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Mileidys Perez
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Journal Articles

Odyssey: A first-in-human study of the aldehyde dehydrogenase (ALDH) inhibitor abd-3001 in patients with refractory/relapsed acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS)

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Mael Heiblig, Lina Benajiba, Julien Colle, Sandrine Loron, Juliette Soret, Rafael Daltro De Oliveira, Geoffroy Venton, Marie-Virginie Larcher, Laure Farnault, Mühübe Yazir, Mileidys Perez, Ismail Ceylan, Guillaume Martin, Annick Pelletier, Jean-Jacques Kiladjian, Régis Costello
Journal: Blood
Blood (2025) 146 (Supplement 1): 3421.
https://doi.org/10.1182/blood-2025-3421
Published: 2025
Journal Articles

Anthracyclines induce epigenetic changes in ALDH1A that promote chemoresistance in AML, revealing a potential treatment strategy co-targeting ALDH1A inhibition with hypomethylating agents

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Mehak Shaikh, Francesco Leonetti, Mühübe Yazir, Celine Baier, Miroslava Adamcova, Andrada Constantineascu, Iris Manosalva, Regis Costello, Guillaume Martin, Salvatore Spicuglia, Meritxell Alberich-Jorda, Mileidys Perez
Journal: Blood
Blood (2025) 146 (Supplement 1): 214.
https://doi.org/10.1182/blood-2025-214
Published: 2025
Journal Articles

Odyssey: A First-in-Human Study of the Aldehyde Dehydrogenase (ALDH) Inhibitor Abd-3001 in Patients with Refractory/Relapsed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

Free
Lina Benajiba, Julien Colle, Mael Heiblig, Sandrine Loron, Juliette Soret-Dulphy, Paul Berchard, Mühübe Yazir, Laurent Basset, Geoffroy Venton, Marie-Virginie Larcher, Rafael Daltro De Oliveira, Gaëlle Fossard, Guillaume Martin, Mileidys Perez, Ismael Ceylan, Annick Pelletier, Jean-Jacques Kiladjian, Régis Costello
Journal: Blood
Blood (2024) 144 (Supplement 1): 6001.
https://doi.org/10.1182/blood-2024-204998
Published: 2024
Journal Articles

Dual Targeting of ALDH1 and ALDH3: A Promising Therapeutic Approach in Acute Myeloid Leukemia

Free
Mileidys Perez-Alea, Sr., PhD, Julien Colle, Jr., MD, Muhube Yazir, Jr., MSc, Céline Baier, Jr., PhD, Yasmine Labiad, PhD, Isabelle Arnoux, Sr., Hematologist, Geoffroy Venton, Jr., PhD MD, Guillaume Guillaume, MSc, Ismail Ceylan, MSc, Regis T. Costello, Sr., MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3364.
https://doi.org/10.1182/blood-2019-126484
Published: 2019