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Journal Articles

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Virginia A Turati, PhD, José Afonso Guerra-Assunção, PhD, John C Ambrose, PhD, John Brown, PhD, Mike Hubank, PhD, Alex Hobbs, PhD, Mark Lynch, PhD, Bernadett Gaal, PhD, Sarah Inglott, Lucia Conde, PhD, Simon Richardson, MD PhD, Javier Herrero, PhD, Sten Eirik Jacobsen, MD PhD, Tariq Enver, PhD

Blood (2016) 128 (22): 606.

https://doi.org/10.1182/blood.V128.22.606.606

Published: 2016

Journal Articles

Immunoglobulin/T-Cell Receptor (Ig/TCR) Allele Usage in Normal and on Treatment Bone Marrow Samples in Childhood Acute Lymphoblastic Leukaemia - Implications for NGS Based MRD Analysis

John Moppett, MD PhD, Stephanie Wakeman, BSc, Marc Duez, Jack Bartram, MD, Gary Wright, Mike Hubank, PhD, Helen Williamson, Paul Archer, Jerry Hancock, PhD

Blood (2016) 128 (22): 4073.

https://doi.org/10.1182/blood.V128.22.4073.4073

Published: 2016

Journal Articles

Artificial DNA Templates for the Correction of PCR Bias in Next Generation Sequencing Based MRD Analysis for Childhood Acute Lymphoblastic Leukaemia: The Influence of Secondary DNA Structure

John Moppett, MD PhD, Jerry Hancock, PhD, Marc Duez, Jack Bartram, MD, Gary Wright, Mike Hubank, PhD, Paul Archer, Helen Williamson, Stephanie Wakeman, BSc

Blood (2016) 128 (22): 4078.

https://doi.org/10.1182/blood.V128.22.4078.4078

Published: 2016

Journal Articles

The Role of SMAD7 Downstream of TEL-AML1 Signalling in t(12;21) Acute Lymphoblastic Leukemia

Aishwarya Sundaresh, Miss, Maurizio Mangolini, Dr, Jasper de Boer, Dr, Mike Hubank, Dr, Nicholas Goulden, Dr, Owen Williams, PhD

Blood (2015) 126 (23): 4823.

https://doi.org/10.1182/blood.V126.23.4823.4823

Published: 2015

Journal Articles

Development Of Minimal Residual Disease (MRD) Analysis In Childhood Acute Lymphoblastic Leukaemia (ALL) By Next Generation Sequencing (NGS)

Helen Williamson, Edward Mountjoy, Hashem Shihab, Jack Bartram, Mike Hubank, Nicholas Goulden, Ian Day, Eileen Roberts, John Moppett, Jeremy Hancock

Blood (2013) 122 (21): 2569.

https://doi.org/10.1182/blood.V122.21.2569.2569

Published: 2013

Journal Articles

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival

Azra J. Alvi, Belinda Austen, Victoria J. Weston, Christopher Fegan, David MacCallum, Athos Gianella-Borradori, David P. Lane, Mike Hubank, Judith E. Powell, Wenbin Wei, A. Malcolm R. Taylor, Paul A. H. Moss, Tatjana Stankovic

Blood (2005) 105 (11): 4484–4491.

https://doi.org/10.1182/blood-2004-07-2713

Published: 2005

Journal Articles

Microarray analysis reveals that TP53 - and ATM -mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

Tatjana Stankovic, Mike Hubank, Debbie Cronin, Grant S. Stewart, Danielle Fletcher, Colin R. Bignell, Azra J. Alvi, Belinda Austen, Victoria J. Weston, Christopher Fegan, Philip J. Byrd, Paul A. H. Moss, A. Malcolm R. Taylor

Blood (2004) 103 (1): 291–300.

https://doi.org/10.1182/blood-2003-04-1161

Published: 2004

NARROW

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Immunoglobulin/T-Cell Receptor (Ig/TCR) Allele Usage in Normal and on Treatment Bone Marrow Samples in Childhood Acute Lymphoblastic Leukaemia - Implications for NGS Based MRD Analysis

Artificial DNA Templates for the Correction of PCR Bias in Next Generation Sequencing Based MRD Analysis for Childhood Acute Lymphoblastic Leukaemia: The Influence of Secondary DNA Structure

The Role of SMAD7 Downstream of TEL-AML1 Signalling in t(12;21) Acute Lymphoblastic Leukemia

Development Of Minimal Residual Disease (MRD) Analysis In Childhood Acute Lymphoblastic Leukaemia (ALL) By Next Generation Sequencing (NGS)

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival

Microarray analysis reveals that TP53 - and ATM -mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

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ASH Publications

American Society of Hematology

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Immunoglobulin/T-Cell Receptor (Ig/TCR) Allele Usage in Normal and on Treatment Bone Marrow Samples in Childhood Acute Lymphoblastic Leukaemia - Implications for NGS Based MRD Analysis

Artificial DNA Templates for the Correction of PCR Bias in Next Generation Sequencing Based MRD Analysis for Childhood Acute Lymphoblastic Leukaemia: The Influence of Secondary DNA Structure

The Role of SMAD7 Downstream of TEL-AML1 Signalling in t(12;21) Acute Lymphoblastic Leukemia

Development Of Minimal Residual Disease (MRD) Analysis In Childhood Acute Lymphoblastic Leukaemia (ALL) By Next Generation Sequencing (NGS)

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival

Microarray analysis reveals that TP53 - and ATM -mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

Email alerts

ASH Publications

American Society of Hematology

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