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Journal Articles

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Blood (2021) 138 (Supplement 1): 800.

https://doi.org/10.1182/blood-2021-148645

Published: 2021

Journal Articles

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Andrew J Menssen, BA, Ajay Khanna, Christopher A Miller, PhD, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Michelle O'Laughlin, Catrina Fronick, BS, Robert Fulton, MS, Kimberly J Brendel, Sharon E Heath, Peter Westervelt, MDPhD, John F. DiPersio, MD PhD, Daniel C. Link, MD, Meagan A. Jacoby, Eric Duncavage, MD, Timothy J Ley, MD, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-140394

Published: 2020

Journal Articles

Comparison of Deep Whole Exome Versus Targeted Gene Sequencing for Assessment of Persistent Molecular Disease in Acute Myeloid Leukemia Samples

Michael Slade, MDMS, Michelle O'Laughlin, Robert S Fulton, Eric J. Duncavage, MD, Timothy J Ley, MD, Meagan A. Jacoby, MD, David H Spencer, MD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-133279

Published: 2020

Journal Articles

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

Blood (2018) 132 (Supplement 1): 5277.

https://doi.org/10.1182/blood-2018-99-114979

Published: 2018

Journal Articles

Subclonal Evolution Characterizes MDS Disease Progression Following Allogeneic Stem Cell Transplant

Meagan Jacoby, MD PhD, Eric J. Duncavage, MD, Gue Su Chang, PhD, Christopher A Miller, PhD, Jin Shao, Kevin Elliot, Joshua Robinson, Robert S Fulton, Catrina Fronick, Michelle O'Laughlin, Daniel C. Link, MD, John F DiPersio, MD PhD, Peter Westervelt, MDPhD, Timothy James J Ley, MD, Timothy Aaron Graubert, MD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 4232.

https://doi.org/10.1182/blood.V130.Suppl_1.4232.4232

Published: 2017

Journal Articles

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Blood (2017) 130 (Supplement 1): 2678.

https://doi.org/10.1182/blood.V130.Suppl_1.2678.2678

Published: 2017

Journal Articles

Ultra-Deep Sequencing As a Predictive Tool for MDS Progression after Allogeneic Hematopoietic Cell Transplant

Eric J. Duncavage, MD, Meagan Jacoby, MD PhD, Gue Su Chang, PhD, Christopher A Miller, PhD, Natasha Edwin, MD, Geoffrey L. Uy, MD, Joshua Robinson, Haley J Abel, PhD, Jin Shao, Kevin Elliot, Robert Fulton, Catrina Fronick, Michelle O'Laughlin, John F DiPersio, MD PhD, Timothy J Ley, MD, Kathryn Trinkaus, PhD, Timothy Aaron Graubert, MD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 1669.

https://doi.org/10.1182/blood.V130.Suppl_1.1669.1669

Published: 2017

Journal Articles

Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

Blood (2017) 129 (10): 1397–1401.

https://doi.org/10.1182/blood-2016-10-745273

Published: 2017

Includes: Supplemental data

Journal Articles

Exome Sequencing of Hodgkin's and Non-Hodgkin Composite Lymphomas Identifies Shared Somatic Mutations Indicative of Common Founding Precursors

Felicia Gomez, PhD, Matthew Matlock, BA, Kilannin Krysiak, PhD, Yi-Shan Lee, MD, Eric J. Duncavage, MD, Michelle O'Laughlin, BS, Malachi Griffith, PhD, Todd A Fehniger, MD PhD, Lukas D. Wartman, MD, Obi L. Griffith, PhD

Blood (2016) 128 (22): 5285.

https://doi.org/10.1182/blood.V128.22.5285.5285

Published: 2016

Journal Articles

Clonal Evolution Revealed By Exome Sequencing in a Case of Primary Myelofibrosis Associated with Subsequent Development of Aggressive Systemic Mastocytosis/Mast Cell Leukemia

Stephen T. Oh, MD PhD, Christopher A. Miller, PhD, Yevgeniy Gindin, PhD, Taylor M. Brost, Jason Chan, MD PhD, Mary C. Fulbright, Daniel A.C. Fisher, PhD, Eric J. Duncavage, MD, Michelle O'Laughlin, Malachi Griffith, PhD, Obi L. Griffith, PhD, Lukas D. Wartman, MD

Blood (2016) 128 (22): 5496.

https://doi.org/10.1182/blood.V128.22.5496.5496

Published: 2016

Journal Articles

Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant

Meagan A. Jacoby, MD PhD, Eric J. Duncavage, MD, Gue Su Chang, PhD, Christopher A. Miller, PhD, Jin Shao, Kevin Elliott, Robert S. Fulton, PhD, Catrina Fronick, Michelle O'Laughlin, Daniel C. Link, MD, John F DiPersio, MD PhD, Peter Westervelt, MD PhD, Timothy J. Ley, MD, Timothy A. Graubert, MD, Matthew J. Walter, MD, Richard K Wilson, PhD

Blood (2016) 128 (22): 5506.

https://doi.org/10.1182/blood.V128.22.5506.5506

Published: 2016

Journal Articles

Rare Pre-Existing MDS Subclones Contribute to Secondary AML Progression

Eric J. Duncavage, MD, Meagan A. Jacoby, MD PhD, Chris Miller, PhD, Gue Su Chang, PhD, Jin Shao, Kevin Elliot, Catrina Fronick, Michelle O'Laughlin, Robert Fulton, PhD, Richard K Wilson, PhD, Timothy A. Graubert, MD, Matthew J. Walter, MD

Blood (2016) 128 (22): 959.

https://doi.org/10.1182/blood.V128.22.959.959

Published: 2016

Journal Articles

Deleterious Germline Mutations in Telomere Maintenance Genes Identified in a Subset of Patients with Myelodysplastic Syndrome and Idiopathic Pulmonary Fibrosis

Kilannin Krysiak, PhD, Meagan A. Jacoby, MD PhD, Zachary L. Skidmore, MS, Arpad M. Danos, PhD, Michelle O'Laughlin, BS, Eric J. Duncavage, MD, Matthew J. Walter, MD, Malachi Griffith, PhD, Obi L. Griffith, PhD, Lukas D. Wartman, MD

Blood (2016) 128 (22): 4306.

https://doi.org/10.1182/blood.V128.22.4306.4306

Published: 2016

Journal Articles

Specific Patterns of DNA Remethylation in the Bone Marrow Cells of Dnmt3a Deficient Mice after Induced Expression of Wild Type Human DNMT3A

Shamika Ketkar-Kulkarni, Angela Maria Verdoni, PhD, Nichole Helton, Christopher B Cole, Celia Venezia, Mieke Hoock, Catrina Fronick, Michelle O'Laughlin, Robert S. Fulton, PhD, David Spencer, MDPhD, Timothy J. Ley, MD

Blood (2015) 126 (23): 433.

https://doi.org/10.1182/blood.V126.23.433.433

Published: 2015

Journal Articles

Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy

Blood (2015) 126 (23): 610.

https://doi.org/10.1182/blood.V126.23.610.610

Published: 2015

Journal Articles

Detection of Clonal Hematopoiesis in Cytopenic Patients Using Targeted Sequencing

Eric J. Duncavage, MD, Jennifer O'Brien, MDPhD, Kiran R. Vij, MD, Chris A Miller, PhD, Jin Shao, Meagan A. Jacoby, MD PhD, Robert S. Fulton, PhD, Sharon Heath, Megan Janke, Catrina C. Fronick, Michelle O'Laughlin, Richard K Wilson, PhD, Timothy J. Ley, MD, Matthew J. Walter, MD

Blood (2015) 126 (23): 1654.

https://doi.org/10.1182/blood.V126.23.1654.1654

Published: 2015

Journal Articles

Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia

Blood (2015) 126 (22): 2484–2490.

https://doi.org/10.1182/blood-2015-04-641100

Published: 2015

Includes: Supplemental data

Journal Articles

Whole-Genome Bisulfite Sequencing of Primary AML Cells with the DNMT3A R882H Mutation Identifies Regions of Focal Hypomethylation That Are Associated with Open Chromatin

David H. Spencer, MDPhD, Bilal Al-Khalil, David Russler-Germain, Tamara Lamprecht, Nicole Havey, Robert S. Fulton, Michelle O'Laughlin, BS, Catrina Fronick, Richard K. Wilson, PhD, Timothy J. Ley, MD

Blood (2014) 124 (21): 608.

https://doi.org/10.1182/blood.V124.21.608.608

Published: 2014

Journal Articles

Complete Sequencing and Comparison of 12 Normal Karyotype M1 AML Genomes with 12 t(15;17) Positive M3-APL Genomes

Blood (2011) 118 (21): 404.

https://doi.org/10.1182/blood.V118.21.404.404

Published: 2011

Journal Articles

Mutations In the DNA Methyltransferase Gene DNMT3A Are Highly Recurrent In Patients with Intermediate Risk Acute Myeloid Leukemia, and Predict Poor Outcomes

Timothy J Ley, MD, Li Ding, PhD, Matthew J. Walter, MD, Michael D. McLellan, BS, Tamara Lamprecht, BS, David E. Larson, PhD, Cyriac Kandoth, PhD, Jacqueline E. Payton, MD, PhD, Jack Baty, BA, John S. Welch, MD, PhD, Christopher C. Harris, BS, Cheryl F. Lichti, PhD, R. Reid Townsend, MD, Robert S. Fulton, MS, David J. Dooling, PhD, Daniel C. Koboldt, MS, Heather Schmidt, BS, Qunyuan Zhang, PhD, John R. Osborne, BS, Ling Lin, MS, Michelle O'Laughlin, BS, Joshua F. McMichael, BS, Kim D. Delehaunty, BA, Sean D. McGrath, MS, Lucinda A. Fulton, MS, Vincent J. Magrini, PhD, Tammi L. Vickery, BS, Jasreet Hundal, MS, Lisa L. Cook, Joshua J. Conyers, Gary W. Swift, BS, Jerry P. Reed, MS, Patricia A. Alldredge, MS, Todd Wylie, BS, Jason Walker, BA, BS, Joelle Kalicki-Veizer, BS, Mark A. Watson, MD, PhD, Sharon Heath, William D. Shannon, PhD, Nobish Varghese, MS, Rakesh Nagarajan, MD, PhD, Peter Westervelt, MD, PhD, Michael H. Tomasson, MD, Daniel C. Link, MD, Timothy A. Graubert, MD, John F. DiPersio, MD, PhD, Elaine R. Mardis, PhD, Richard K. Wilson, PhD

Blood (2010) 116 (21): 99.

https://doi.org/10.1182/blood.V116.21.99.99

Published: 2010

NARROW

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Comparison of Deep Whole Exome Versus Targeted Gene Sequencing for Assessment of Persistent Molecular Disease in Acute Myeloid Leukemia Samples

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

Subclonal Evolution Characterizes MDS Disease Progression Following Allogeneic Stem Cell Transplant

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Ultra-Deep Sequencing As a Predictive Tool for MDS Progression after Allogeneic Hematopoietic Cell Transplant

Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

Exome Sequencing of Hodgkin's and Non-Hodgkin Composite Lymphomas Identifies Shared Somatic Mutations Indicative of Common Founding Precursors

Clonal Evolution Revealed By Exome Sequencing in a Case of Primary Myelofibrosis Associated with Subsequent Development of Aggressive Systemic Mastocytosis/Mast Cell Leukemia

Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant

Rare Pre-Existing MDS Subclones Contribute to Secondary AML Progression

Deleterious Germline Mutations in Telomere Maintenance Genes Identified in a Subset of Patients with Myelodysplastic Syndrome and Idiopathic Pulmonary Fibrosis

Specific Patterns of DNA Remethylation in the Bone Marrow Cells of Dnmt3a Deficient Mice after Induced Expression of Wild Type Human DNMT3A

Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy

Detection of Clonal Hematopoiesis in Cytopenic Patients Using Targeted Sequencing

Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia

Whole-Genome Bisulfite Sequencing of Primary AML Cells with the DNMT3A R882H Mutation Identifies Regions of Focal Hypomethylation That Are Associated with Open Chromatin

Complete Sequencing and Comparison of 12 Normal Karyotype M1 AML Genomes with 12 t(15;17) Positive M3-APL Genomes

Mutations In the DNA Methyltransferase Gene DNMT3A Are Highly Recurrent In Patients with Intermediate Risk Acute Myeloid Leukemia, and Predict Poor Outcomes

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American Society of Hematology

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ASH Publications

American Society of Hematology

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