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Journal Articles

Clinical Utility of Plasma Cell-Free DNA for Detection and Quantification of Clonal Hematopoiesis

Fernanda Gutierrez-Rodrigues, PhD, Isabel Beerman, PhD, Emma M. Groarke, MD, Bhavisha A Patel, MD, Nina Spitofsky, Diego Quinones Raffo, MSc, Sachiko Kajigaya, PhD, Luigi Ferrucci, MD PhD, Neal S. Young, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-139874

Published: 2020

Journal Articles

Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron

David J Young, MDPhD, Xing Fan, MD, Emma Groarke, MD, Bhavisha A Patel, MD, Ronan Desmond, MD, Thomas Winkler, MD, Andre Larochelle, MD PhD, Katherine R. Calvo, MD PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-141375

Published: 2020

Journal Articles

Myelodysplasia and Bone Marrow Manifestations of Somatic UBA1 Mutated Autoinflammatory Disease

Ifeyinwa Emmanuela Obiorah, MBBS,PhD, David B. Beck, MDPhD, Weixin Wang, PhD, Amanda Ombrello, MD, Marcela A Ferrada, MD, Zhijie Wu, MD, Keith A Sikora, MD, Megan A Trick, Alina Dulau-Florea, MD, Bhavisha A Patel, MD, Emma Groarke, MD, Shawn M. Burgess, PhD, Achim A Werner, PhD, Ivona A Aksentijevich, MD, Neal S. Young, MD, Daniel L Kastner, MDPhD, Peter C Grayson, MD, Katherine R. Calvo, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-140480

Published: 2020

Journal Articles

Somatic Mutations in a Single Residue of UBA1 Cause Vexas, a Severe Adult-Onset Rheumatic Disease Associated with Myeloid Dysplasia

David B. Beck, MDPhD, Zhijie Wu, MD, Bhavisha A Patel, MD, Marcela A Ferrada, MD, Keith A Sikora, MD, Amanda Ombrello, MD, Alina E. Dulau Florea, MD, Weixin Wang, PhD, Emma M. Groarke, MD, Shawn M. Burgess, PhD, Ivona A Aksentijevich, MD, Achim A Werner, PhD, Neal S. Young, MD, Katherine R. Calvo, MD PhD, Daniel L Kastner, MDPhD, Peter C Grayson, MD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-141949

Published: 2020

Journal Articles

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Bhavisha A Patel, MD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 1219.

https://doi.org/10.1182/blood-2019-127053

Published: 2019

Journal Articles

Analysis of Deficiency of Adenosine Deaminase 2 Pathogenesis Based on Single Cell RNA Sequencing of Monocytes

Naoki Watanabe, Shouguo Gao, PhD, Sachiko Kajigaya, Carrie Diamond, MD, Lemlem Alemu, BS, Amanda Ombrello, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 2317.

https://doi.org/10.1182/blood-2019-123859

Published: 2019

Journal Articles

Outcomes in Pediatric Patients with Severe Aplastic Anemia Treated with Standard Immunosuppression and Eltrombopag

Emma M. Groarke, MD, Bhavisha A Patel, MD, Carrie Diamond, MD, Fernanda Gutierrez-Rodrigues, PhD, Alana Vicente, MD, Olga Rios, RN, Jennifer Lotter, PA-C, Daniela Baldoni, Ruba Shalhoub, Colin Wu, PhD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 454.

https://doi.org/10.1182/blood-2019-124811

Published: 2019

Journal Articles

T Cell Landscape of Immune Aplastic Anemia Reveals a Convergent Antigen-Specific Signature

Jani Huuhtanen, BMed, Sofie Lundgren, BMed, Mikko A Keränen, MD PhD, Xingmin Feng, PhD, Cassandra M Kerr, MS, Emmi Jokinen, MSc, Markus Heinonen, PhD, Paula Savola, MD PhD, Tiina Kelkka, PhD, Freja Ebeling, MD PhD, Georgina L Ryland, Lucy Fox, Piers Blombery, MBBS, Eva Hellstrom Lindberg, MD PhD, Neal S. Young, MD, Jaroslaw P. Maciejewski, MD PhD, Harri Lähdesmäki, PhD, Satu Mustjoki, MD PhD

Blood (2019) 134 (Supplement_1): 108.

https://doi.org/10.1182/blood-2019-127790

Published: 2019

Journal Articles

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Shouguo Gao, PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3706.

https://doi.org/10.1182/blood-2019-123204

Published: 2019

Journal Articles

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Zhijie Wu, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Jinguo Chen, PhD, Rongye Shi, BS, Carrie Diamond, MD, Cindy Palmer, BSN, Amy P. Hsu, Katherine R. Calvo, MD PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3735.

https://doi.org/10.1182/blood-2019-124774

Published: 2019

Journal Articles

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Sharon D. Adams, MT, CHS (ABHI), Bhavisha A Patel, MD, Audrey Ai Chin Lee, MS, CHT (ABHI), Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Olga Rios, RN, Holly DiFebo, RN, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Willy A. Flegel, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3738.

https://doi.org/10.1182/blood-2019-127359

Published: 2019

Journal Articles

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Xin Zhao, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Qingguo Liu, MD PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Fengkui Zhang, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 4997.

https://doi.org/10.1182/blood-2019-123249

Published: 2019

Journal Articles

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Shouguo Gao, PhD, Zhijie Wu, MD PhD, Carrie Diamond, MD, Bradley Arnold, BS, Valentina Giudice, MD, Lemlem Alemu, BS, John Barrett, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2404.

https://doi.org/10.1182/blood-2018-99-115166

Published: 2018

Journal Articles

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Fernanda Gutierrez-Rodrigues, PhD, Carrie Diamond, MD, Ruba Shalhoub, André Pinto, Flávia S Donaires, PhD, Diego V Clé, MD PhD, Luiz Guilherme Darrigo, PhD, Luiz Fernando Catto, MD, Xing Fan, MD, Maria del Pilar Fernandez Ibanez, Sachiko Kajigaya, PhD, Cynthia E. Dunbar, MD, Carmem M. S. Bonfim, MD, Danielle M. Townsley, MD MSc, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2587.

https://doi.org/10.1182/blood-2018-99-115026

Published: 2018

Journal Articles

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Fernanda Gutierrez-Rodrigues, PhD, Flávia S Donaires, PhD, André Pinto, Alana Vicente, MD, Laura Dillon, PhD, Diego V Clé, MDPhD, Bárbara Santana, Maria del Pilar Fernandez Ibanez, Danielle M. Townsley, MD MSc, Sachiko Kajigaya, PhD, Christopher S. Hourigan, DPhil FACP FRCP, James N. Cooper, MD, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 539.

https://doi.org/10.1182/blood-2018-99-115430

Published: 2018

Journal Articles

Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS)

Alana Vicente, MD, Fernanda Gutierrez-Rodrigues, PhD, Valentina Giudice, MD, Zhijie Wu, MD PhD, Sachiko Kajigaya, PhD, Maria del Pilar Fernandez Ibanez, Maher Albitar, MD, Barbara Weinstein, RN, Katherine R. Calvo, MD PhD, Danielle M. Townsley, MDMSc, Phillip Scheinberg, MD, Cynthia E. Dunbar, MD, Neal S. Young, MD, Thomas Winkler, MD

Blood (2018) 132 (Supplement 1): 229.

https://doi.org/10.1182/blood-2018-99-119780

Published: 2018

Journal Articles

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Xing Fan, MD, Thomas Winkler, MD, Ronan Desmond, MD, Bogdan Dumitriu, MD, Danielle M. Townsley, MD MSc, Maria del Pilar Fernandez Ibanez, Fernanda Gutierrez-Rodrigues, PhD, Sophia Grasmeder, RN, Ma Evette Barranta, Diane Madey, Jennifer Lotter, Janet Valdez, Katherine R. Calvo, MD PhD, Colin Wu, PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 538.

https://doi.org/10.1182/blood-2018-99-112994

Published: 2018

Journal Articles

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Xingmin Feng, PhD, Zenghua Lin, MD, Maile K. Hollinger, BA, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Kaylind Batey, BS, Keyvan Keyvanfar, BS, Jichun Chen, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 1310.

https://doi.org/10.1182/blood-2018-99-113488

Published: 2018

Journal Articles

Eltrombopag for Refractory Severe Aplastic Anemia: Dosing Regimens, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Thomas Winkler, MD, James N. Cooper, MD, Danielle M. Townsley, MDMSc, Phillip Scheinberg, MD, Sophia Grasmeder, RN, Colin Wu, PhD, Jennifer Lotter, Marie J Desierto, MS, Ronan Desmond, MD, Matthew J. Olnes, MD PhD, Katherine R Calvo, MD PhD, Neal S. Young, MD, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 777.

https://doi.org/10.1182/blood.V130.Suppl_1.777.777

Published: 2017

Journal Articles

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

Xingmin Feng, PhD, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Zenghua Lin, MD, Maile K Hollinger, BA, Jichun Chen, PhD, Neal S. Young, MD

Blood (2017) 130 (Supplement 1): 778.

https://doi.org/10.1182/blood.V130.Suppl_1.778.778

Published: 2017

NARROW

Clinical Utility of Plasma Cell-Free DNA for Detection and Quantification of Clonal Hematopoiesis

Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron

Myelodysplasia and Bone Marrow Manifestations of Somatic UBA1 Mutated Autoinflammatory Disease

Somatic Mutations in a Single Residue of UBA1 Cause Vexas, a Severe Adult-Onset Rheumatic Disease Associated with Myeloid Dysplasia

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Analysis of Deficiency of Adenosine Deaminase 2 Pathogenesis Based on Single Cell RNA Sequencing of Monocytes

Outcomes in Pediatric Patients with Severe Aplastic Anemia Treated with Standard Immunosuppression and Eltrombopag

T Cell Landscape of Immune Aplastic Anemia Reveals a Convergent Antigen-Specific Signature

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS)

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Eltrombopag for Refractory Severe Aplastic Anemia: Dosing Regimens, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

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American Society of Hematology

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American Society of Hematology

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