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Matthew Eaton
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Journal Articles

SY5609, a Potent and Selective CDK7 Inhibitor, Potentiates BTK Inhibitor Activity in Mantle Cell Lymphoma Preclinical Models

Liv Johannessen, Susan Henry, Priyanka Sawant, Anthony D'Ippolito, Nan Ke, Ariel Lefkowitz, Matthew Eaton, Wojciech Dworakowski, Maria Rosario, Graeme Hodgson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1205.
https://doi.org/10.1182/blood-2021-151411
Published: 2021
Journal Articles

Selection of RARA-Positive Newly Diagnosed Unfit AML Patients with Elevated RARA Gene Expression Enriches for Features Associated with Primary Resistance to Venetoclax and Clinical Response to SY-1425, a Potent and Selective RARα Agonist, Plus Azacitidine

Christopher Fiore, PhD, Michael J. Kelly, MD MPH, MS, Angela Volkert, Li Zhou, PhD, Kate Madigan, MD, Matthew Eaton, PhD, Graeme Hodgson, PhD, David A. Roth, MD, Qing Kang-Fortner, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-137323
Published: 2020
Journal Articles

Sy-1365, a Potent and Selective CDK7 Inhibitor, Exhibits Anti-Tumor Activity in Preclinical Models of Hematologic Malignancies, and Demonstrates Interactions with the BCL-XL/BCL2 Mitochondrial Apoptosis Signaling Pathway in Leukemia

Graeme Hodgson, PhD, Liv Johannessen, PhD, Nisha Rajagopal, PhD, Shanhu Hu, PhD, David Orlando, PhD, Matthew Eaton, PhD, Michael McKeown, PhD, Jeffrey W. Tyner, PhD, Stephen E Kurtz, PhD, Kevin Sprott, PhD, Christian Fritz, PhD, Emmanuelle Di Tomaso, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2651.
https://doi.org/10.1182/blood.V130.Suppl_1.2651.2651
Published: 2017
Journal Articles

Discovery and Characterization of Super-Enhancer-Associated Dependencies in Acute Myeloid Leukemia

Michael Ryan Corces-Zimmerman, BA, Matthew Eaton, PhD, Jeremy Lopez, BS, Nan Ke, BS, Christian Fritz, PhD, Eric Olson, PhD, Ravi Majeti, MD PhD, Jakob Loven, PhD
Journal: Blood
Blood (2014) 124 (21): 3539.
https://doi.org/10.1182/blood.V124.21.3539.3539
Published: 2014