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Journal Articles

Dasatinib Once-Daily Dose Regimen Provides Robust Anti-Leukemic Activity While Avoiding Suppression of T Cell Activation.

Gary L Schieven, Rosemary Zhang, Sidney Pitt, Kelly McGlinchey, Krista Menard, Richard Smykla, Vojkan Susulic, Mei-Li Wen, Amy Wiebesiek, Robert Townsend, Francis Y. Lee
Journal: Blood
Blood (2009) 114 (22): 2198.
https://doi.org/10.1182/blood.V114.22.2198.2198
Published: 2009
Journal Articles

Quiescent Chronic Myelogenous Leukemia (CML) Cells Are Resistant to BCR-ABL Inhibitors but Preferentially Sensitive to BMS-214662, a Farnesyltransferase Inhibitor (FTI) with Unique Quiescent-Cell Selective Cytotoxicity.

Francis Y. Lee, PhD, Mei-Li Wen, M.Sc., Amy Camuso, B.Sc, Stephen Castenada, B.Sc, Krista Fager, M.Sc., Christine Flefleh, B.Sc, Ivan Inigo, B.Sc, Roger Luo, PhD, David Kan, B.Sc, Veeraswamy Manne, PhD, Kelly McGlinchey, B.Sc, Richard Smykla, B.Sc, Roberto Weinmann, PhD, Robert Kramer, PhD
Journal: Blood
Blood (2005) 106 (11): 1993.
https://doi.org/10.1182/blood.V106.11.1993.1993
Published: 2005
Journal Articles

Dasatinib (BMS-354825) Overcomes Multiple Mechanisms of Imatinib Resistance in Chronic Myeloid Leukemia (CML).

Francis Y. Lee, PhD, Mei-Li Wen, M.Sc., Rajeev Bhide, PhD, Amy Camuso, B.Sc, Stephen Castenada, B.Sc, Krista Fager, B.Sc, Christine Flefleh, B.Sc, Ivan Inigo, B.Sc, David Kan, B.Sc, Roger Luo, PhD, Kelly McGlinchey, B.Sc, Richard Smykla, B.Sc, Robert Wild, PhD, Robert Borzilleri, PhD, Louis Lombardo, PhD
Journal: Blood
Blood (2005) 106 (11): 1994.
https://doi.org/10.1182/blood.V106.11.1994.1994
Published: 2005
Journal Articles

Pharmacokinetics- and Pharmacodynamics-Guided Optimization of the Dose and Treatment Schedule for the Dual SRC/ABL Inhibitor BMS-354825.

Feng Roger Luo, Ph.D., Zheng Yang, Ph.D., Amy Camuso, B.S., Richard Smykla, B.S., Stephen Castenada, B.S., Christine Flefleh, B.S., Krista Fager, M.S., Ivan Inigo, B.S., David Kan, B.S., Kelly McGlinchey, B.S., Mei-Li Wen, M.S., Robert Wild, Ph.D., Robert Borzilleri, Ph.D., Louis Lombardo, Ph.D., Robert Kramer, Ph.D., Francis Y. Lee, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 1987.
https://doi.org/10.1182/blood.V104.11.1987.1987
Published: 2004
Journal Articles

BMS-354825, a Dual SRC/ABL Kinase Inhibitor, Displays Potent Anti-Tumor Activity in a Model of Intracranial CML Growth.

Robert Wild, Ph.D., Stephen Castaneda, B.S., Christine Flefleh, B.S., Krista Fager, B.S., Ivan Inigo, B.S., David Kan, B.S., Richard Smykla, B.S., Amy Camuso, B.S., Kelly McGlinchey, B.S., Mei-Li Wen, B.S., Feng Roger Luo, Ph.D., Robert Borzilleri, Ph.D., Louis Lombardo, Ph.D., Robert Kramer, Ph.D., Francis Y. Lee, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 1988.
https://doi.org/10.1182/blood.V104.11.1988.1988
Published: 2004