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Michael A Rieger, PhD
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Journal Articles

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Lorenz Bastian, Michael P Schroeder, PhD, Cornelia Eckert, PhD, Cornelia Schlee, Jutta Ortiz Tanchez, Sebastian Kämpf, Dimitrios L. Wagner, Veronika Schulze, Konstandina Isaakidis, Alva Rani James, Thomas Burmeister, Stefan Schwartz, MD, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Jochen Hecht, PhD, Philipp A. Greif, MD, Michael A. Rieger, PhD, Monika Brüggemann, MD, Nicola Goekbuget, MD, Carsten Müller-Tidow, Hubert Serve, Martin Neumann, Claudia D. Baldus, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2713.
https://doi.org/10.1182/blood.V130.Suppl_1.2713.2713
Published: 2017
Journal Articles

Heterotrimeric G-Proteins Are Indispensable for FLT3-ITD autophosphorylation and Oncogenic Function

Maike Rehage, PhD, Susanne Wingert, PhD, Nadine Haetscher, PhD, Sabrina Bothur, Hubert Serve, MD, Manuel Grez, PhD, Joachim Schwaeble, MD, Michael A Rieger, PhD
Journal: Blood
Blood (2016) 128 (22): 2712.
https://doi.org/10.1182/blood.V128.22.2712.2712
Published: 2016
Journal Articles

Exploring the Function of Sestrin/Gator As Novel Regulators of Hematopoiesis

Nina Kurrle, PhD, Frank Schnütgen, PhD, Juliana Heidler, PhD, Ina Poser, PhD, Frank Wempe, PhD, Diego Yepes, PhD, Ilka Wittig, PhD, Thomas Oellerich, MD, Michael A Rieger, PhD, Harald von Melchner, MD PhD, Hubert Serve, MD
Journal: Blood
Blood (2016) 128 (22): 1484.
https://doi.org/10.1182/blood.V128.22.1484.1484
Published: 2016
Journal Articles

Multi-Genomics of Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Reveals Three Distinct Genetic Clusters Characterized By Different Alterations

Michael P Schroeder, PhD, Martin Neumann, MD, Cornelia Eckert, PhD, Lorenz Bastian, MD, Alva Rani James, Nicola Gökbuget, MD, Cornelia Schlee, Jutta Ortiz Tanchez, Konstandina Isaakidis, Stefan Schwartz, MD, Thomas Burmeister, MD, Dieter Hoelzer, MD, Heike Pfeiffer, MD, Michael A Rieger, PhD, Stefanie Göllner, PhD, Thomas Oellerich, MD, Diego Yepes, PhD, Renate Kirschner-Schwabe, PhD, Monika Brüggemann, MD PhD, Carsten Müller-Tidow, Hubert Serve, MD, Claudia D. Baldus, MD
Journal: Blood
Blood (2016) 128 (22): 453.
https://doi.org/10.1182/blood.V128.22.453.453
Published: 2016
Journal Articles

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling By Suppression of Mir-146a in Acute Myeloid Leukemia

Sebastian Mohr, Carmen Doebele, PhD, Tobias Berg, MD, Federico Comoglio, PhD, Julia Beck, PhD, Gabriela Alexe, PhD, Jasmin Corso, Hanibal Bohnenberger, MD, Philipp Stroebel, MD, Astrid Wachter, Tim Beissbarth, PhD, Frank Schnuetgen, PhD, Nadine Haetscher, PhD, Stefanie Goellner, PhD, Arefeh Rouhi, PhD, Lars Palmqvist, MD PhD, Michael A Rieger, PhD, Carsten Mueller-Tidow, MD, Florian Kuchenbauer, Ekkehardt Schuetz, MD, Henning Urlaub, PhD, Kimberly Stegmaier, MD, R. Keith Humphries, MD PhD, Hubert Serve, MD, Thomas Oellerich, MD
Journal: Blood
Blood (2016) 128 (22): 1533.
https://doi.org/10.1182/blood.V128.22.1533.1533
Published: 2016
Journal Articles

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

Razan Jammal, Kathrin Krowiorz, Nadine Haetscher, PhD, Stephan Emmrich, PhD MSc, Arefeh Rouhi, PhD, Michael Heuser, MD, Sabrina Bothur, Lars Bullinger, MD, Konstanze Döhner, Courteney Lai, Tobias Maetzig, Askar Obulkasim, Vera Martins, PhD, Medhanie A. Mulaw, Jun.-Prof. Dr., Jan Stary, MD D.Sc., Andre Baruchel, MD, Valerie De Haas, MD PhD, Dirk Reinhardt, MD PhD, Hartmut Döhner, MD, Jens Ruschmann, Michel Zwaan, Marry van den Heuvel-Eibrink, Dirk Heckl, PhD, Maarten Fornerod, PhD, R. Keith Humphries, MD PhD, Michael A Rieger, PhD, Florian Kuchenbauer, Jan-Henning Klusmann, MD
Journal: Blood
Blood (2016) 128 (22): 1534.
https://doi.org/10.1182/blood.V128.22.1534.1534
Published: 2016
Journal Articles

The Gadd45 Family As Mediators of Hematopoietic Stem Cell Differentiation - from Genotoxic Stress to Cytokine-Induced Differentiation

Susanne Wingert, MSc, Frederic B Thalheimer, PhD, Nadine Haetscher, MSc, Maike Rehage, PhD, Hubert Serve, MD, Timm Schroeder, PhD, Michael A. Rieger, PhD
Journal: Blood
Blood (2015) 126 (23): 1188.
https://doi.org/10.1182/blood.V126.23.1188.1188
Published: 2015
Journal Articles

STAT5-Regulated miRNA193b Controls Hematopoietic Stem and Progenitor Cell Expansion By Fine Tuning Cytokine Signaling

Nadine Haetscher, Yonatan D Feuermann, PhD, Susanne Wingert, Maike Rehage, PhD, Christian Weiser, Frederic B. Thalheimer, Hanibal Bohnenberger, Timm Schroeder, PhD, Hubert Serve, MD, Thomas Oellerich, Lothar Hennighausen, Michael A. Rieger, PhD
Journal: Blood
Blood (2014) 124 (21): 4326.
https://doi.org/10.1182/blood.V124.21.4326.4326
Published: 2014
Journal Articles

Altered HSC Metabolism in Response to Stress Leads to De Novo dna Damage and Cellular Attrition

Anja Geiselhart, Dagmar Walter, PhD, Amelie Lier, Frederic B. Thalheimer, Sina Huntscha, David Brocks, Irem Bayindir, Paul Kaschutnig, Katja Müdder, Mirko Sobotta, PhD, Tobias Dick, PhD, Tim Holland-Letz, PhD, Peter Schmezer, PhD, Timm Schröder, PhD, Steven W Lane, MD PhD, Marieke Essers, PhD, Michael A. Rieger, PhD, David A. Williams, MD, Andreas Trumpp, PhD, Michael D. Milsom, PhD
Journal: Blood
Blood (2014) 124 (21): 255.
https://doi.org/10.1182/blood.V124.21.255.255
Published: 2014
Journal Articles

Functional Analysis of the Subclonal Architecture of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) at a Single Cell Level

Bartosch Wojcik, Fabian Lang, MD, Susanne Badura, Anja Vogel, Tamara Tesanovic, Thomas Oellerich, Timm Schroeder, PhD, J.H. Frederik Falkenburg, Monika Brüggemann, Oliver G. Ottmann, MD, Michael A. Rieger, PhD
Journal: Blood
Blood (2014) 124 (21): 3778.
https://doi.org/10.1182/blood.V124.21.3778.3778
Published: 2014