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Journal Articles

Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)

Junjing Qiao, MD PhD, Dandan Zhao, MD, Le Xuan Truong Nguyen, PhD, Herman Wu, BS, Gang Liu, PhD, Shanshan Suo, MD, Huafeng Wang, Yasmin Elhajmoussa, Chen Liang, MD, David Snyder, MD, Haris Ali, MD, Steven Rosen, MD, Nadia Carlesso, MD, Ling Li, PhD, Ya-Huei Kuo, PhD, Guido Marcucci, MD, Bin Zhang, PhD

Blood (2019) 134 (Supplement_1): 3791.

https://doi.org/10.1182/blood-2019-127616

Published: 2019

Journal Articles

FLT3-ITD Activates Cytoplasmic Drosha-Dependent Non-Canonical Mechanisms of Mir-155 Biogenesis in Acute Myeloid Leukemia

Le Xuan Truong Nguyen, PhD, Bin Zhang, PhD, Dinh Hoa Hoang, BS, Dandan Zhao, MD, Sergio Branciamore, Davide Maestrini, PhD, Yu-Lin SU, PhD, Sonia Rodriguez, PhD, Flavia Pichiorri, PhD, Steven Rosen, MD, Michael A. Caligiuri, MD, Stephen J. Forman, MD, Ling Li, PhD, Marcin Kortylewski, PhD, Russell Rockne, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD, Guido Marcucci, MD

Blood (2019) 134 (Supplement_1): 2722.

https://doi.org/10.1182/blood-2019-131871

Published: 2019

Journal Articles

Targeting MiR-126 Blocks Progression of Myelodysplastic Syndrome and Transformation into Acute Myeloid Leukemia

Huafeng Wang, MD, Jie Sun, PhD, Dandan Zhao, MD, Hongyan Tong, Herman Wu, BS, Xia Li, PhD, Yingwan Luo, MD, Dan Dong, PhD, Tinisha McDonald, MS, Anthony Stein, MD, Monzr M. Al Malki, MD, Flavia Pichiorri, PhD, Nadia Carlesso, MD, Ya-Huei Kuo, PhD, Bin Zhang, PhD, Guido Marcucci, MD, Ling Li, PhD, Jie Jin, MD PhD

Blood (2019) 134 (Supplement_1): 1707.

https://doi.org/10.1182/blood-2019-130375

Published: 2019

Journal Articles

Inhibition of PRMT1 Mediated FLT3 Arginine Methylation As a Potent Therapeutic Strategy for MLL-r ALL

Yinghui Zhu, PhD, Xin He, PhD, Haojie Dong, PhD, Jie Sun, PhD, Hanying Wang, PhD, Lei Zhang, PhD, Yunan Miao, PhD, Jian Jin, PhD, Yudao Shen, PhD, Jianjun Chen, PhD, Markus Muschen, MD, Chun-Wei Chen, PhD, Marina Y. Konopleva, MD PhD, Weili Sun, MD PhD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD PhD, Guido Marcucci, Ling Li, PhD

Blood (2018) 132 (Supplement 1): 892.

https://doi.org/10.1182/blood-2018-99-115139

Published: 2018

Journal Articles

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Blood (2018) 132 (Supplement 1): 760.

https://doi.org/10.1182/blood-2018-99-112766

Published: 2018

Journal Articles

Rap1 Gtpases Regulate the Retention and Engraftment of Hematopoietic Stem and Progenitor Cells

Baskar Ramdas, PhD, Joydeep Ghosh, PhD, Raghuveer Singh Mali, PhD, Zollman Amy, Nadia Carlesso, MD PhD, Malgorzata Kamocka M, Dunn W Kenneth, PhD, Lawrance Quilliam, PhD, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 326.

https://doi.org/10.1182/blood-2018-99-117197

Published: 2018

Journal Articles

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Blood (2018) 132 (Supplement 1): 1338.

https://doi.org/10.1182/blood-2018-99-119599

Published: 2018

Journal Articles

Defective Notch Activation in Mesenchymal Cells Contributes to Myeloproliferative Neoplasm in Aged Mice

Young-Woong Kim, PhD, Sonia Rodriguez, PhD, Lin Wang, PhD, Guido Marcucci, MD, Amy Zollman, Nadia Carlesso, MD PhD

Blood (2017) 130 (Supplement 1): 134.

https://doi.org/10.1182/blood.V130.Suppl_1.134.134

Published: 2017

Journal Articles

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

Blood (2017) 130 (Supplement 1): 1361.

https://doi.org/10.1182/blood.V130.Suppl_1.1361.1361

Published: 2017

Journal Articles

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Jihane Khalife, Domenico Viola, BS, Jayeeta Ghose, Robert Weingart, James F Sanchez, Craig C Hofmeister, MDMPH, Amrita Krishnan, MD, Guido Marcucci, MD, Nadia Carlesso, MD PhD, Enrico Caserta, PhD, Flavia Pichiorri, PhD

Blood (2017) 130 (Supplement 1): 4351.

https://doi.org/10.1182/blood.V130.Suppl_1.4351.4351

Published: 2017

Journal Articles

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Blood (2017) 130 (Supplement 1): 2497.

https://doi.org/10.1182/blood.V130.Suppl_1.2497.2497

Published: 2017

Journal Articles

Reacting to Inflammatory Signals

Nadia Carlesso, MD PhD

Blood (2015) 126 (23): SCI-30.

https://doi.org/10.1182/blood.V126.23.SCI-30.SCI-30

Published: 2015

Journal Articles

Bidirectional Notch Signaling Between Multiple Myeloma (MM) Cells and Osteocytes As a Potential Target to Inhibit Tumor Growth and Osteoclast Recruitment in MM

Jesus Delgado-Calle, PhD, Judith Anderson, Meloney D. Cregor, Nadia Carlesso, MD PhD, Khalid S. Mohammad, MD PhD, Lilian I. Plotkin, PhD, Teresita M. Bellido, PhD, G. David Roodman, MD PhD

Blood (2015) 126 (23): 2977.

https://doi.org/10.1182/blood.V126.23.2977.2977

Published: 2015

Journal Articles

SKP2 Is Dispensable for Normal T-Cell Development but Required for T-Cell Leukemogenesis

Sonia Rodriguez-Rodriguez, PhD, Lin Wang, PhD, Huajia Zhang, PhDstudent, Amy Zollman, BS, Angelo A. Cardoso, Nadia Carlesso, MD PhD

Blood (2014) 124 (21): 2214.

https://doi.org/10.1182/blood.V124.21.2214.2214

Published: 2014

Journal Articles

Activation Of TLR4-MyD88 Pathway Impairs HSC Function During Acute Inflammation

Huajia Zhang, BS, Sonia Rodriguez-Rodriguez, PhD, Lin Wang, PhD, Christen Mumaw, BS, Amy Zollman, BS, Yunlong Liu, Angelo A. Cardoso, MD, PhD, Nadia Carlesso, MD, PhD

Blood (2013) 122 (21): 2431.

https://doi.org/10.1182/blood.V122.21.2431.2431

Published: 2013

Journal Articles

Absence Of The E3 Ubiquitin Ligase SKP2 Attenuates Notch-Induced T-Cell Leukemogenesis

Sonia Rodriguez-Rodriguez, PhD, Lin Wang, PhD, Huajia Zhang, BS, Amy Zollman, BS, Angelo Cardoso, MD, PhD, Nadia Carlesso, MD, PhD

Blood (2013) 122 (21): 1272.

https://doi.org/10.1182/blood.V122.21.1272.1272

Published: 2013

Journal Articles

Loss Of Canonic Notch Signaling In The Microenvironment Causes a Myeloproliferative Syndrome Via Derepression Of The miR155 Promoter

Lin Wang, PhD, Huajia Zhang, BS, Sonia Rodriguez-Rodriguez, PhD, Liyun Cao, PhD, Jonathan Parish, BS, Amy Zollman, BS, Malgorzata Kamocka, PhD, H. Scott Boswell, M.D., Edward F. Srour, Ph.D., Brahmananda Reddy Chitteti, PhD, Taghi Manshouri, Ph.D., Srdan Verstovsek, MD, PhD, Reuben Kapur, PhD, Angelo A. Cardoso, MD, PhD, Nadia Carlesso, MD, PhD

Blood (2013) 122 (21): 339.

https://doi.org/10.1182/blood.V122.21.339.339

Published: 2013

Journal Articles

Regulation of Hematopoietic Cell Engraftment and Myeloid Differentiation by the E3 Ubiquitin Ligase F-Box Protein SKP2,

Sonia Rodriguez-Rodriguez, PhD, Declan McGuigan, Student, Lin Wang, PhD, Christen Mumaw, BS, Nadia Carlesso, MD, PhD

Blood (2011) 118 (21): 3397.

https://doi.org/10.1182/blood.V118.21.3397.3397

Published: 2011

Journal Articles

STAT3 Is Required for Notch-Induced Leukemogenesis, and Functions As a Critical Survival Effector in T-Cell Leukemia

Jixin Ding, PhD, Ana L. Batista, PhD, Sonia Rodriguez-Rodriguez, PhD, Lin Wang, PhD, Wenjun Zhang, PhD, Akira Moh, PhD, Xin-Yuan Fu, PhD, Weinian Shou, PhD, Nadia Carlesso, MD, PhD, Angelo A Cardoso, MD, PhD

Blood (2011) 118 (21): 920.

https://doi.org/10.1182/blood.V118.21.920.920

Published: 2011

Journal Articles

Activation of the Canonical Notch Signaling Pathway in the Hematopoietic Microenvironment Is Required to Maintain Normal Hematopoiesis

Lin Wang, PhD, Sonia Rodriguez-Rodriguez, PhD, Huajia Zhang, PhD student, Christen Mumaw, BS, Angelo A Cardoso, MD, PhD, Nadia Carlesso, MD, PhD

Blood (2011) 118 (21): 723.

https://doi.org/10.1182/blood.V118.21.723.723

Published: 2011

NARROW

Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)

FLT3-ITD Activates Cytoplasmic Drosha-Dependent Non-Canonical Mechanisms of Mir-155 Biogenesis in Acute Myeloid Leukemia

Targeting MiR-126 Blocks Progression of Myelodysplastic Syndrome and Transformation into Acute Myeloid Leukemia

Inhibition of PRMT1 Mediated FLT3 Arginine Methylation As a Potent Therapeutic Strategy for MLL-r ALL

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Rap1 Gtpases Regulate the Retention and Engraftment of Hematopoietic Stem and Progenitor Cells

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Defective Notch Activation in Mesenchymal Cells Contributes to Myeloproliferative Neoplasm in Aged Mice

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Reacting to Inflammatory Signals

Bidirectional Notch Signaling Between Multiple Myeloma (MM) Cells and Osteocytes As a Potential Target to Inhibit Tumor Growth and Osteoclast Recruitment in MM

SKP2 Is Dispensable for Normal T-Cell Development but Required for T-Cell Leukemogenesis

Activation Of TLR4-MyD88 Pathway Impairs HSC Function During Acute Inflammation

Absence Of The E3 Ubiquitin Ligase SKP2 Attenuates Notch-Induced T-Cell Leukemogenesis

Loss Of Canonic Notch Signaling In The Microenvironment Causes a Myeloproliferative Syndrome Via Derepression Of The miR155 Promoter

Regulation of Hematopoietic Cell Engraftment and Myeloid Differentiation by the E3 Ubiquitin Ligase F-Box Protein SKP2,

STAT3 Is Required for Notch-Induced Leukemogenesis, and Functions As a Critical Survival Effector in T-Cell Leukemia

Activation of the Canonical Notch Signaling Pathway in the Hematopoietic Microenvironment Is Required to Maintain Normal Hematopoiesis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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