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Journal Articles

Inherited and acquired variations in the hyaluronan synthase 1 ( HAS1 ) gene may contribute to disease progression in multiple myeloma and Waldenstrom macroglobulinemia

Sophia Adamia, Amanda A. Reichert, Hemalatha Kuppusamy, Jitra Kriangkum, Anirban Ghosh, Jennifer J. Hodges, Patrick M. Pilarski, Steven P. Treon, Michael J. Mant, Tony Reiman, Andrew R. Belch, Linda M. Pilarski

Blood (2008) 112 (13): 5111–5121.

https://doi.org/10.1182/blood-2008-02-141770

Published: 2008

Includes: Supplemental data

Journal Articles

Analysis of clonotypic switch junctions reveals multiple myeloma originates from a single class switch event with ongoing mutation in the isotype-switched progeny

Brian J. Taylor, Jitra Kriangkum, Julie A. Pittman, Michael J. Mant, Tony Reiman, Andrew R. Belch, Linda M. Pilarski

Blood (2008) 112 (5): 1894–1903.

https://doi.org/10.1182/blood-2008-01-129221

Published: 2008

Journal Articles

Germline and Somatic Mutations in the Hyaluronan Synthase–1 (HAS1) Gene May Contribute to Oncogenesis in Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Sophia Adamia, PhD, Amanda Reichert, Anirban Ghosh, Ph.D, Jennifer Hodges, Patrick Pilarski, Steven Treon, MD, Michael J. Mant, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, Ph.D

Blood (2007) 110 (11): 2488.

https://doi.org/10.1182/blood.V110.11.2488.2488

Published: 2007

Journal Articles

Accumulation of Inherited and Acquired Mutations in Hyaluronan Synthase1 Gene May Contribute Oncogenesis in Multiple Myeloma and Waldenstrom’s Macroglobulinemia.

Sophia Adamia, Jennifer Hodges, Patrick M. Pilarski, Steven Treon, Michael J. Mant, Tony Reiman, Andrew R. Belch, Linda M. Pilarski

Blood (2006) 108 (11): 3432.

https://doi.org/10.1182/blood.V108.11.3432.3432

Published: 2006

Journal Articles

Molecular Characterization of Clonotypic VDJ Sequences in Waldenstrom’s Macroglobulinemia Suggests Independent Transformation Events in the Development of Biclonal B Cells.

Jitra Kriangkum, PhD, Brian J. Taylor, PhD, Steven P. Treon, MD, PhD, Michael J. Mant, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2006) 108 (11): 4624.

https://doi.org/10.1182/blood.V108.11.4624.4624

Published: 2006

Journal Articles

Impaired class switch recombination (CSR) in Waldenström macroglobulinemia (WM) despite apparently normal CSR machinery

Jitra Kriangkum, Brian J. Taylor, Erin Strachan, Michael J. Mant, Tony Reiman, Andrew R. Belch, Linda M. Pilarski

Blood (2006) 107 (7): 2920–2927.

https://doi.org/10.1182/blood-2005-09-3613

Published: 2006

Journal Articles

Single Nucleotide Polymorphisms (SNPs) and Recurrent Mutations in the Hyaluronan Synthase 1 (HAS1) Gene May Predispose to Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Sophia Adamia, Steve Treon, MD, Daniel Santos, MD, Zachary Hunter, Michael J. Mant, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, Ph.D

Blood (2005) 106 (11): 1558.

https://doi.org/10.1182/blood.V106.11.1558.1558

Published: 2005

Journal Articles

Clonotypic IgG B Cells in Waldenstrom Macroglobulinemia Cells Are Derived from Multiple Post-Transformed B Cells That Have Undergone Isotype Switch Recombination.

Jitra Kriangkum, PhD, Brian J. Taylor, PhD, Erin Strachan, BSc, Tony Reiman, MD, Andrew R. Belch, MD, Michael J. Mant, MD, Linda M. Pilarski, PhD

Blood (2005) 106 (11): 1002.

https://doi.org/10.1182/blood.V106.11.1002.1002

Published: 2005

Journal Articles

Intronic splicing of hyaluronan synthase 1 ( HAS1 ): a biologically relevant indicator of poor outcome in multiple myeloma

Sophia Adamia, Tony Reiman, Mary Crainie, Michael J. Mant, Andrew R. Belch, Linda M. Pilarski

Blood (2005) 105 (12): 4836–4844.

https://doi.org/10.1182/blood-2004-10-3825

Published: 2005

Journal Articles

Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

Jonathan J. Keats, Christopher A. Maxwell, Brian J. Taylor, Michael J. Hendzel, Marta Chesi, P. Leif Bergsagel, Loree M. Larratt, Michael J. Mant, Tony Reiman, Andrew R. Belch, Linda M. Pilarski

Blood (2005) 105 (10): 4060–4069.

https://doi.org/10.1182/blood-2004-09-3704

Published: 2005

Journal Articles

Altered Kinetics and Localization of MMSET Variants Suggests That RE-IIBP Overexpression Is a Unifying Event in t(4;14)(p16;q32) Multiple Myeloma.

Jonathan J. Keats, Christopher A. Maxwell, PhD, Tony Reiman, MD, Brian J. Taylor, PhD, Michael J. Mant, MD, Andrew J. Belch, MD, Linda M. Pilarski, PhD

Blood (2004) 104 (11): 75.

https://doi.org/10.1182/blood.V104.11.75.75

Published: 2004

Journal Articles

Mutator Genes UDG and AID Appear To Be Normal in Class-Switch Deficient and Clonally Homogeneous Waldenstrom’s Macroglobulinemias Having Either Germline or Hypermutated Clonotypic IgH VDJ.

Jitra Kriangkum, PhD, Brian J. Taylor, PhD, Erin R. Strachan, BSc, Steven P. Treon, MD, PhD, Michael J. Mant, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2004) 104 (11): 1359.

https://doi.org/10.1182/blood.V104.11.1359.1359

Published: 2004

Journal Articles

Polymorphisms in the Hyaluronan Synthase 1 Gene May Be Predisposing Factors for Waldenstrom’s Macroglobulinemia.

Sophia Adamia, Steven P. Treon, MD, Michael J. Mant, MD, Loree M. Larratt, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2004) 104 (11): 1363.

https://doi.org/10.1182/blood.V104.11.1363.1363

Published: 2004

Journal Articles

Aberrant Intronic Splicing of the Hyaluronan Synthase 1 Gene (HAS1) in Multiple Myeloma: A Biologically Relevant Marker That Predicts for Poor Survival.

Sophia Adamia, Tony Reiman, MD, Michael J. Mant, MD, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2004) 104 (11): 1413.

https://doi.org/10.1182/blood.V104.11.1413.1413

Published: 2004

Journal Articles

Clonotypic IgM V/D/J sequence analysis in Waldenstrom macroglobulinemia suggests an unusual B-cell origin and an expansion of polyclonal B cells in peripheral blood

Jitra Kriangkum, Brian J. Taylor, Steven P. Treon, Michael J. Mant, Andrew R. Belch, Linda M. Pilarski

Blood (2004) 104 (7): 2134–2142.

https://doi.org/10.1182/blood-2003-11-4024

Published: 2004

Journal Articles

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

Jonathan J. Keats, Tony Reiman, Christopher A. Maxwell, Brian J. Taylor, Loree M. Larratt, Michael J. Mant, Andrew R. Belch, Linda M. Pilarski

Blood (2003) 101 (4): 1520–1529.

https://doi.org/10.1182/blood-2002-06-1675

Published: 2003

Journal Articles

Persistent preswitch clonotypic myeloma cells correlate with decreased survival: evidence for isotype switching within the myeloma clone

Tony Reiman, Karen Seeberger, Brian J. Taylor, Agnieszka J. Szczepek, John Hanson, Michael J. Mant, Robert W. Coupland, Andrew R. Belch, Linda M. Pilarski

Blood (2001) 98 (9): 2791–2799.

https://doi.org/10.1182/blood.V98.9.2791

Published: 2001

Journal Articles

Potential Role for Hyaluronan and the Hyaluronan Receptor RHAMM in Mobilization and Trafficking of Hematopoietic Progenitor Cells

Linda M. Pilarski, Eva Pruski, Juanita Wizniak, Darlene Paine, Karen Seeberger, Michael J. Mant, Christopher B. Brown, Andrew R. Belch

Blood (1999) 93 (9): 2918–2927.

https://doi.org/10.1182/blood.V93.9.2918

Published: 1999

Journal Articles

Overexpression of the Receptor for Hyaluronan-Mediated Motility (RHAMM) Characterizes the Malignant Clone in Multiple Myeloma: Identification of Three Distinct RHAMM Variants

Mary Crainie, Andrew R. Belch, Michael J. Mant, Linda M. Pilarski

Blood (1999) 93 (5): 1684–1696.

https://doi.org/10.1182/blood.V93.5.1684

Published: 1999

Journal Articles

A High Frequency of Circulating B Cells Share Clonotypic Ig Heavy-Chain VDJ Rearrangements With Autologous Bone Marrow Plasma Cells in Multiple Myeloma, as Measured by Single-Cell and In Situ Reverse Transcriptase-Polymerase Chain Reaction

Agnieszka J. Szczepek, Karen Seeberger, Juanita Wizniak, Michael J. Mant, Andrew R. Belch, Linda M. Pilarski

Blood (1998) 92 (8): 2844–2855.

https://doi.org/10.1182/blood.V92.8.2844

Published: 1998

NARROW

Inherited and acquired variations in the hyaluronan synthase 1 ( HAS1 ) gene may contribute to disease progression in multiple myeloma and Waldenstrom macroglobulinemia

Analysis of clonotypic switch junctions reveals multiple myeloma originates from a single class switch event with ongoing mutation in the isotype-switched progeny

Germline and Somatic Mutations in the Hyaluronan Synthase–1 (HAS1) Gene May Contribute to Oncogenesis in Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Accumulation of Inherited and Acquired Mutations in Hyaluronan Synthase1 Gene May Contribute Oncogenesis in Multiple Myeloma and Waldenstrom’s Macroglobulinemia.

Molecular Characterization of Clonotypic VDJ Sequences in Waldenstrom’s Macroglobulinemia Suggests Independent Transformation Events in the Development of Biclonal B Cells.

Impaired class switch recombination (CSR) in Waldenström macroglobulinemia (WM) despite apparently normal CSR machinery

Single Nucleotide Polymorphisms (SNPs) and Recurrent Mutations in the Hyaluronan Synthase 1 (HAS1) Gene May Predispose to Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Clonotypic IgG B Cells in Waldenstrom Macroglobulinemia Cells Are Derived from Multiple Post-Transformed B Cells That Have Undergone Isotype Switch Recombination.

Intronic splicing of hyaluronan synthase 1 ( HAS1 ): a biologically relevant indicator of poor outcome in multiple myeloma

Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

Altered Kinetics and Localization of MMSET Variants Suggests That RE-IIBP Overexpression Is a Unifying Event in t(4;14)(p16;q32) Multiple Myeloma.

Mutator Genes UDG and AID Appear To Be Normal in Class-Switch Deficient and Clonally Homogeneous Waldenstrom’s Macroglobulinemias Having Either Germline or Hypermutated Clonotypic IgH VDJ.

Polymorphisms in the Hyaluronan Synthase 1 Gene May Be Predisposing Factors for Waldenstrom’s Macroglobulinemia.

Aberrant Intronic Splicing of the Hyaluronan Synthase 1 Gene (HAS1) in Multiple Myeloma: A Biologically Relevant Marker That Predicts for Poor Survival.

Clonotypic IgM V/D/J sequence analysis in Waldenstrom macroglobulinemia suggests an unusual B-cell origin and an expansion of polyclonal B cells in peripheral blood

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

Persistent preswitch clonotypic myeloma cells correlate with decreased survival: evidence for isotype switching within the myeloma clone

Potential Role for Hyaluronan and the Hyaluronan Receptor RHAMM in Mobilization and Trafficking of Hematopoietic Progenitor Cells

Overexpression of the Receptor for Hyaluronan-Mediated Motility (RHAMM) Characterizes the Malignant Clone in Multiple Myeloma: Identification of Three Distinct RHAMM Variants

A High Frequency of Circulating B Cells Share Clonotypic Ig Heavy-Chain VDJ Rearrangements With Autologous Bone Marrow Plasma Cells in Multiple Myeloma, as Measured by Single-Cell and In Situ Reverse Transcriptase-Polymerase Chain Reaction

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American Society of Hematology

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ASH Publications

American Society of Hematology

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