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Journal Articles

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

Blood (2020) 136 (Supplement 1): 32–33.

https://doi.org/10.1182/blood-2020-140317

Published: 2020

Journal Articles

Mutant TRP53-R172H Has Gain-of-Function or Dominant-Negative Effects in Response to Different Hematopoietic Stressors in Mice

Tanzir Ahmed, PhD, Tuoen Liu, MD PhD, Michael O. Alberti, MDPhD, Brian Wadugu, PhD, Matthew Ndonwi, PhD, Sarah Grieb, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-141091

Published: 2020

Journal Articles

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Andrew J Menssen, BA, Ajay Khanna, Christopher A Miller, PhD, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Michelle O'Laughlin, Catrina Fronick, BS, Robert Fulton, MS, Kimberly J Brendel, Sharon E Heath, Peter Westervelt, MDPhD, John F. DiPersio, MD PhD, Daniel C. Link, MD, Meagan A. Jacoby, Eric Duncavage, MD, Timothy J Ley, MD, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-140394

Published: 2020

Journal Articles

Creating a Variant Database for the American Society of Hematalogy By Consensus Variant Classification of Common Genes Associated with Hematologic Malignancies

Niroshan Nadarajah, Alex Wagner, PhD, Rafael Bejar, MD PhD, Mark Ewalt, MD, Annette S. Kim, MD, Michelle M. Le Beau, PhD, Xiaotu Ma, PhD, Manja Meggendorfer, PhD, Jamile M. Shammo, MD, Gabriella Ryan, Alexa J. Siddon, MD, David P. Steensma, MD, Matthew J. Walter, MD, Ahmet Zehir, PhD, Jinghui Zhang, PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-141204

Published: 2020

Journal Articles

Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study

Blood (2019) 134 (Supplement_1): 4271.

https://doi.org/10.1182/blood-2019-126978

Published: 2019

Journal Articles

Mutant U2AF1 S34F and U2AF1 Q157P Induce Distinct RNA Splicing and Hematopoietic Phenotypes In Vivo

Michael O. Alberti, MD PhD, Meng'ou Zhu, BS, Sridhar Nonavinkere Srivatsan, MS, Tanzir Ahmed, PhD, Jin J. Shao, Brian Wadugu, BA, Cara Lunn Shirai, PhD, Matthew J. Walter, MD

Blood (2019) 134 (Supplement_1): 770.

https://doi.org/10.1182/blood-2019-123892

Published: 2019

Journal Articles

The Role of Transcription Factor and Signaling Gene Mutations in the Clonal Evolution of MDS to Secondary AML

Andrew E Menssen, BA, Christopher A Miller, PhD, Ajay J Khanna, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Kimberly J Brendel, Sharon E Heath, Eric J. Duncavage, MD, Matthew J. Walter, MD

Blood (2018) 132 (Supplement 1): 4338.

https://doi.org/10.1182/blood-2018-99-119798

Published: 2018

Journal Articles

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

Blood (2018) 132 (Supplement 1): 5277.

https://doi.org/10.1182/blood-2018-99-114979

Published: 2018

Journal Articles

Diagnosis of Myelodysplastic Syndromes and Related Conditions: Rates of Discordance between Local and Central Review in the NHLBI MDS Natural History Study

Ling Zhang, MD, Donald M Stablein, PhD, Pearlie Epling-Burnette, PhD PharmD, Alexandra M. Harrington, MDMT(ASCP), Lynn C. Moscinski, MD, Steven Kroft, MD, Amy E. DeZern, MD, Tareq Al Baghdadi, MD, Jane Jijun Liu, MD, Matthew J. Walter, MD, Rafael Bejar, MD PhD, Edward J. Gorak, DO, MBA, MS, Rami S. Komrokji, MD, Gregory A. Abel, MD MPH, Bart L Scott, MD, Steven D. Gore, MD, Mikkael A. Sekeres, MD MS

Blood (2018) 132 (Supplement 1): 4370.

https://doi.org/10.1182/blood-2018-99-116629

Published: 2018

Journal Articles

U2AF1(S34F) Mutant Hematopoietic Cells Require Expression of Wild-Type U2af1 for Survival

Brian Wadugu, BA, Amanda Heard, Joseph Bradley, BS, Matthew Ndonwi, PhD, Jin J Shao, Matthew J. Walter, MD

Blood (2018) 132 (Supplement 1): 941.

https://doi.org/10.1182/blood-2018-99-110836

Published: 2018

Journal Articles

Cellular Stressors Contribute to the Expansion of Multiple Hematopoietic Clones of Varying Leukemic Potential

Blood (2017) 130 (Supplement 1): 469.

https://doi.org/10.1182/blood.V130.Suppl_1.469.469

Published: 2017

Journal Articles

Subclonal Evolution Characterizes MDS Disease Progression Following Allogeneic Stem Cell Transplant

Meagan Jacoby, MD PhD, Eric J. Duncavage, MD, Gue Su Chang, PhD, Christopher A Miller, PhD, Jin Shao, Kevin Elliot, Joshua Robinson, Robert S Fulton, Catrina Fronick, Michelle O'Laughlin, Daniel C. Link, MD, John F DiPersio, MD PhD, Peter Westervelt, MDPhD, Timothy James J Ley, MD, Timothy Aaron Graubert, MD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 4232.

https://doi.org/10.1182/blood.V130.Suppl_1.4232.4232

Published: 2017

Journal Articles

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Molly A Smith, Gaurav Choudhary, PhD, Andrea Pellagatti, PhD, Kwangmin Choi, PhD, Tushar Damodar Bhagat, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, Maria Elena S Sampson, Shanisha Gordon, Dagny Von Ahrens, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Robert Booher, PhD, Jacqueline Boultwood, PhD, Amit Verma, MD, Daniel Starczynowski, PhD

Blood (2017) 130 (Supplement 1): 785.

https://doi.org/10.1182/blood.V130.Suppl_1.785.785

Published: 2017

Journal Articles

Haploinsufficiency of Multiple Genes on Del(5q) Cooperate to Induce B Cell Abnormalities in Mice

Tanzir Ahmed, PhD, Tuoen Liu, MD PhD, Kilannin Krysiak, PhD, Matthew Ndonwi, PhD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 2947.

https://doi.org/10.1182/blood.V130.Suppl_1.2947.2947

Published: 2017

Journal Articles

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Blood (2017) 130 (Supplement 1): 2678.

https://doi.org/10.1182/blood.V130.Suppl_1.2678.2678

Published: 2017

Journal Articles

Germline Tissues and DNA Sequencing Analysis Methods for Optimal Somatic Variant Detection in Myelodysplastic Syndrome (MDS)

Eric Padron, MD, Jamie Teer, PhD, Markus Christian Ball, PhD, Jeffrey S Painter, BS, Rami S. Komrokji, MD, Ling Zhang, MD, Lynn C. Moscinski, MD, Mikkael A. Sekeres, MD MS, Steven D. Gore, MD, Rafael Bejar, MD PhD, Matthew J. Walter, MD, Pearlie Epling-Burnette, PhD PharmD

Blood (2017) 130 (Supplement 1): 1685.

https://doi.org/10.1182/blood.V130.Suppl_1.1685.1685

Published: 2017

Journal Articles

Normal Hematopoiesis Is Dependent on the Expression of U2af1, a Spliceosome Gene Commonly Mutated in MDS

Brian Wadugu, BA, Amanda Heard, Joseph Bradley, BS, Matthew Ndonwi, PhD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 3747.

https://doi.org/10.1182/blood.V130.Suppl_1.3747.3747

Published: 2017

Journal Articles

Loss of Toll-like Receptor 2 Results in Accelerated Leukemogenesis in the NUP98-HOXD13 Mouse Model of MDS

Darlene A. Monlish, PhD, Sima T. Bhatt, MD, Eric J. Duncavage, MD, Zev J. Greenberg, BS, John L. Keller, BS, Matthew J. Walter, MD, Laura G. Schuettpelz, MD PhD

Blood (2017) 130 (Supplement 1): 48.

https://doi.org/10.1182/blood.V130.Suppl_1.48.48

Published: 2017

Journal Articles

Ultra-Deep Sequencing As a Predictive Tool for MDS Progression after Allogeneic Hematopoietic Cell Transplant

Eric J. Duncavage, MD, Meagan Jacoby, MD PhD, Gue Su Chang, PhD, Christopher A Miller, PhD, Natasha Edwin, MD, Geoffrey L. Uy, MD, Joshua Robinson, Haley J Abel, PhD, Jin Shao, Kevin Elliot, Robert Fulton, Catrina Fronick, Michelle O'Laughlin, John F DiPersio, MD PhD, Timothy J Ley, MD, Kathryn Trinkaus, PhD, Timothy Aaron Graubert, MD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 1669.

https://doi.org/10.1182/blood.V130.Suppl_1.1669.1669

Published: 2017

Journal Articles

Spliceosomal Mutations Induce R Loop-Associated ATR Signaling

Wan Yee Leong, PhD, Hai Dang Nguyen, PhD, Weiling Li, PhD, Matthew J. Walter, MD, Lee Zou, PhD, Timothy A. Graubert, MD

Blood (2017) 130 (Supplement 1): 116.

https://doi.org/10.1182/blood.V130.Suppl_1.116.116

Published: 2017

NARROW

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

Mutant TRP53-R172H Has Gain-of-Function or Dominant-Negative Effects in Response to Different Hematopoietic Stressors in Mice

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Creating a Variant Database for the American Society of Hematalogy By Consensus Variant Classification of Common Genes Associated with Hematologic Malignancies

Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study

Mutant U2AF1 S34F and U2AF1 Q157P Induce Distinct RNA Splicing and Hematopoietic Phenotypes In Vivo

The Role of Transcription Factor and Signaling Gene Mutations in the Clonal Evolution of MDS to Secondary AML

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

Diagnosis of Myelodysplastic Syndromes and Related Conditions: Rates of Discordance between Local and Central Review in the NHLBI MDS Natural History Study

U2AF1(S34F) Mutant Hematopoietic Cells Require Expression of Wild-Type U2af1 for Survival

Cellular Stressors Contribute to the Expansion of Multiple Hematopoietic Clones of Varying Leukemic Potential

Subclonal Evolution Characterizes MDS Disease Progression Following Allogeneic Stem Cell Transplant

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Haploinsufficiency of Multiple Genes on Del(5q) Cooperate to Induce B Cell Abnormalities in Mice

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Germline Tissues and DNA Sequencing Analysis Methods for Optimal Somatic Variant Detection in Myelodysplastic Syndrome (MDS)

Normal Hematopoiesis Is Dependent on the Expression of U2af1, a Spliceosome Gene Commonly Mutated in MDS

Loss of Toll-like Receptor 2 Results in Accelerated Leukemogenesis in the NUP98-HOXD13 Mouse Model of MDS

Ultra-Deep Sequencing As a Predictive Tool for MDS Progression after Allogeneic Hematopoietic Cell Transplant

Spliceosomal Mutations Induce R Loop-Associated ATR Signaling

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American Society of Hematology

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American Society of Hematology

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