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Journal Articles

Validation of the Bioequivalence of USP Potency Adjusted Porcine, Ovine, and Bovine Heparins

Nausheen Baig, Ahmed Kouta, Walter Jeske, PhD, Debra Hoppensteadt, PhD, Jeanine Walenga, PhD, Omer Iqbal, MD, Fakiha Siddiqui, Mamdouh Bakhos, MD, Jawed Fareed, PhD

Blood (2020) 136 (Supplement 1): 6.

https://doi.org/10.1182/blood-2020-142861

Published: 2020

Journal Articles

Potency Equated Porcine and Bovine Mucosal Heparin Are Bioequivalent in Terms of Biochemical and Pharmacological Effects

Nausheen Baig, Ahmed Kouta, Fakiha Siddiqui, Ambar Farooqui, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Cassie Bacher, Sharan Krishnappan, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 3665.

https://doi.org/10.1182/blood-2019-126075

Published: 2019

Journal Articles

Prothrombinase Induced Clotting Time Is More Sensitive then aPTT and PT and Can be Used for the Monitoring of Anti-Xa Agents in Whole Blood and Plasma

Debra Hoppensteadt, PhD, Emily Bontekoe, Fakiha Siddiqui, Ambar Farooqui, Omer Iqbal, MD, Walter Jeske, PhD, Jeanine Walenga, PhD, Alfonso J Tafur, MD MS, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 3374.

https://doi.org/10.1182/blood-2019-131221

Published: 2019

Journal Articles

Bovine Heparin Demonstrates the Same Interaction with HIT Antibodies As Porcine Heparin

Jeanine Walenga, PhD, Walter Jeske, PhD, Sabrina Bertini, Giulia Risi, Michelle Sung, BS, Ambar Farooqui, Cassie Bacher, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Bruce Lewis, Mamdouh Bakhos, MD

Blood (2019) 134 (Supplement_1): 2351.

https://doi.org/10.1182/blood-2019-127304

Published: 2019

Journal Articles

Comparative Studies on the Interaction of Unfractionated Heparin and Sulodexide with Functional Anti-Heparin Platelet Factor 4 Antibodies

Ambar Farooqui, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Cassie Bacher, Jeanine Walenga, PhD, Ahmed Kouta, Walter Jeske, PhD, Bruce Lewis, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 2446.

https://doi.org/10.1182/blood-2019-131825

Published: 2019

Journal Articles

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Ahmed Kouta, Walter Jeske, PhD, Rick Duff, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 165.

https://doi.org/10.1182/blood-2019-131943

Published: 2019

Journal Articles

Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban By Andexanet Alfa As Measured By Whole Blood Thromboelastographic Analysis

Siddharth Mehrotra, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Alfonso J Tafur, MD MS, Bruce Lewis, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 1155.

https://doi.org/10.1182/blood-2019-131907

Published: 2019

Journal Articles

Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum

Fakiha Siddiqui, Siddharth Mehrotra, Vishnu Venkitasubramony, Rithik Raina, Lorenzo Storino Ramacciotti, Jack Bontekoe, BS, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Jawed Fareed, PhD

Blood (2018) 132 (Supplement 1): 2520.

https://doi.org/10.1182/blood-2018-99-116993

Published: 2018

Journal Articles

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Michelle Sung, BS, Jeanine Walenga, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Mamdouh Bakhos, MD

Blood (2018) 132 (Supplement 1): 2540.

https://doi.org/10.1182/blood-2018-99-118781

Published: 2018

Journal Articles

Symptom Duration Is Positively Correlated with Factor XIIIa Activity in Acute Pulmonary Embolism

Yevgeniy Brailovsky, DO, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Kevin Simpson, Nathan Mcclane, Jawed Fareed, PhD, Amir Darki, MD MSc

Blood (2018) 132 (Supplement 1): 5047.

https://doi.org/10.1182/blood-2018-99-119733

Published: 2018

Journal Articles

Bovine Heparin Compared to Porcine Heparin to Demonstrate Bioequivalence

Marco Khiella, Walter Jeske, PhD, Jeanine Walenga, PhD, Omer Iqbal, MD, Rajan Laddu, Fakiha Siddiqui, Mamdouh Bakhos, MD

Blood (2018) 132 (Supplement 1): 1253.

https://doi.org/10.1182/blood-2018-99-118809

Published: 2018

Journal Articles

Comparative Studies on the Anticoagulant Actions of Recombinant Thrombomodulin and Heparin and Their Neutralization By FEIBA As Measured By Thromboelastography

Parul Aggarwal, Zafar Siddiqui, Omer Iqbal, MD, Walter Jeske, PhD, Debra Hoppensteadt, PhD, Kazuhisa Tsuruta, PhD, Jawed Fareed, PhD, Mary Lewis

Blood (2016) 128 (22): 2608.

https://doi.org/10.1182/blood.V128.22.2608.2608

Published: 2016

Journal Articles

Comparative Anticoagulant Effects of Recombinant Thrombomodulin, Antithrombin, and Unfractionated Heparin, Hematological Implications

Zafar Siddiqui, Parul Aggarwal, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Mary Lewis, Schuharazad Abro, MD, Kazuhisa Tsuruta, PhD, Jawed Fareed, PhD

Blood (2016) 128 (22): 4974.

https://doi.org/10.1182/blood.V128.22.4974.4974

Published: 2016

Journal Articles

Dabigatran Neutralizing Antobody, Idarucizumab, Exhibits Procoagulant and Platelet Activation Responses in Whole Blood. Potential Clinical Implications

Zafar Siddiqui, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Mary Lewis, Rohan Rege, Schuharazad Abro, MD, Jawed Fareed, PhD

Blood (2016) 128 (22): 2622.

https://doi.org/10.1182/blood.V128.22.2622.2622

Published: 2016

Journal Articles

Functional Protection of Platelets By Tri-Block Polymer (Poloxamer-188 ) As Studied in Agonist Induced Platelet Aggregation Systems

Nil Guler, MD, Schuharazad Abro, Martin Emanuele, PhD, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Jawed Fareed, PhD

Blood (2015) 126 (23): 1037.

https://doi.org/10.1182/blood.V126.23.1037.1037

Published: 2015

Journal Articles

Role of Platelet Activation in the Pathogenesis of Heart Failure in End-Stage Renal Disease Patients

Ryan McMillan, Vinod Bansal, Leonidas Skiadopoulos, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Ravipresenna Parasuraman, Nil Guler, MD, Jawed Fareed, PhD

Blood (2015) 126 (23): 4636.

https://doi.org/10.1182/blood.V126.23.4636.4636

Published: 2015

Journal Articles

Drug Interactions of Newer Oral Anticoagulants Dabigatran, Rivaroxaban, and Apixaban with Routinely Used Nonanticoagulant/Antiplatelet Drugs

Shermin Sayani, BS, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Jawed Fareed, PhD

Blood (2014) 124 (21): 4267.

https://doi.org/10.1182/blood.V124.21.4267.4267

Published: 2014

Journal Articles

Usefulness of Dilute Russell’s Viper Venom Clotting Time (DRVVT) for the Routine Monitoring of New Oral Anticoagulants

Debra Hoppensteadt, PhD, Jake Kola, Mark Brayne, Omer Iqbal, MD, Jawed Fareed, PhD

Blood (2014) 124 (21): 1537.

https://doi.org/10.1182/blood.V124.21.1537.1537

Published: 2014

Journal Articles

Circulating Levels of Rivaroxaban Provide Different Results in Different Clot Based and Amidolytic Assays. a Study on Patients Treated with Two Different Dosages of Rivaroxaban

Debra Hoppensteadt, PhD, Daneyal Syed, BS, Mateja Jezovnik, Pavel Poredos, Sermin Tetik, Omer Iqbal, MD, Jeanine M. Walenga, PhD, Jawed Fareed, PhD

Blood (2014) 124 (21): 5084.

https://doi.org/10.1182/blood.V124.21.5084.5084

Published: 2014

Journal Articles

Effect Of Purified Poloxamer 188 and Various Dextrans On Erythrocyte Sedimentation Rate In Healthy Subjects and Patients With Sickle Cell Disease

Debra Hoppensteadt, Ph.D., Martin Emanuele, PhD, Joann Molnar, BS, Omer Iqbal, MD, Jawed Fareed, Ph.D.

Blood (2013) 122 (21): 4764.

https://doi.org/10.1182/blood.V122.21.4764.4764

Published: 2013

NARROW

Validation of the Bioequivalence of USP Potency Adjusted Porcine, Ovine, and Bovine Heparins

Potency Equated Porcine and Bovine Mucosal Heparin Are Bioequivalent in Terms of Biochemical and Pharmacological Effects

Prothrombinase Induced Clotting Time Is More Sensitive then aPTT and PT and Can be Used for the Monitoring of Anti-Xa Agents in Whole Blood and Plasma

Bovine Heparin Demonstrates the Same Interaction with HIT Antibodies As Porcine Heparin

Comparative Studies on the Interaction of Unfractionated Heparin and Sulodexide with Functional Anti-Heparin Platelet Factor 4 Antibodies

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban By Andexanet Alfa As Measured By Whole Blood Thromboelastographic Analysis

Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Symptom Duration Is Positively Correlated with Factor XIIIa Activity in Acute Pulmonary Embolism

Bovine Heparin Compared to Porcine Heparin to Demonstrate Bioequivalence

Comparative Studies on the Anticoagulant Actions of Recombinant Thrombomodulin and Heparin and Their Neutralization By FEIBA As Measured By Thromboelastography

Comparative Anticoagulant Effects of Recombinant Thrombomodulin, Antithrombin, and Unfractionated Heparin, Hematological Implications

Dabigatran Neutralizing Antobody, Idarucizumab, Exhibits Procoagulant and Platelet Activation Responses in Whole Blood. Potential Clinical Implications

Functional Protection of Platelets By Tri-Block Polymer (Poloxamer-188 ) As Studied in Agonist Induced Platelet Aggregation Systems

Role of Platelet Activation in the Pathogenesis of Heart Failure in End-Stage Renal Disease Patients

Drug Interactions of Newer Oral Anticoagulants Dabigatran, Rivaroxaban, and Apixaban with Routinely Used Nonanticoagulant/Antiplatelet Drugs

Usefulness of Dilute Russell’s Viper Venom Clotting Time (DRVVT) for the Routine Monitoring of New Oral Anticoagulants

Circulating Levels of Rivaroxaban Provide Different Results in Different Clot Based and Amidolytic Assays. a Study on Patients Treated with Two Different Dosages of Rivaroxaban

Effect Of Purified Poloxamer 188 and Various Dextrans On Erythrocyte Sedimentation Rate In Healthy Subjects and Patients With Sickle Cell Disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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