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Journal Articles

Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity

Alejandra Ortiz-Ruiz, BSc, Yanira Ruiz-Heredia, Mehmet Samur, PhD, Pedro Aguilar-Garrido, Maria Luz Morales, Antonio Valeri, PhD, Almudena Garcia-Ortiz, PhD, Santiago Barrio, PhD, Carmen Bárcena, Rosa Maria Garcia-Martin, Vanesa Garrido, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD, María Teresa Cedena, Joaquin Martinez-Lopez, MD PhD, Maria Linares, PhD, Miguel Gallardo, PhD

Blood (2019) 134 (Supplement_1): 4408.

https://doi.org/10.1182/blood-2019-123950

Published: 2019

Journal Articles

Clonal Competition Models to Understand Progression and Resistance in Myeloma

Santiago Barrio, PhD, Larissa Haertle, PhD, Umair Munawar, MSc, Lucia Martin, Isabel Cuenca, MSc, Cornelia Vogt, MSc, Andoni Garitano-Trojaola, PhD, Matteo Claudio Da Via', MD, Miguel Gallardo, PhD, Thorsten Stuehmer, PhD, Hermann Einsele, MD, Leo Rasche, MD, Joaquin Martinez-Lopez, MD PhD, Martin Kortüm, MD

Blood (2019) 134 (Supplement_1): 1807.

https://doi.org/10.1182/blood-2019-130812

Published: 2019

Journal Articles

Combination Therapy with BTK Inhibitor Plus Anti-PD-1 Antibody Results in a Hyperprogressor Phenotype in a Mouse Model of CLL

Aidi Gu, PhD, Huaxian Ma, MS, Xiaorui Zhang, BS, Prerna Malaney, PhD, Miguel Gallardo, PhD, Jingwei Liu, MD, Sattva S. Neelapu, MD, Sean M Post, PhD

Blood (2018) 132 (Supplement 1): 4416.

https://doi.org/10.1182/blood-2018-99-118773

Published: 2018

Journal Articles

hnRNP K Overexpression Drives Myeloid Malignancy Via Interaction with RUNX1

Marisa J Hornbaker, BS, Prerna Malaney, PhD, Xiaorui Zhang, BS, Ruizhi Duan, M.Sc., Vrutant Shah, PhD, Shelley Herbrich, MS, Miguel Gallardo, PhD, Rodrigo Jacamo, PhD, Todd Link, PhD, Huaxian Ma, MS, Sanzhar Alybayev, MS, Steven M. Kornblau, MD, Peter Hu, PhD, Dos Sarbassov, PhD, Rashmi Kanagal-Shamanna, MD, Carlos E. Bueso-Ramos, MD PhD, Sean M Post, PhD

Blood (2018) 132 (Supplement 1): 2622.

https://doi.org/10.1182/blood-2018-99-117387

Published: 2018

Journal Articles

hnRNP K: A Regulator of Global Transcription and Translation That Drives Lymphomagenesis

Blood (2018) 132 (Supplement 1): 1346.

https://doi.org/10.1182/blood-2018-99-116163

Published: 2018

Journal Articles

Abnormalities in Mitochondrial DNA Copy Number Have Pathogenetic and Prognostic Implications in Multiple Myeloma

Blood (2017) 130 (Supplement 1): 4378.

https://doi.org/10.1182/blood.V130.Suppl_1.4378.4378

Published: 2017

Journal Articles

Role of MAX As a Tumor Suppressor Driver Gene in Multiple Myeloma

Santiago Barrio Garcia, PhD, Yanira Ruiz-Heredia, Matteo Da Via', MD, Miguel Gallardo, PhD, Andoni Garitano-Trojaola, PhD, Josip Zovko, MD, Marc S Raab, MD PhD, Pieter Sonneveld, MDPhD, Esteban Braggio, PhD, A. Keith Stewart, MBChB, MBA, Hermann Einsele, Joaquín Martínez, K. Martin Kortüm, MD

Blood (2017) 130 (Supplement 1): 4347.

https://doi.org/10.1182/blood.V130.Suppl_1.4347.4347

Published: 2017

Journal Articles

hnRNP K: A Driver of Myeloid Malignancy

Marisa J Hornbaker, BS, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Prerna Malaney, PhD, Shelley Herbrich, MS, Huaxian Ma, Peter Hu, PhD, Steven Kornblau, MD, Carlos E. Bueso-Ramos, MD PhD, Sean M Post, PhD

Blood (2017) 130 (Supplement 1): 2511.

https://doi.org/10.1182/blood.V130.Suppl_1.2511.2511

Published: 2017

Journal Articles

AXL Inhibitor ONO-9330547 Suppresses PLK1 Gene and Protein Expression and Effectively Induces Growth Arrest and Apoptosis in FLT3 ITD Acute Myeloid Leukemia Cells

Peter Ruvolo, PhD, Huaxian Ma, BS, Vivian Ruvolo, MS, Hong Mu, MD PhD, Wendy Schober, Tomoko Yasuhiro, Toshio Yoshizawa, PhD, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Joseph D Khoury, MD, Jorge Cortes, MD, Michael Andreeff, MD PhD, Sean M. Post, PhD

Blood (2016) 128 (22): 3939.

https://doi.org/10.1182/blood.V128.22.3939.3939

Published: 2016

Journal Articles

hnRNP K Overexpression Drives AML Progression By Altering Pathways Critical for Myeloid Proliferation and Differentiation

Marisa J Hornbaker, BS, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Huaxian Ma, BS, Peter Hu, PhD, Joseph D Khoury, MD, Steven M. Kornblau, MD, Carlos E Bueso-Ramos, MD PhD, Sean M. Post, PhD

Blood (2016) 128 (22): 744.

https://doi.org/10.1182/blood.V128.22.744.744

Published: 2016

Journal Articles

Developing Therapeutic Strategies for CLL with Mutant p53

Hun Ju Lee, MD, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Huaxian Ma, BS, Alfonso Quintas-Cardama, MD, Yuan Qi, Xiaoping Su, PhD, Sean M. Post, PhD

Blood (2015) 126 (23): 2476.

https://doi.org/10.1182/blood.V126.23.2476.2476

Published: 2015

Journal Articles

Amplification of hnRNP K Drives c-Myc-Dependent Malignancies and Represent a Novel Therapeutic Opportunity for Hematologic Malignancies

Miguel Gallardo, PhD, Xiaorui Zhang, BS, Mark McArthur, Taghi Manshouri, PhD, Sean M. Post, PhD

Blood (2015) 126 (23): 468.

https://doi.org/10.1182/blood.V126.23.468.468

Published: 2015

Journal Articles

hnRNP K Is a Novel Haploinsufficient Tumor Suppressor at the 9q21.32 Locus That Defines a Subset of AML

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, BS, Carlos E. Bueso-Ramos, MD, Laura Pageon, Mark McArthur, Asha Multani, Aziz Nazha, MD, Taghi Manshouri, PhD, Jan Parker-Thornburg, Peter Hu, Yuan Qi, Xiaoping Su, PhD, Inmaculada Rapado, Alfonso Quintás-Cardama, Steven M. Kornblau, MD, Joaquin Martinez-López, MDPhD, Sean M. Post, PhD

Blood (2015) 126 (23): 439.

https://doi.org/10.1182/blood.V126.23.439.439

Published: 2015

Journal Articles

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Markus Reschke, PhD, John G Clohessy, Alfonso Quintás-Cardama, MD, Michael Andreeff, MD PhD, Steven M. Kornblau, MD, Pier Paolo Pandolfi, MD PhD, Sean M. Post, PhD

Blood (2014) 124 (21): 2382.

https://doi.org/10.1182/blood.V124.21.2382.2382

Published: 2014

Journal Articles

hnRNP K : A Tumor Suppressor or Oncogene?

Miguel Gallardo, PhD, Hun Ju Lee, MD, Carlos E. Bueso-Ramos, MD PhD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Inmaculada Rapado, Alfonso Quintás-Cardama, MD, Steven M. Kornblau, MD, Joaquin Martinez-Lopez, Sean M. Post, PhD

Blood (2014) 124 (21): 259.

https://doi.org/10.1182/blood.V124.21.259.259

Published: 2014

Journal Articles

p53 Pathway Alterations Influence Survival and Treatment Response In Chronic Lymphocytic Leukemia

Hun Ju Lee, MD, Miguel Gallardo, PhD, Xiaorui Zhang, Alfonso Quintas-Cardama, Sean M. Post, PhD

Blood (2013) 122 (21): 2885.

https://doi.org/10.1182/blood.V122.21.2885.2885

Published: 2013

Journal Articles

BET Bromodomain Inhibition Reduces Leukemic Burden and Prolongs Survival In The Eμ-TCL1 Transgenic Mouse Model Of Chronic Lymphocytic Leukemia (CLL) Independent Of TP53 Mutation Status

Connie A Larsson, Kensuke Kojima, MD, PhD, Yong Wang, PhD, Nicholas Navin, PhD, Miguel Gallardo, PhD, Daniel Primo, Jose L. Rojas, Joaquin Martinez, Taghi Manshouri, Ph.D., Hun Ju Lee, MD, James E Bradner, MD, Juan Ballesteros, Sean M. Post, PhD, Guillermina (Gigi) Lozano, PhD, Alfonso Quintás-Cardama, MD

Blood (2013) 122 (21): 876.

https://doi.org/10.1182/blood.V122.21.876.876

Published: 2013

Journal Articles

hnRNP K: A Novel Regulator of Hematopoiesis and A Potential Predictive Biomarker In Acute Myeloid Leukemia

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, Aziz Nazha, MD, Laura R. Pageon, Steven M. Kornblau, MD, Alfonso Quintás-Cardama, MD, Sean M. Post, PhD

Blood (2013) 122 (21): 226.

https://doi.org/10.1182/blood.V122.21.226.226

Published: 2013

NARROW

Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity

Clonal Competition Models to Understand Progression and Resistance in Myeloma

Combination Therapy with BTK Inhibitor Plus Anti-PD-1 Antibody Results in a Hyperprogressor Phenotype in a Mouse Model of CLL

hnRNP K Overexpression Drives Myeloid Malignancy Via Interaction with RUNX1

hnRNP K: A Regulator of Global Transcription and Translation That Drives Lymphomagenesis

Abnormalities in Mitochondrial DNA Copy Number Have Pathogenetic and Prognostic Implications in Multiple Myeloma

Role of MAX As a Tumor Suppressor Driver Gene in Multiple Myeloma

hnRNP K: A Driver of Myeloid Malignancy

AXL Inhibitor ONO-9330547 Suppresses PLK1 Gene and Protein Expression and Effectively Induces Growth Arrest and Apoptosis in FLT3 ITD Acute Myeloid Leukemia Cells

hnRNP K Overexpression Drives AML Progression By Altering Pathways Critical for Myeloid Proliferation and Differentiation

Developing Therapeutic Strategies for CLL with Mutant p53

Amplification of hnRNP K Drives c-Myc-Dependent Malignancies and Represent a Novel Therapeutic Opportunity for Hematologic Malignancies

hnRNP K Is a Novel Haploinsufficient Tumor Suppressor at the 9q21.32 Locus That Defines a Subset of AML

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

hnRNP K : A Tumor Suppressor or Oncogene?

p53 Pathway Alterations Influence Survival and Treatment Response In Chronic Lymphocytic Leukemia

BET Bromodomain Inhibition Reduces Leukemic Burden and Prolongs Survival In The Eμ-TCL1 Transgenic Mouse Model Of Chronic Lymphocytic Leukemia (CLL) Independent Of TP53 Mutation Status

hnRNP K: A Novel Regulator of Hematopoiesis and A Potential Predictive Biomarker In Acute Myeloid Leukemia

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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