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Journal Articles

Activated Natural Killer Cells Are Associated with Poor Clinical Prognosis in High-Risk B- and T- Cell Acute Lymphoblastic Leukemia

Caroline Duault, PharmD, PhD, Anil Kumar, PhD, Adeleh Taghi Khani, PhD, Sung June Lee, BA, Lu Yang, PhD, Min Huang, PhD, Christian Hurtz, PhD, Bryan Manning, BS, Lucy Ghoda, PhD, Tinisha McDonald, BS, Norman J. Lacayo, MD, Kathleen M. Sakamoto, MD PhD, Martin P. Carroll, MD, Guido Marcucci, MD, Jianhua Yu, PhD, Michael A. Caligiuri, MD, Holden T. Maecker, PhD, Srividya Swaminathan, PhD

Blood (2020) 136 (Supplement 1): 39.

https://doi.org/10.1182/blood-2020-140044

Published: 2020

Journal Articles

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-142270

Published: 2020

Journal Articles

Genetic Modulators of Niclosamide Sensitivity and Resistance in Acute Myeloid Leukemia

Anna Wojcicki, BS, Hee-Don Chae, PhD, Kyuho Han, PhD, Minyoung Youn, PhD, Mark C Wilkes, PhD, Norman J. Lacayo, MD, Michael Bassik, PhD, Kathleen M. Sakamoto, MD PhD

Blood (2020) 136 (Supplement 1): 29.

https://doi.org/10.1182/blood-2020-137340

Published: 2020

Journal Articles

Venetoclax and Navitoclax in Pediatric Patients with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Jeffrey E. Rubnitz, MD, Thomas B. Alexander, MDMPH, Theodore W. Laetsch, MD, Seong Lin Khaw, MD, Vinod A. Pullarkat, MD, Joseph T. Opferman, PhD, Kathryn G Roberts, PhD, Lindsey Rosenwinkel, Bo Tong, PhD, John C. Pesko, PhD, Mohamed Badawi, Deeksha Vishwamitra, PhD, Su Young Kim, Charles G Mullighan, MBBS, MD, Norman J. Lacayo, MD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-134582

Published: 2020

Journal Articles

A Novel Anti-Cancer Vaccine Approach for the Treatment of High-Risk Leukemia in Children

Thakur Satbir, PhD, Son Tran, Mohit Jain, PhD, Austin Lewis, Luis Murguia-Favela, MD, Faisal M Khan, PhD D (ABHI), Kevin J. Bielamowicz, MD, Olena Vaske, PhD, Victor A. Lewis, MD, Norman J. Lacayo, MD, Aru Narendran, MD PhD

Blood (2020) 136 (Supplement 1): 25.

https://doi.org/10.1182/blood-2020-143381

Published: 2020

Journal Articles

Safety and Efficacy of Venetoclax in Combination with Navitoclax in Adult and Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Blood (2019) 134 (Supplement_1): 285.

https://doi.org/10.1182/blood-2019-126977

Published: 2019

Journal Articles

Venetoclax in Combination with High-Dose Chemotherapy Is Active and Well-Tolerated in Children with Relapsed or Refractory Acute Myeloid Leukemia

Seth E Karol, MD, Thomas Alexander, MDMPH, Amit Budraja, PhD, Stanley Pounds, PhD, Kristin E Canavera, PhD, Lei Wang, MS, Joshua Wolf, MBBS, PhD, Jeffery M. Klco, MD PhD, Ahmed Hamed Salem, PhD FCP, Tammy Palenski, PhD, Norman J. Lacayo, MD, Ching-Hon Pui, MD, Joseph T. Opferman, PhD, Jeffrey Rubnitz, MD PhD

Blood (2019) 134 (Supplement_1): 178.

https://doi.org/10.1182/blood-2019-127716

Published: 2019

Journal Articles

Establishing a Novel in Vitro Informed Precision Clinical Trial Pathway for Refractory Pediatric Leukemia

Chunfen Zhang, MD, Ritul Sharma, MSc., Thakur Satbir, PhD, Allison Cheney, Olena Vaske, PhD, Lauren Sanders, Jessica Boklan, MD, Victor A. Lewis, MD, Ronald Anderson, MDFRCPC, Olga Kovalchuk, MD, PhD, Norman J. Lacayo, MD, Aru Narendran, MD PhD, Kevin J. Bielamowicz, MD

Blood (2019) 134 (Supplement_1): 2633.

https://doi.org/10.1182/blood-2019-131444

Published: 2019

Journal Articles

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Blood (2018) 132 (Supplement 1): 4246.

https://doi.org/10.1182/blood-2018-99-119974

Published: 2018

Journal Articles

Venetoclax and Navitoclax in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Thomas Alexander, MD MPH, Norman J. Lacayo, MD, Vinod A. Pullarkat, MD, Elias J. Jabbour, MD, Seong Lin Khaw, MD, Charles G. Mullighan, MBBS, MD, Ashish Bajel, MBBS, FRACP, FRCPA, Jessica Leonard, MD, Robin Norris, MD, Jeffrey Rubnitz, MD PhD, Susan I. Vear, MD MSCI, Michelle Schmidt, Bo Tong, PhD, Ying Zhou, PhD, Jeremy A. Ross, PhD, Lindsey Rosenwinkel, Amanda Jacobson, PhD, Su Young Kim, MD PhD, Wendy Stock, MD

Blood (2018) 132 (Supplement 1): 3966.

https://doi.org/10.1182/blood-2018-99-113464

Published: 2018

Journal Articles

Chromatin Remodeling Therapy and Capizzi Methotrexate in Treatment-Related MDS/AML

Catherine Aftandilian, MD, Kathleen M. Sakamoto, MD PhD, Kara L. Davis, DO, Gary Van Houten Dahl, MD, Norman J. Lacayo, MD

Blood (2018) 132 (Supplement 1): 5222.

https://doi.org/10.1182/blood-2018-99-110481

Published: 2018

Journal Articles

RSK Inhibition Induces Metaphase Arrest and Apoptosis in Acute Myeloid Leukemia Cells

Hee-Don Chae, PhD, Ritika Dutta, BS, Bruce Tiu, Kara L. Davis, DO, Norman J. Lacayo, MD, Kathleen M. Sakamoto, MD PhD

Blood (2017) 130 (Supplement 1): 2530.

https://doi.org/10.1182/blood.V130.Suppl_1.2530.2530

Published: 2017

Journal Articles

Improvement in Treatment Outcome and Identification of a New Prognostic Parameter in Down Syndrome Acute Myeloid Leukemia (DS-AML): Results of the Children’s Oncology Group (COG) Phase III AAML0431 Trial

Jeffrey W Taub, MD, Jason N Berman, MD, Johann K. Hitzler, MD, April D. Sorrell, MD, Norman J. Lacayo, MD, Kelley Mast, MD, David R. Head, MD, Susana C. Raimondi, PhD, Betsy A. Hirsch, PhD, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Dario Campana, MD PhD, Elaine Coustan-Smith, MS, Prasad Mathew, Alan S. Gamis, MD MPH

Blood (2014) 124 (21): 278.

https://doi.org/10.1182/blood.V124.21.278.278

Published: 2014

Journal Articles

Use Of Rearranged Immune Receptor Sequencing To Measure Minimal Residual Disease (MRD) In Bone Marrow, Cerebrospinal Fluid and Testes In Relapsed Childhood Acute Lymphoblastic Leukemia

Norman J. Lacayo, MD, Li Weng, PhD, Charles Gawad, MD, Malek Faham, MD, PhD, Gary V Dahl, MD

Blood (2013) 122 (21): 4984.

https://doi.org/10.1182/blood.V122.21.4984.4984

Published: 2013

Journal Articles

Comparison of High-Throughput Sequencing and Flow Cytometry for Measuring Minimal Residual Disease in Pediatric Acute Lymphoblastic Leukemia: A Children's Oncology Group Cohort

Charles Gawad, MD, Michael J. Borowitz, MD, PhD, Gary V. Dahl, MD, Meenakshi Devidas, PhD, Malek Faham, MD, PhD, Martin Moorhead, PhD, Brent L. Wood, MD, PhD, Jianbiao Zheng, PhD, Mignon L. Loh, MD, Norman J. Lacayo, MD

Blood (2012) 120 (21): 1440.

https://doi.org/10.1182/blood.V120.21.1440.1440

Published: 2012

Journal Articles

Single Cell Network Profiling (SCNP)-Based Classifier to Predict Response to Induction Therapy in Pediatric Patients with De Novo Acute Myeloid Leukemia (AML): Validation Study Results,

Norman J. Lacayo, MD, Todd A. Alonzo, PhD, Urte Gayko, Ph.D., Matt Westfall, Ph.D., Norman Purvis, Ph.D., Santosh Putta, Ph.D., James Hackett, Ph.D., Aileen Cleary Cohen, MD, PhD, Robert B. Gerbing, M.A., Gary V Dahl, MD, Alan S. Gamis, MD, MPH, Soheil Meshinchi, MD, Ph.D.

Blood (2011) 118 (21): 3544.

https://doi.org/10.1182/blood.V118.21.3544.3544

Published: 2011

Journal Articles

Next-Generation Sequencing of Immunoglobulin Heavy Chain Variable Region in Diagnostic Samples of Pediatric Acute Lymphoblastic Leukemia Identifies Hundreds of Clonal Subpopulations with Multiple Immunophenotypes

Charles Gawad, MD, Malek Faham, MD, PhD, Tom Willis, PhD, Martin Moorhead, PhD, Victoria Carlton, PhD, Jianbiao Zheng, PhD, Mark Klinger, Gary V Dahl, MD, Norman J. Lacayo, MD

Blood (2011) 118 (21): 1436.

https://doi.org/10.1182/blood.V118.21.1436.1436

Published: 2011

Journal Articles

Single Cell Network Profiling (SCNP) Signatures Predict Response to Induction Therapy and Relapse Risk In Pediatric Patients with Acute Myeloid Leukemia: Children's Oncology Group (COG) Study POG-9421

Norman J. Lacayo, MD, Aileen Cohen, Ph.D., M.D., Matt Westfall, Ph.D., Alan Lackey, MS, Xiaohua (Robert) Xin, Ph.D., M.D., Urte Gayko, Ph.D., Santosh Putta, Ph.D., Soheil Meshinchi, MD, PhD, Susana C. Raimondi, PhD, Todd A. Alonzo, PhD, Robert J. Arceci, MD, PhD, Yaddanapudi Ravindranath, MD, Gary Van Houten Dahl, MD, Alessandra Cesano, MD

Blood (2010) 116 (21): 954.

https://doi.org/10.1182/blood.V116.21.954.954

Published: 2010

Journal Articles

Sample Cryopreservation Does Not Affect Functional Read Outs In SCNP Assays: Implications for Biomarker Development

Alessandra Cesano, MD, Jason R Gotlib, MD, MS, Norman J. Lacayo, MD, Santosh Putta, Ph.D., Alan Lackey, MS, Urte Gayko, Ph.D., Steven M. Kornblau, MD

Blood (2010) 116 (21): 4843.

https://doi.org/10.1182/blood.V116.21.4843.4843

Published: 2010

Journal Articles

Acute Megakaryoblastic Leukemia (AMKL) in Children without Down Syndrome.

Maureen O'Brien, MD, Gary Dahl, MD, Stanley Pounds, Norman J. Lacayo, MD, Jeffrey Taub, MD, Myron Chang, Howard J. Weinstein, MD, Yaddanapudi Ravindranath, MBBS, Dario Campana, MD, PhD, Ching-Hon Pui, MD, Jeffrey Rubnitz, MD, PhD

Blood (2009) 114 (22): 482.

https://doi.org/10.1182/blood.V114.22.482.482

Published: 2009

NARROW

Activated Natural Killer Cells Are Associated with Poor Clinical Prognosis in High-Risk B- and T- Cell Acute Lymphoblastic Leukemia

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Genetic Modulators of Niclosamide Sensitivity and Resistance in Acute Myeloid Leukemia

Venetoclax and Navitoclax in Pediatric Patients with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

A Novel Anti-Cancer Vaccine Approach for the Treatment of High-Risk Leukemia in Children

Safety and Efficacy of Venetoclax in Combination with Navitoclax in Adult and Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Venetoclax in Combination with High-Dose Chemotherapy Is Active and Well-Tolerated in Children with Relapsed or Refractory Acute Myeloid Leukemia

Establishing a Novel in Vitro Informed Precision Clinical Trial Pathway for Refractory Pediatric Leukemia

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Venetoclax and Navitoclax in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Chromatin Remodeling Therapy and Capizzi Methotrexate in Treatment-Related MDS/AML

RSK Inhibition Induces Metaphase Arrest and Apoptosis in Acute Myeloid Leukemia Cells

Improvement in Treatment Outcome and Identification of a New Prognostic Parameter in Down Syndrome Acute Myeloid Leukemia (DS-AML): Results of the Children’s Oncology Group (COG) Phase III AAML0431 Trial

Use Of Rearranged Immune Receptor Sequencing To Measure Minimal Residual Disease (MRD) In Bone Marrow, Cerebrospinal Fluid and Testes In Relapsed Childhood Acute Lymphoblastic Leukemia

Comparison of High-Throughput Sequencing and Flow Cytometry for Measuring Minimal Residual Disease in Pediatric Acute Lymphoblastic Leukemia: A Children's Oncology Group Cohort

Single Cell Network Profiling (SCNP)-Based Classifier to Predict Response to Induction Therapy in Pediatric Patients with De Novo Acute Myeloid Leukemia (AML): Validation Study Results,

Next-Generation Sequencing of Immunoglobulin Heavy Chain Variable Region in Diagnostic Samples of Pediatric Acute Lymphoblastic Leukemia Identifies Hundreds of Clonal Subpopulations with Multiple Immunophenotypes

Single Cell Network Profiling (SCNP) Signatures Predict Response to Induction Therapy and Relapse Risk In Pediatric Patients with Acute Myeloid Leukemia: Children's Oncology Group (COG) Study POG-9421

Sample Cryopreservation Does Not Affect Functional Read Outs In SCNP Assays: Implications for Biomarker Development

Acute Megakaryoblastic Leukemia (AMKL) in Children without Down Syndrome.

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American Society of Hematology

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American Society of Hematology

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