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Journal Articles

Fat Mass Obesity-Associated (FTO) Driven Gene Regulatory Networks Control Hematopoietic Stem Cell Expansion and Homing

Ajay Ratan Pasala, Tanvir Hassan, Nicolas Pineault, Harinad Maganti

Blood (2024) 144 (Supplement 1): 2652.

https://doi.org/10.1182/blood-2024-200374

Published: 2024

Journal Articles

Loss of Autophagy Activity during Storage of Hematopoietic Stem Cell Grafts Is Associated with Reduced Potency

Harinad Maganti, Suria Jahan, Jaina Patel, Richa Kaushal, Chelsea Mcgregor, Roya Pasha, Nicolas Pineault

Blood (2023) 142 (Supplement 1): 6792.

https://doi.org/10.1182/blood-2023-187210

Published: 2023

Journal Articles

GAS6 Promotes Robust Expansion of Human Hematopoietic Stem and Progenitor Cells with High Serial Engraftment Activity

Harinad B Maganti, Javed Manesia, Tanvir Hasan, Chelasea Mcgregor, Roya Pasha, David Allan, Julie Audet, Nicolas Pineault

Blood (2022) 140 (Supplement 1): 1979–1980.

https://doi.org/10.1182/blood-2022-169206

Published: 2022

Journal Articles

Stringent Small Molecule Dose Requirements for the Optimal Expansion of Hematopoietic Stem Cells Revealed By Predictive Analytics and Xenotransplants

Javed K Manesia, PhD, Sakhar Almoflehi, Roya Pasha, Suria Jahan, MSc, John Blake, PhD, Julie Audet, PhD, Nicolas Pineault, PhD

Blood (2019) 134 (Supplement_1): 1185.

https://doi.org/10.1182/blood-2019-128692

Published: 2019

Journal Articles

Conditioned Medium Represents a Useful Solution to Increase the Expansion of Multipotent Progenitors with Strong Platelet Engraftment Activity

Ahmad Abu-Khader, PhD, Gwendoline Bugnot, MSc, Manal Alsheikh, BSc, Roya Pasha, MSc, Nicolas Pineault, PhD

Blood (2015) 126 (23): 4276.

https://doi.org/10.1182/blood.V126.23.4276.4276

Published: 2015

Journal Articles

Characterization of the Hematopoietic Supporting Activity of Osteoblasts Derived from Bone Marrow Mesenchymal Stromal Cells

Manal Alsheikh, BSc, Roya Pasha, Nicolas Pineault, PhD

Blood (2014) 124 (21): 4358.

https://doi.org/10.1182/blood.V124.21.4358.4358

Published: 2014

Journal Articles

Young maybe, but surely not immature

Nicolas Pineault

Blood (2011) 117 (15): 3940–3941.

https://doi.org/10.1182/blood-2011-02-337709

Published: 2011

Journal Articles

Characterization of the Impact of Culture on the Thrombopoietic Potential of Cord Blood Progenitors.

Lucie Boyer, MSc*, Hélène Émond, BSc, Nicolas Pineault, PhD

Blood (2010) 116 (21): 3710.

https://doi.org/10.1182/blood.V116.21.3710.3710

Published: 2010

Journal Articles

Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia

Cynthia L. Fisher, Nicolas Pineault, Christy Brookes, Cheryl D. Helgason, Hideaki Ohta, Caroline Bodner, Jay L. Hess, R. Keith Humphries, Hugh W. Brock

Blood (2010) 115 (1): 38–46.

https://doi.org/10.1182/blood-2009-07-230698

Published: 2010

Includes: Supplemental data

Journal Articles

Optimization of a Cytokine Cocktail for the Expansion of Cord Blood CD34+ Cells into Megakaryocytes Progenitors.

Lucie Boyer, MSc, Valerie Cortin, PhD, Amelie Robert, PhD, Nicolas Pineault, PhD

Blood (2007) 110 (11): 4041.

https://doi.org/10.1182/blood.V110.11.4041.4041

Published: 2007

Journal Articles

Optimization of a Cytokine Cocktail for the Expansion of Cord Blood (CB) CD34+ Cells into Megakaryocytes (MK) Progenitors towards the Ex Vivo Production of Platelets.

Valérie Cortin, PhD, Eng, Lucie Boyer, M.Sc, Alain Garnier, Ph.D., Eng., Nicolas Pineault, PhD

Blood (2006) 108 (11): 1673.

https://doi.org/10.1182/blood.V108.11.1673.1673

Published: 2006

Journal Articles

Identification of the Mechanisms Responsible for the Increased Megakaryopoiesis at 39°C.

Jean-Francois Boucher, BSc, Marie-Pierre Cayer, M.Sc., Lucie Boyer, M.Sc., Réal Lemieux, Ph.D., Chantal Proulx, Ph.D., Nicolas Pineault, Ph.D.

Blood (2006) 108 (11): 1128.

https://doi.org/10.1182/blood.V108.11.1128.1128

Published: 2006

Journal Articles

The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia

Lars Palmqvist, Bob Argiropoulos, Nicolas Pineault, Carolina Abramovich, Laura M. Sly, Gerald Krystal, Adrian Wan, R. Keith Humphries

Blood (2006) 108 (3): 1030–1036.

https://doi.org/10.1182/blood-2005-12-007005

Published: 2006

Journal Articles

The Leukemogenic Potential of the NUP98-PMX1 Fusion Protein Is Independent of the Known Binding Properties of PMX1 to the Serum Response Factor and the Serum Response Element and Requires the NUP98 Sequences.

Koichi Hirose, Nicolas Pineault, R. Keith Humphries

Blood (2004) 104 (11): 1968.

https://doi.org/10.1182/blood.V104.11.1968.1968

Published: 2004

Journal Articles

FLT3 Expression Is Increased by MEIS1 and Collaborates with NUP98-HOX Fusion Genes in the Induction of Acute Myeloid Leukemia.

Lars Palmqvist, MD, PhD, Nicolas Pineault, PhD, Bob Argiropoulos, PhD, Adrian Wan, Keith R. Humphries, MD, PhD

Blood (2004) 104 (11): 2552.

https://doi.org/10.1182/blood.V104.11.2552.2552

Published: 2004

Journal Articles

Redundant Leukemogenicity of NUP98-HOX Fusion Genes in Primary Murine Bone Marrow Cells Correlates with Gene Expression Changes Consistent with Common Key Target Genes.

Lars Palmqvist, MD, PhD, Nicolas Pineault, PhD, Patricia Rosten, Keith R. Humphries, MD, PhD

Blood (2004) 104 (11): 1134.

https://doi.org/10.1182/blood.V104.11.1134.1134

Published: 2004

Journal Articles

Multi-Log Clonal Ex-Vivo Expansion of Long Term Lympho-Myeloid Hematopoietic Stem Cells by Nup98-Hox Fusion Genes.

Hideaki Ohta, MD, Silvia Bakovic, Nicolas Pineault, PhD, Guy Sauvageau, PhD, R. Keith Humphries, PhD, MD

Blood (2004) 104 (11): 153.

https://doi.org/10.1182/blood.V104.11.153.153

Published: 2004

Journal Articles

Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1

Nicolas Pineault, Christian Buske, Michaela Feuring-Buske, Carolina Abramovich, Patty Rosten, Donna E. Hogge, Peter D. Aplan, R. Keith Humphries

Blood (2003) 101 (11): 4529–4538.

https://doi.org/10.1182/blood-2002-08-2484

Published: 2003

NARROW

Fat Mass Obesity-Associated (FTO) Driven Gene Regulatory Networks Control Hematopoietic Stem Cell Expansion and Homing

Loss of Autophagy Activity during Storage of Hematopoietic Stem Cell Grafts Is Associated with Reduced Potency

GAS6 Promotes Robust Expansion of Human Hematopoietic Stem and Progenitor Cells with High Serial Engraftment Activity

Stringent Small Molecule Dose Requirements for the Optimal Expansion of Hematopoietic Stem Cells Revealed By Predictive Analytics and Xenotransplants

Conditioned Medium Represents a Useful Solution to Increase the Expansion of Multipotent Progenitors with Strong Platelet Engraftment Activity

Characterization of the Hematopoietic Supporting Activity of Osteoblasts Derived from Bone Marrow Mesenchymal Stromal Cells

Young maybe, but surely not immature

Characterization of the Impact of Culture on the Thrombopoietic Potential of Cord Blood Progenitors.

Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia

Optimization of a Cytokine Cocktail for the Expansion of Cord Blood CD34+ Cells into Megakaryocytes Progenitors.

Optimization of a Cytokine Cocktail for the Expansion of Cord Blood (CB) CD34+ Cells into Megakaryocytes (MK) Progenitors towards the Ex Vivo Production of Platelets.

Identification of the Mechanisms Responsible for the Increased Megakaryopoiesis at 39°C.

The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia

The Leukemogenic Potential of the NUP98-PMX1 Fusion Protein Is Independent of the Known Binding Properties of PMX1 to the Serum Response Factor and the Serum Response Element and Requires the NUP98 Sequences.

FLT3 Expression Is Increased by MEIS1 and Collaborates with NUP98-HOX Fusion Genes in the Induction of Acute Myeloid Leukemia.

Redundant Leukemogenicity of NUP98-HOX Fusion Genes in Primary Murine Bone Marrow Cells Correlates with Gene Expression Changes Consistent with Common Key Target Genes.

Multi-Log Clonal Ex-Vivo Expansion of Long Term Lympho-Myeloid Hematopoietic Stem Cells by Nup98-Hox Fusion Genes.

Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1

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American Society of Hematology

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American Society of Hematology

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