogliese, Hui Li, Muhsen Al-Dhalimy, Angela Major, Susan Olson, Raymond J. Monnat, Jr, Markus Grompe
Journal: Blood
Blood (2016) 128 (24): 2774–2784.
https://doi.org/10.1182/blood-2015-11-683490
Published: 2016
Includes: Supplemental data
Journal Articles

Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression

Kevin O'Connor, Sofia Vidal-Cardenas, PhD, Haojian Zhang, PhD, Alfredo Rodriguez, Lisa Moreau, Chunyu Yang, Michael W Epperly, PhD, Markus Grompe, MD, Akiko Shimamura, MD PhD, Joel S. Greenberger, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD
Journal: Blood
Blood (2016) 128 (22): 1039.
https://doi.org/10.1182/blood.V128.22.1039.1039
Published: 2016
Journal Articles

TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, Alix Rousseau, Lisa Moreau, Emily Gaudiano, BS, Joel S Greenberger, MD, Grover C. Bagby, Jr., MD MACP, Jean Soulier, MD PhD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD
Journal: Blood
Blood (2015) 126 (23): 297.
https://doi.org/10.1182/blood.V126.23.297.297
Published: 2015
Journal Articles

Oxymetholone Therapy of Fanconi Anemia Induces Hematopoietic Stem Cell Cycling By Suppressing Osteopontin Transcription

Qingshuo Zhang, PhD, Eric Benedetti, Matthew Deater, Kathryn Schubert, Angela Major, Carl Pelz, Soren Impey, Laura Marquez-Loza, Keaney Rathbun, Shigeaki Kato, PhD, Grover C. Bagby, MD MACP, Markus Grompe, MD
Journal: Blood
Blood (2014) 124 (21): 2949.
https://doi.org/10.1182/blood.V124.21.2949.2949
Published: 2014
Journal Articles

Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, BA, Sofia Vidal-Cardenas, PhD, Abigail Hamilton, BA, Emily Gaudiano, BS, Joel S. Greenberger, MD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D. D'Andrea, MD
Journal: Blood
Blood (2014) 124 (21): 356.
https://doi.org/10.1182/blood.V124.21.356.356
Published: 2014
Journal Articles

Fanconi Anemia: Emerging Therapeutic Opportunities

Markus Grompe, MD, John Postlethwait, Professor, Alan D. D'Andrea, MD, Susan B. Olson, Qingshuo Zhang, Grover C. Bagby, Jr.
Journal: Blood
Blood (2012) 120 (21): SCI-1.
https://doi.org/10.1182/blood.V120.21.SCI-1.SCI-1
Published: 2012
Journal Articles

Fancd2 −/− mice have hematopoietic defects that can be partially corrected by resveratrol

Qing-Shuo Zhang, Laura Marquez-Loza, Laura Eaton, Andrew W. Duncan, Devorah C. Goldman, Praveen Anur, Kevin Watanabe-Smith, R. Keaney Rathbun, William H. Fleming, Grover C. Bagby, Markus Grompe
Journal: Blood
Blood (2010) 116 (24): 5140–5148.
https://doi.org/10.1182/blood-2010-04-278226
Published: 2010
Includes: Supplemental data
Journal Articles

Acute Myeloid Leukemia Cells Fuse with Vascular Endothelium

Azzah Al Masri, Ph.D., Devorah C Goldman, Ph.D., Steven A. Asbaghi, Hilary A. Clark, Ronald P. Leon, Ph.D., Qiuying Liu, Raymond D. Hickey, Markus Grompe, MD, Peter Kurre, MD, William H Fleming, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 504.
https://doi.org/10.1182/blood.V116.21.504.504
Published: 2010
Journal Articles

Natural gene therapy in monozygotic twins with Fanconi anemia

Anuj Mankad, Toshiyasu Taniguchi, Barbara Cox, Yassmine Akkari, R. Keaney Rathbun, Lora Lucas, Grover Bagby, Susan Olson, Alan D'Andrea, Markus Grompe
Journal: Blood
Blood (2006) 107 (8): 3084–3090.
https://doi.org/10.1182/blood-2005-07-2638
Published: 2006
Journal Articles

Myeloid Lineage-Restricted Progenitors Contribute to Vascular Endothelium.

Alexis S. Bailey, Holger Willenbring, Shuguang Jiang, David A. Schroeder, Daniel A. Anderson, Markus Grompe, Melissa H. Wong, William H. Fleming
Journal: Blood
Blood (2005) 106 (11): 2267.
https://doi.org/10.1182/blood.V106.11.2267.2267
Published: 2005
Journal Articles

Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin

Rocio Montes de Oca, Paul R. Andreassen, Steven P. Margossian, Richard C. Gregory, Toshiyasu Taniguchi, XiaoZhe Wang, Scott Houghtaling, Markus Grompe, Alan D. D'Andrea
Journal: Blood
Blood (2005) 105 (3): 1003–1009.
https://doi.org/10.1182/blood-2003-11-3997
Published: 2005
Journal Articles

Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors

Francesco Galimi, Meenakshi Noll, Yoshiyuki Kanazawa, Timothy Lax, Cindy Chen, Markus Grompe, Inder M. Verma
Journal: Blood
Blood (2002) 100 (8): 2732–2736.
https://doi.org/10.1182/blood-2002-04-1245
Published: 2002
Journal Articles

S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

Toshiyasu Taniguchi, Irene Garcia-Higuera, Paul R. Andreassen, Richard C. Gregory, Markus Grompe, Alan D. D'Andrea
Journal: Blood
Blood (2002) 100 (7): 2414–2420.
https://doi.org/10.1182/blood-2002-01-0278
Published: 2002
Journal Articles

Phenotypic correction of Fanconi anemia group C knockout mice

Kimberly A. Gush, Kai-Ling Fu, Markus Grompe, Christopher E. Walsh
Journal: Blood
Blood (2000) 95 (2): 700–704.
https://doi.org/10.1182/blood.V95.2.700
Published: 2000
Journal Articles

In Vivo Selection of Wild-Type Hematopoietic Stem Cells in a Murine Model of Fanconi Anemia

Kevin P. Battaile, Raynard L. Bateman, Derik Mortimer, Jean Mulcahy, R. Keaney Rathbun, Grover Bagby, William H. Fleming, Markus Grompe
Journal: Blood
Blood (1999) 94 (6): 2151–2158.
https://doi.org/10.1182/blood.V94.6.2151
Published: 1999
Journal Articles

DNA Cross-Linker–Induced G2/M Arrest in Group C Fanconi Anemia Lymphoblasts Reflects Normal Checkpoint Function

Michael C. Heinrich, Maureen E. Hoatlin, Amy J. Zigler, Kirsten V. Silvey, Antony C. Bakke, Winifred W. Keeble, Yu Zhi, Carol A. Reifsteck, Markus Grompe, Michael G. Brown, R. Ellen Magenis, Susan B. Olson, Grover C. Bagby, Jr
Journal: Blood
Blood (1998) 91 (1): 275–287.
https://doi.org/10.1182/blood.V91.1.275
Published: 1998
Journal Articles

Molecular Biology of Fanconi Anemia: Implications for Diagnosis and Therapy

Alan D. D'Andrea, Markus Grompe
Journal: Blood
Blood (1997) 90 (5): 1725–1736.
https://doi.org/10.1182/blood.V90.5.1725
Published: 1997
Journal Articles

Inactivation of the Fanconi Anemia Group C Gene Augments Interferon-γ–Induced Apoptotic Responses in Hematopoietic Cells

R. Keaney Rathbun, Gregory R. Faulkner, Marika H. Ostroski, Tracy A. Christianson, Grant Hughes, Gary Jones, Robert Cahn, Richard Maziarz, Gordon Royle, Winifred Keeble, Michael C. Heinrich, Markus Grompe, Paula A. Tower, Grover C. Bagby
Journal: Blood
Blood (1997) 90 (3): 974–985.
https://doi.org/10.1182/blood.V90.3.974
Published: 1997