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Journal Articles

TLR-9 and B-Cell Antigen Receptor Triggering of Primary B Cells From Mantle Cell Lymphoma Induce Cell Proliferation and Telomerase Activity,

Sonal Temburni, MS, Ryon M. Andersen, B.A., Steven L. Allen, M.D., Jaqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D., Rajendra N Damle, PhD

Blood (2011) 118 (21): 3690.

https://doi.org/10.1182/blood.V118.21.3690.3690

Published: 2011

Journal Articles

Co-Culture of CLL Cells with MEACs (Myosin Heavy Chain IIA Exposed Apoptotic Cells) Promotes Viability of Leukemic Clones

Charles C. Chu, Ph.D., Xiaoxuan Cui, M.D., Ph.D., Rosa Catera, Ph.D., Lu Zhang, M.S., Amanda R. Magli, B.S.E., Xiao-Jie Yan, M.D., Ph.D., Jonathan E. Kolitz, MD, Steven L. Allen, M.D., Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 624.

https://doi.org/10.1182/blood.V118.21.624.624

Published: 2011

Journal Articles

Longitudinal Analyses of CXCR4 dim CD5 br CD19 + Fractions of Chronic Lymphocytic Leukemia Clones Reveal Features Consistent with a Source of Clonal Heterogeneity

Rajendra N Damle, PhD, Carlo Calissano, MD, Sonal Temburni, MS, Ryon M. Andersen, B.A., Steven L. Allen, M.D., Jonathan E. Kolitz, MD, Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 804.

https://doi.org/10.1182/blood.V118.21.804.804

Published: 2011

Journal Articles

Engraftment of CLL-Derived T Cells in NSG Mice Is Feasible, Can Support CLL Cell Proliferation, and Eliminates the Need for Third Party Antigen Presenting Cells

Piers EM Patten, BSc, MBBCh, PhD, Shih-Shih Chen, Ph.D., Davide Bagnara, Ph.D., Rita Simone, PhD, Sonia Marsilio, PhD, Timothy Tong, Jaqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, M.D., Kanti R Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 975.

https://doi.org/10.1182/blood.V118.21.975.975

Published: 2011

Journal Articles

Btk Inhibitor, PCI-32765, Delays CLL Progression in a TCL1 Adoptive Transfer Model by Impairing Migration and Cell Proliferation

Shih-Shih Chen, Ph.D., Joseph J. Buggy, PhD, Betty Y Chang, PhD, Jan A. Burger, MD, PhD, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 982.

https://doi.org/10.1182/blood.V118.21.982.982

Published: 2011

Journal Articles

Effect of Polymorphisms in p53 Pathway Proteins and B-Chronic Lymphocytic Leukemia Disease Progression,

Hyunjoo Lee, Anthony Liew, Annette Lee, PhD, Shabirul Haque, Ph.D., Jonathan E Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, M.D., Peter Gregersen, MD, Charles C. Chu, Ph.D., Nicholas Chiorazzi, M.D., Patricia Mongini, Ph.D.

Blood (2011) 118 (21): 3888.

https://doi.org/10.1182/blood.V118.21.3888.3888

Published: 2011

Journal Articles

Influence of PGE 2 on Expression of a Functionally-Relevant p53 SNP (Pro72Arg) within Heterozygous Normal Cycling B Cells,

Shabirul Haque, Ph.D., Hyunjoo Lee, Jennifer Nieto, Nicholas Chiorazzi, M.D., Patricia Mongini, Ph.D.

Blood (2011) 118 (21): 3234.

https://doi.org/10.1182/blood.V118.21.3234.3234

Published: 2011

Journal Articles

Evidence for Allelic Exclusion of p53 within Single Sorted Human B Cells

Shabirul Haque, Ph.D., Jennifer Nieto, Hyunjoo Lee, Nicholas Chiorazzi, M.D., Patricia Mongini, Ph.D.

Blood (2011) 118 (21): 1122.

https://doi.org/10.1182/blood.V118.21.1122.1122

Published: 2011

Journal Articles

Chronic Lymphocytic Leukemia Patients with IGHV Genes Carrying Only Silent Mutations Have A Longer Time From Diagnosis to Initial Therapy Than Patients Expressing B-Cell Receptors with No Somatic Mutations

Matthew Kaufman, MD, Xiao J. Yan, MD, PhD, Emanuela M. Ghia, PhD, Donna Neuberg, ScD, Laura Z. Rassenti, Ph.D., Kostas Stamatopoulos, MD, Paolo Ghia, MD, PhD, David G Oscier, MD, Frederic Davi, MD, PhD, Richard Rosenquist, MD, PhD, Chrysoula Belessi, MD, Zadie Davis, PhD, Andreas Agathangelidis, Neil Kay, MD, John C. Byrd, MD, Jennifer R Brown, MD, PhD, Kanti R. Rai, M.D., Thomas J. Kipps, M.D., Ph.D, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 288.

https://doi.org/10.1182/blood.V118.21.288.288

Published: 2011

Journal Articles

Gene Set Enrichment Analysis of Ki-67 high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease

Xiao J. Yan, MD, PhD, Daniel Kalenscher, Erin Boyle, Sophia Yancopoulos, PhD, Rajendra N Damle, PhD, Aarti Damle, Houman Khalili, Annette Lee, PhD, Wentian Li, Ph.D., Igor Dozmorov, MD, PhD, Matthew Kaufman, M.D., Peter Gregersen, MD, Steven L. Allen, M.D., Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 2833.

https://doi.org/10.1182/blood.V118.21.2833.2833

Published: 2011

Journal Articles

Targeted Oligonucleotide Array Assessment of Genomic Copy Number Alterations for Risk Stratification in Chronic Lymphocytic Leukemia

Jane Houldsworth, PhD, Asha Guttapalli, MS, Xiao J. Yan, MD, PhD, Charles Ma, PhD, Weiyi Chen, PhD, Sujata Patil, PhD, Kanti R Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 1773.

https://doi.org/10.1182/blood.V118.21.1773.1773

Published: 2011

Journal Articles

Differential Expression Genes of CLL Subgroups Defined by Ki67 Expression Level Which Correlated with Clinical Outcome

Xiao-Jie Yan, M.D., Ph.D., Daniel Kalenscher, Erin Boyle, Arrti Damle, Sophie Yancopoulos, Ph.D., Rajendra N Damle, PhD, Houman Khalili, Annette Lee, PhD, Wentian Li, Ph.D., Igor Dozmorov, MD, PhD, Matthew Kaufman, M.D., Peter Gregersen, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2010) 116 (21): 2435.

https://doi.org/10.1182/blood.V116.21.2435.2435

Published: 2010

Journal Articles

Identification of Distinct Cytokine and Chemokine Clusters That Correlate with Outcome In B-Cell Chronic Lymphocytic Leukemia: Implications for Disease Pathogenesis

Xiao-Jie Yan, M.D., Ph.D., Wentian Li, Sophie Yancopoulos, PhD, Igor Dozmorov, MD, PhD, Michael Centola, MD, Steven L. Allen, MD, Kanti R Rai, MD, Nicholas Chiorazzi, M.D., Barbara Sherry, PhD

Blood (2010) 116 (21): 1368.

https://doi.org/10.1182/blood.V116.21.1368.1368

Published: 2010

Journal Articles

Murine TCL1 CLL Cells with B-Cell Receptors Specific for the Autoantigen Phosphatidylcholine Have a Selective Advantage During Adoptive Transfer

Shih-Shih Chen, Ph.D., Franak Batliwalla, Ph.D., Nichol Holodick, Ph.D., Xiao-Jie Yan, M.D., Ph.D., Thomas L. Rothstein, M.D., Ph.D., Nicholas Chiorazzi, M.D.

Blood (2010) 116 (21): 373.

https://doi.org/10.1182/blood.V116.21.373.373

Published: 2010

Journal Articles

Efficacy and Safety of Hydroxychloroquine Sulphate In Chronic Lymphocytic Leukemia: Clinical Trial Experience In Untreated Patients

Shih-Shih Chen, Ph.D., Matthew Kaufman, M.D., Angelica Caramanica, Rajendra N Damle, Ph.D., Peter Garofalo, Patricia Ly, Dale Janson, Steven L. Allen, M.D., Jonathan Kolitz, M.D., Linda Quill, Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2010) 116 (21): 1392.

https://doi.org/10.1182/blood.V116.21.1392.1392

Published: 2010

Journal Articles

Elevated Binding of Chronic Lymphocytic Leukemia Antibody to a Subset of Apoptotic Cells with Exposed Non-Muscle Myosin Heavy Chain IIA Correlates with Poor Patient Outcome.

Charles C. Chu, Ph.D., Rosa Catera, Ph.D., Lu Zhang, M.A., Briana M. Agagnina, Sebastien Didier, M.S., Jonathan E. Kolitz, M.D., Steven L. Allen, M.D., Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2009) 114 (22): 799.

https://doi.org/10.1182/blood.V114.22.799.799

Published: 2009

Journal Articles

Expression Levels of a Single Gene, Lymphoid Enhancer Binding Factor 1, Discriminates CLL B-Cells from Other B-Cell Malignancies.

Brian A. McCarthy, PhD, Mike Tipping, Ph.D., Xue Ping Wang, Ph.D., Fiona Bennet, Ph.D., Wentian Li, Ph.D., Martin Lesser, Ph.D., Santanu Paul, Ph.D., Erin Boyle, B.S., Carol Moreno, Ph.D., Rosa Catera, Ph.D., Bradley T. Messmer, Ph.D., Steven L. Allen, M.D., Andrew C. Rawstron, M.D., Kanti R. Rai, M.D, Nicholas Chiorazzi, M.D.

Blood (2007) 110 (11): 1113.

https://doi.org/10.1182/blood.V110.11.1113.1113

Published: 2007

Journal Articles

B-CLL Antibodies Encoded by Stereotypic V H 1-69 , D3-16 , and J H 3 Rearrangements Immunoprecipitate Non-Muscle Myosin Heavy Chain IIA.

Charles C. Chu, PhD, Lu Zhang, Katerina Hatzi, Rosa Catera, Ph.D., Steven L. Allen, M.D., Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2007) 110 (11): 739.

https://doi.org/10.1182/blood.V110.11.739.739

Published: 2007

Journal Articles

B-CLL Antibodies Comprised of Stereotypic V H 1-69, D3-16, and J H 3 Rearrangements Immunoprecipitate Cellular Protein(s).

Charles C. Chu, PhD, Xiao Bo Wang, M.D., Katerina Hatzi, Rosa Catera, Ph.D., Eric Meffre, Ph.D., Maxime Herve, Steven L. Allen, M.D., Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2006) 108 (11): 2816.

https://doi.org/10.1182/blood.V108.11.2816.2816

Published: 2006

Journal Articles

Genome Analysis of CLL by Representational Oligonucleotide Microarray Analysis (ROMA).

Vladimir D. Grubor, PhD, Jennifer E. Troge, B.S, Jennifer L. Meth, B.S., B. Lakshmi, Ph.D., Boris Yamron, Ph.D., Lisa A. Hufnagel, M.S., Yoon-Ha Lee, Ph.D., Jude T. Kendall, B.S., Deepa Pai, M.S., Annette Lee, Ph.D., Peter Gregersen, M.D., Sophia Yancopoulos, Ph.D., Steven Allen, M.D., Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D., Michael H. Wigler, Ph.D., Diane Esposito, Ph.D.

Blood (2006) 108 (11): 2085.

https://doi.org/10.1182/blood.V108.11.2085.2085

Published: 2006

NARROW

TLR-9 and B-Cell Antigen Receptor Triggering of Primary B Cells From Mantle Cell Lymphoma Induce Cell Proliferation and Telomerase Activity,

Co-Culture of CLL Cells with MEACs (Myosin Heavy Chain IIA Exposed Apoptotic Cells) Promotes Viability of Leukemic Clones

Longitudinal Analyses of CXCR4 dim CD5 br CD19 + Fractions of Chronic Lymphocytic Leukemia Clones Reveal Features Consistent with a Source of Clonal Heterogeneity

Engraftment of CLL-Derived T Cells in NSG Mice Is Feasible, Can Support CLL Cell Proliferation, and Eliminates the Need for Third Party Antigen Presenting Cells

Btk Inhibitor, PCI-32765, Delays CLL Progression in a TCL1 Adoptive Transfer Model by Impairing Migration and Cell Proliferation

Effect of Polymorphisms in p53 Pathway Proteins and B-Chronic Lymphocytic Leukemia Disease Progression,

Influence of PGE 2 on Expression of a Functionally-Relevant p53 SNP (Pro72Arg) within Heterozygous Normal Cycling B Cells,

Evidence for Allelic Exclusion of p53 within Single Sorted Human B Cells

Chronic Lymphocytic Leukemia Patients with IGHV Genes Carrying Only Silent Mutations Have A Longer Time From Diagnosis to Initial Therapy Than Patients Expressing B-Cell Receptors with No Somatic Mutations

Gene Set Enrichment Analysis of Ki-67 high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease

Targeted Oligonucleotide Array Assessment of Genomic Copy Number Alterations for Risk Stratification in Chronic Lymphocytic Leukemia

Differential Expression Genes of CLL Subgroups Defined by Ki67 Expression Level Which Correlated with Clinical Outcome

Identification of Distinct Cytokine and Chemokine Clusters That Correlate with Outcome In B-Cell Chronic Lymphocytic Leukemia: Implications for Disease Pathogenesis

Murine TCL1 CLL Cells with B-Cell Receptors Specific for the Autoantigen Phosphatidylcholine Have a Selective Advantage During Adoptive Transfer

Efficacy and Safety of Hydroxychloroquine Sulphate In Chronic Lymphocytic Leukemia: Clinical Trial Experience In Untreated Patients

Elevated Binding of Chronic Lymphocytic Leukemia Antibody to a Subset of Apoptotic Cells with Exposed Non-Muscle Myosin Heavy Chain IIA Correlates with Poor Patient Outcome.

Expression Levels of a Single Gene, Lymphoid Enhancer Binding Factor 1, Discriminates CLL B-Cells from Other B-Cell Malignancies.

B-CLL Antibodies Encoded by Stereotypic V H 1-69 , D3-16 , and J H 3 Rearrangements Immunoprecipitate Non-Muscle Myosin Heavy Chain IIA.

B-CLL Antibodies Comprised of Stereotypic V H 1-69, D3-16, and J H 3 Rearrangements Immunoprecipitate Cellular Protein(s).

Genome Analysis of CLL by Representational Oligonucleotide Microarray Analysis (ROMA).

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American Society of Hematology

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American Society of Hematology

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