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Monica Schenone
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Journal Articles

CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1

Roger Belizaire, Sebastian H. J. Koochaki, Namrata D. Udeshi, Alexis Vedder, Lei Sun, Tanya Svinkina, Christina Hartigan, Marie McConkey, Veronica Kovalcik, Amanuel Bizuayehu, Caroline Stanclift, Monica Schenone, Steven A. Carr, Eric Padron, Benjamin L. Ebert
Journal: Blood
Blood (2021) 137 (16): 2209–2220.
https://doi.org/10.1182/blood.2020006528
Published: 2021
Includes: Supplemental data
Journal Articles

Oncogenic Mechanisms of CBL E3 Ubiquitin Ligase Mutations in Myeloid Malignancies

Roger Belizaire, MD PhD, Sebastian Koochaki, BS, MS, Namrata Udeshi, PhD, Alexis Vedder, BS, Lei Sun, Monica Schenone, PhD, Steven Carr, PhD, Eric Padron, MD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 563.
https://doi.org/10.1182/blood-2019-122503
Published: 2019
Journal Articles

Dual Effects of BCOR-PRC1.1 Dependent Gene Regulation Mediate Cooperation of BCOR and TET2 Mutations in Myeloid Transformation

Eva Johanna Schaefer, MD, Iman Fares, PhD, Clifford Meyer, PhD, Paloma Cejas, PhD, Annie Apffel, BA, Monica Schenone, PhD, Henry W Long, PhD, R. Coleman Lindsley, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 651.
https://doi.org/10.1182/blood-2018-99-119519
Published: 2018
Journal Articles

Control of Human Hemoglobin Switching By LIN28B-Mediated Regulation of BCL11A Translation

Anindita Basak, PhD, Mathias Munschauer, PhD, Jacob C. Ulirsch, BS, Kara E. Montbleau, Christina R. Hartigan, BS, Monica Schenone, PhD, John Lian, PhD, Yaomei Wang, Yumin Huang, Xianfang Wu, Lee Gehrke, Charles M. Rice, Xiuli An, MD PhD, Helen A. Christou, Mohandas Narla, DSc, Steven A. Carr, PhD, Stuart H. Orkin, MD, Jane-Jane Chen, PhD, Eric S. Lander, Vijay G. Sankaran, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 412.
https://doi.org/10.1182/blood-2018-99-117440
Published: 2018
Journal Articles

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

Zuzana Tothova, MD PhD, John M. Krill-Burger, MS, Daniel S. Day, PhD, J. Erika Haydu, MD PhD, Brian J. Abraham, PhD, Catherine C. Landers, BA, Edyta Malolepsza, PhD, Christina R. Hartigan, BS, Amie Holmes, PhD, Melanie Donahue, BS, Katerina D. Popova, BA, Sebastian Koochaki, MS, Jeanne Rivera, BSc, Michael Seiler, PhD, Denes Hnisz, PhD, Edwin Chen, PhD, Silvia Buonamici, PhD, Monica Schenone, PhD, Alan D. D'Andrea, MD, Steven A. Carr, PhD, Richard A. Young, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 940.
https://doi.org/10.1182/blood-2018-99-117480
Published: 2018
Journal Articles

Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma

Mariateresa Fulciniti, Joaquin Martinez-Lopez, William Senapedis, Stefania Oliva, Rajya Lakshmi Bandi, Nicola Amodio, Yan Xu, Raphael Szalat, Annamaria Gulla, Mehmet K. Samur, Aldo Roccaro, Maria Linares, Michele Cea, Erkan Baloglu, Christian Argueta, Yosef Landesman, Sharon Shacham, Siyuan Liu, Monica Schenone, Shiaw-Lin Wu, Barry Karger, Rao Prabhala, Kenneth C. Anderson, Nikhil C. Munshi
Journal: Blood
Blood (2017) 129 (16): 2233–2245.
https://doi.org/10.1182/blood-2016-06-724831
Published: 2017
Includes: Supplemental data
Journal Articles

Cooperating Effect of Rps14 , Csnk1a1 and miRNA145/miRNA146a Haploinsufficiency in the Activation of the Innate Immune System in Del(5q) MDS

Schneider K. Rebekka, MD, Monica Schenone, PhD, Monica Ferreira Ventura, PhD, Fabian Beier, MD, Tim H. Bruemmendorf, MD, Ulrich Germing, MD, Uwe Platzbecker, MD, Guntram Büsche, MD, Marie E. McConkey, PhD, Christopher S Waters, R. Coleman Lindsley, MDPhD, Benjamin L. Ebert, MD
Journal: Blood
Blood (2015) 126 (23): 356.
https://doi.org/10.1182/blood.V126.23.356.356
Published: 2015
Journal Articles

A Proteomics Screen Identifies MDM2 Binding Partners Specific to Ribosomal Protein Haploinsufficiency

David M. Raiser, BS, Monica Schenone, Emily Hartman, Steven A. Carr, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1597.
https://doi.org/10.1182/blood.V124.21.1597.1597
Published: 2014
Journal Articles

Lenalidomide Promotes CRBN-Mediated Ubiquitination and Degradation of IKZF1 and IKZF3

Jan Krönke, Namrata Udeshi, Anupama Narla, Peter Grauman, Slater Hurst, Marie McConkey, Tanya Svinkina, Dirk Heckl, Eamon Comer, Xiaoyu Li, Christie Ciarlo, Emily Hartman, Monica Schenone, Stuart Schreiber, Steven A. Carr, Benjamin L. Ebert
Journal: Blood
Blood (2013) 122 (21): LBA-5.
https://doi.org/10.1182/blood.V122.21.LBA-5.LBA-5
Published: 2013
Journal Articles

Inhibition of the CRBN-DDB1-CUL4-ROC1 E3 Ubiquitin Ligase Mediates the Anti-Proliferative and Immunomodulatory Properties of Lenalidomide

Jan Krönke, Anupama Narla, Slater N. Hurst, Namrata Udeshi, Monica Schenone, Marie McConkey, Peter Grauman, Dirk Heckl, Randall McAuley, Christie Ciarlo, Eamon Comer, Xiaoyu Li, Steven A. Carr, Benjamin L. Ebert
Journal: Blood
Blood (2012) 120 (21): 919.
https://doi.org/10.1182/blood.V120.21.919.919
Published: 2012
Journal Articles

Identification of Inducers of Megakaryocyte Polyploidization and Their Use as Targeted Differentiation Therapy for Acute Megakaryocytic Leukemia.

Qiang Wen, PhD, MD, Zan Huang, PhD, Sara Small, Niket Bubna, Frank An, PhD, Meghan Bliss-Moreau, Lynn Verplank, PhD, Tim Lewis, PhD, Monica Schenone, PhD, Nicola Tolliday, PhD, Chris Moore, Ann Carpenter, PhD, Thomas Mercher, Ph.D, Ross L. Levine, MD, Shai Izraeli, MD, Andrew Stern, PhD, Robert Gould, PhD, James E. Bradner, MD, John Crispino, PhD
Journal: Blood
Blood (2009) 114 (22): 792.
https://doi.org/10.1182/blood.V114.22.792.792
Published: 2009