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Journal Articles

Memory T-Cell Add Back and Prophylactic blinatumomab Post Tcrαβ Depleted Haploidentical Transplantation Results in Promising Outcomes in Pediatric Patients with High-Risk Acute Leukemia

Blood (2024) 144 (Supplement 1): 383.

https://doi.org/10.1182/blood-2024-208547

Published: 2024

Journal Articles

CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia

Blood (2024) 144 (Supplement 1): 2076.

https://doi.org/10.1182/blood-2024-208795

Published: 2024

Journal Articles

Safety and Anti-Leukemic Activity of CD123-CAR T Cells in Pediatric Patients with AML: Preliminary Results from a Phase 1 Trial

Blood (2022) 140 (Supplement 1): 4584–4585.

https://doi.org/10.1182/blood-2022-170201

Published: 2022

Journal Articles

Establishing Immunocompetent Leukemia Models to Investigate the Impact of CAR T Cells on the Immune Microenvironment and Bone Marrow Niche

Sarah E. Moore, Jaquelyn T. Zoine, Jeremy Chase Crawford, Deanna Langfitt, Juan M. Barajas, Sherif Abdelhamed, Ilaria Iacobucci, Dalia Haydar, Giedre Krenciute, Charles G. Mullighan, Jeffery M. Klco, Stephen Gottschalk, Paul G. Thomas, Mireya Paulina Velasquez

Blood (2022) 140 (Supplement 1): 7376–7377.

https://doi.org/10.1182/blood-2022-169800

Published: 2022

Journal Articles

LigandCD70.CAR As a Platform for Dual-Targeting CAR T Cells for Acute Myeloid Leukemia

Lauren Scherer, Candise Tat, Tim Sauer, Haruko Tashiro, Swati Naik, Mireya Paulina Velasquez, Stephen Gottschalk, Cliona M. Rooney, Malcolm K. Brenner, Bilal Omer

Blood (2022) 140 (Supplement 1): 7396–7397.

https://doi.org/10.1182/blood-2022-170503

Published: 2022

Journal Articles

Structural Changes in Peptide-Scfv Bispecific Cars Impact T Cell Effector Function Against Acute Myeloid Leukemia

Jaquelyn T. Zoine, Sarah E. Moore, Kalyan Immadisetty, Shams Akel, Deanna M Langfitt, Jorge Ibanez-Vega, Lindsay Talbot, Chris DeRenzo, Giedre Krenciute, M. Madan Babu, Mireya Paulina Velasquez

Blood (2022) 140 (Supplement 1): 4506–4507.

https://doi.org/10.1182/blood-2022-169508

Published: 2022

Journal Articles

CD45RA-Depleted Haploidentical Transplantation Combined with NK Cell Addback Results in Promising Long-Term Outcomes in Pediatric Patients with High-Risk Hematologic Malignancies

Swati Naik, Aimee C Talleur, Ying Li, Renee M. Madden, Ewelina Mamcarz, Amr Qudeimat, Akshay Sharma, Ashok Srinivasan, Ali Y Suliman, Rebecca Epperly, Esther A. Obeng, Mireya Paulina Velasquez, Diego Hijano, Gabriela Maron, Stephen Gottschalk, Brandon M Triplett

Blood (2021) 138 (Supplement 1): 172.

https://doi.org/10.1182/blood-2021-149655

Published: 2021

Journal Articles

CD45RO+ T-Cell Add Back and Prophylactic Blinatumomab Administration Post Tcrαβ/CD19-Depleted Haploidentical Transplantation in Pediatric Patients with High Risk Acute Leukemia

Swati Naik, Renee M. Madden, Ewelina Mamcarz, Ashok Srinivasan, Akshay Sharma, Aimee C Talleur, Rebecca Epperly, Amr Qudeimat, Ali Y Suliman, Esther A. Obeng, Mireya Paulina Velasquez, Diego Hijano, Gabriela Maron, Ying Li, Stephen Gottschalk, Brandon M Triplett

Blood (2021) 138 (Supplement 1): 2897.

https://doi.org/10.1182/blood-2021-149671

Published: 2021

Journal Articles

Allogeneic Hematopoietic Cell Transplantation Is Critical to Maintain Remissions after CD19-CAR T-Cell Therapy for Pediatric ALL: A Single Center Experience

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-138528

Published: 2020

Journal Articles

GRP78 Is Expressed on the Cell Surface of Pediatric AML Blasts and Can be Targeted with GRP78-CAR T Cells without Toxicity to Hematopoietic Progenitor Cells

Nikhil Hebbar, PhD, Rebecca Epperly, MD, Abishek Vaidya, MS, Sujuan Huang, Cheng Cheng, PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD

Blood (2020) 136 (Supplement 1): 12.

https://doi.org/10.1182/blood-2020-141671

Published: 2020

Journal Articles

Venetoclax Enhances Anti-Leukemia Activity of CD123-Specific BiTE-Secreting T-Cells in AML

Hong Mu-Mosley, MDPhD, Lauren B Ostermann, BS, Ran Zhao, BS, Challice L. Bonifant, MDPhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD, Michael Andreeff, MD PhD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-139625

Published: 2020

Journal Articles

Multi-Omic Based Antigen Discovery for the Immunotherapy of Pediatric Acute T Cell Lymphoblastic Leukemia

Nikhil Hebbar, PhD, Chunxu Qu, PhD, Hong Wang, PhD, Ying Shao, Phuong Nguyen, Abdullah Freiwan, MSc, Rebecca Epperly, MD, Yuxin Li, Ji-Hoon Cho, Timothy Shaw, PhD, Junmin Peng, PhD, John Easton, PhD, Stephen Gottschalk, MD, Charles G Mullighan, MBBS, MD, Mireya Paulina Velasquez, MD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-141707

Published: 2020

Journal Articles

Engineering Naturally Occurring CD7 Negative Cells for the Immunotherapy of CD7 Positive Leukemia

Abdullah Freiwan, MSc, Abishek Vaidya, MS, Caitlin Zebley, MD, Yiping Fan, PhD, Deanna Langfitt, PhD, Benjamin Youngblood, PhD, Maksim Mamonkin, PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD

Blood (2019) 134 (Supplement_1): 868.

https://doi.org/10.1182/blood-2019-124903

Published: 2019

Journal Articles

Inducible MyD88 Signaling Enhances the Anti-AML Activity of BiTE-Secreting ENG T-Cells

Abishek Vaidya, MS, Erin E Doherty, MD, Xiya Wu, Challice L. Bonifant, MD PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD

Blood (2019) 134 (Supplement_1): 4441.

https://doi.org/10.1182/blood-2019-125395

Published: 2019

Journal Articles

Transgenic Expression of IL15 in CD123-Specific BiTE-Secreting Engager T-Cells Results in Improved Anti-AML Activity

Hong Mu-Mosley, MD PhD, Lauren B Ostermann, Muharrem Muftuoglu, MD, Wendy Schober, Nalini B Patel, Abishek Vaidya, MS, Challice L. Bonifant, MD PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 3917.

https://doi.org/10.1182/blood-2019-125928

Published: 2019

Journal Articles

Redirecting T cells to hematological malignancies with bispecific antibodies

Mireya Paulina Velasquez, Challice L. Bonifant, Stephen Gottschalk

Blood (2018) 131 (1): 30–38.

https://doi.org/10.1182/blood-2017-06-741058

Published: 2018

Journal Articles

Targeting CD19: the good, the bad, and CD81

Mireya Paulina Velasquez, Stephen Gottschalk

Blood (2017) 129 (1): 9–10.

https://doi.org/10.1182/blood-2016-11-749143

Published: 2017

Journal Articles

Fast and Efficient Gene Editing in Human Hematopoietic Cells

Michael C Gundry, BS, Lorenzo Brunetti, MD, Dimitrios Laurin Wagner, Joanne Hsu, BS, Mireya Paulina Velasquez, MD, Stephen Gottschalk, MD, Cliona M. Rooney, PhD, Margaret Goodell, PhD

Blood (2016) 128 (22): 4704.

https://doi.org/10.1182/blood.V128.22.4704.4704

Published: 2016

Journal Articles

Two-Pronged Cell Therapy for B-Cell Malignancies: Engineering NK Cells to Target CD22 and Redirect Bystander T Cells to CD19

Mireya Paulina Velasquez, MD, Arpad Szoor, MD PhD, Challice L. Bonifant, MD PhD, Abishek Vaidya, Lorenzo Brunetti, MD, Michael C Gundry, BS, Robin Parihar, MD PhD, Margaret Goodell, PhD, Stephen Gottschalk, MD

Blood (2016) 128 (22): 4560.

https://doi.org/10.1182/blood.V128.22.4560.4560

Published: 2016

Journal Articles

CD123-Engager T Cells As a Novel Immunotherapeutic for AML

Challice L. Bonifant, MD PhD, David Torres, Mireya Paulina Velasquez, MD, Kota Iwahori, MD, Caroline Arber, MD, Xiao-Tong Song, PhD, Michele S. Redell, MD PhD, Stephen Gottschalk, MD

Blood (2014) 124 (21): 3762.

https://doi.org/10.1182/blood.V124.21.3762.3762

Published: 2014

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Memory T-Cell Add Back and Prophylactic blinatumomab Post Tcrαβ Depleted Haploidentical Transplantation Results in Promising Outcomes in Pediatric Patients with High-Risk Acute Leukemia

CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia

Safety and Anti-Leukemic Activity of CD123-CAR T Cells in Pediatric Patients with AML: Preliminary Results from a Phase 1 Trial

Establishing Immunocompetent Leukemia Models to Investigate the Impact of CAR T Cells on the Immune Microenvironment and Bone Marrow Niche

LigandCD70.CAR As a Platform for Dual-Targeting CAR T Cells for Acute Myeloid Leukemia

Structural Changes in Peptide-Scfv Bispecific Cars Impact T Cell Effector Function Against Acute Myeloid Leukemia

CD45RA-Depleted Haploidentical Transplantation Combined with NK Cell Addback Results in Promising Long-Term Outcomes in Pediatric Patients with High-Risk Hematologic Malignancies

CD45RO+ T-Cell Add Back and Prophylactic Blinatumomab Administration Post Tcrαβ/CD19-Depleted Haploidentical Transplantation in Pediatric Patients with High Risk Acute Leukemia

Allogeneic Hematopoietic Cell Transplantation Is Critical to Maintain Remissions after CD19-CAR T-Cell Therapy for Pediatric ALL: A Single Center Experience

GRP78 Is Expressed on the Cell Surface of Pediatric AML Blasts and Can be Targeted with GRP78-CAR T Cells without Toxicity to Hematopoietic Progenitor Cells

Venetoclax Enhances Anti-Leukemia Activity of CD123-Specific BiTE-Secreting T-Cells in AML

Multi-Omic Based Antigen Discovery for the Immunotherapy of Pediatric Acute T Cell Lymphoblastic Leukemia

Engineering Naturally Occurring CD7 Negative Cells for the Immunotherapy of CD7 Positive Leukemia

Inducible MyD88 Signaling Enhances the Anti-AML Activity of BiTE-Secreting ENG T-Cells

Transgenic Expression of IL15 in CD123-Specific BiTE-Secreting Engager T-Cells Results in Improved Anti-AML Activity

Redirecting T cells to hematological malignancies with bispecific antibodies

Targeting CD19: the good, the bad, and CD81

Fast and Efficient Gene Editing in Human Hematopoietic Cells

Two-Pronged Cell Therapy for B-Cell Malignancies: Engineering NK Cells to Target CD22 and Redirect Bystander T Cells to CD19

CD123-Engager T Cells As a Novel Immunotherapeutic for AML

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