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Martin Hirst, PhD
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Journal Articles

NUP98-HOXA9 -Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML

Ivan Sloma, PharmD, PhD, Philip Beer, PhD FRCPath, MRCP, Christophe Desterke, PhD, Elizabeth Bulaeva, Misha Bilenky, Michelle Moksa, Kamini Raghuram, Cedric Brimacombe, Karen Lambie, Ali G Turhan, MD PhD, Orianne Wagner-Ballon, MD PhD, Philippe Gaulard, MD PhD, R. Keith Humphries, MD PhD, Martin Hirst, PhD BS, Connie J. Eaves, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4139.
https://doi.org/10.1182/blood-2019-127839
Published: 2019
Journal Articles

Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells

Elizabeth Bulaeva, Davide Pellacani, PhD, Naoto Nakamichi, MD PhD, Philip Beer, MD PhD, Colin Hammond, Alireza Lorzadeh, Michelle Moksa, Annaick Carles, Misha Bilenky, Sylvain Lefort, PhD, Jeremy Shu, Brian T. Wilhelm, PhDBSc, Andrew P. Weng, MD PhD, Martin Hirst, PhD, Connie J. Eaves, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2533.
https://doi.org/10.1182/blood-2019-122768
Published: 2019
Journal Articles

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Manabu Kusakabe, MD PhD, Ann Chong Sun, Kateryna Tyshchenko, Rachel Wong, Aastha Nanda, Claire Shanna, Samuel Gusscott, PhD, Elizabeth Chavez, Alireza Lorzadeh, Alice Zhu, Ainsleigh Hill, Stacy Hung, Scott Brown, Artem Babaian, Xuehai Wang, PhD, Robert Holt, PhD, Christian Steidl, MD, Aly Karsan, MD, R. Keith Humphries, MD PhD, Connie J. Eaves, PhD, Martin Hirst, PhD, Andrew P. Weng, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1322.
https://doi.org/10.1182/blood-2018-99-120120
Published: 2018
Journal Articles

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Jennifer Grants, PhD, Joanna Wegrzyn, PhD, David Knapp, PhD, Tony Hui, Kieran O'Neill, PhD, Jeremy Parker, PhD, Deborah Deng, Mark Boldin, PhD, Martin Hirst, PhD, Connie J. Eaves, PhD, Aly Karsan, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 714.
https://doi.org/10.1182/blood.V130.Suppl_1.714.714
Published: 2017
Journal Articles

NOTCH1 Induces Differential Epigenomic Patterning and Genomic Organization in Fetal Liver- and Adult Bone Marrow-Derived Hematopoietic Progentiors

Vincenzo Giambra, PhD, Sonya H Lam, Miriam Belmonte, Sam Gusscott, Sohrab Salehi, Fong Chun Chan, Robert Kridel, MD MPH, Alireza Lorzadeh, Catherine Hoofd, PhD, Christian Steidl, MD, Connie J. Eaves, PhD, Martin Hirst, PhD, Andrew P. Weng, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3637.
https://doi.org/10.1182/blood.V126.23.3637.3637
Published: 2015
Journal Articles

Preclinical Determination of the Efficacy of Epigenetic Therapy in High Risk Myeloid Disease Using the Zebrafish Model

Adam Deveau, BSc, MSc, Alexander Michael Forrester, BSc, PhD, Andrew J Coombs, BScH, Gretchen S Wagner, BScH, Clemens Grabher, PhD, Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Matthew Mingay, BSc, Martin Hirst, PhD, A. Thomas Look, MD, Jason N. Berman, MD
Journal: Blood
Blood (2014) 124 (21): 436.
https://doi.org/10.1182/blood.V124.21.436.436
Published: 2014
Journal Articles

Genome-Wide Identification of Human Micrornas Located in Leukemia-Associated Genomic Alterations.

Daniel T. Starczynowski, PhD, Ryan Morin, PhD, Andrew McPherson, Martin Hirst, PhD, Marco A. Marra, Ph.D., Wan L Lam, PhD, Aly Karsan, MD
Journal: Blood
Blood (2009) 114 (22): 1287.
https://doi.org/10.1182/blood.V114.22.1287.1287
Published: 2009
Journal Articles

Identification of Mir-145 and Mir-146a as Micrornas Involved in the Pathogenesis of 5q- Syndrome

Daniel T. Starczynowski, PhD, Florian Kuchenbauer, MD, Bob Argiropoulos, PhD, Sandy Sung, Ryan Morin, PhD, Andrew L Muranyi, MSc, Martin Hirst, PhD, Donna E. Hogge, MD, PhD, Marco Marra, PhD, Richard A. Wells, MD, DPhil, Wan Lam, PhD, R. Keith Humphries, MD, PhD, Aly Karsan, MD
Journal: Blood
Blood (2008) 112 (11): 853.
https://doi.org/10.1182/blood.V112.11.853.853
Published: 2008
Journal Articles

Accurate Detection of the microRNA Transcriptome in a Leukemia Progression Model.

Florian Kuchenbauer, MD, Ryan Morin, PhD, Johann Staaf, PhD, Ake Borg, MD, PhD, Bob Agiropoulos, PhD, Allen Delaney, PhD, Thomas Zeng, PhD, Helen Mcdonald, PhD, Martin Hirst, PhD, Carlos Rovira, PhD, Marco Marra, PhD, R. Keith Humphries, MD, PHD
Journal: Blood
Blood (2007) 110 (11): 866.
https://doi.org/10.1182/blood.V110.11.866.866
Published: 2007