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Osheiza Abdulmalik, DVM, MS
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Journal Articles

SCD-101: A New Anti-Sickling Drug Reduces Pain and Fatigue and Improves Red Blood Cell Shape in Peripheral Blood of Patients with Sickle Cell Disease

Robert Swift, PhD, Osheiza Abdulmalik, DVM, MS, Qiukan Chen, Toshio Asakura, MD PhD, Kelsey Gustafson, MS, James E Simon, PhD, Virdah Zaman, MS, Kevin Alexis Quiusky, MD, Kathryn L. Hassell, MD, Iuliana Shapira, MD, Gurinder Sidhu, MD, Tracian James-Goulbourne, MD, Kisha Carrington, MD, John Muthu, MD, Peter N Gillette, MD
Journal: Blood
Blood (2016) 128 (22): 121.
https://doi.org/10.1182/blood.V128.22.121.121
Published: 2016
Journal Articles

Adult Hemoglobin Production, Chain Rebalance, and Splice Correction in IVS2-745 Beta-Thalassemia Patient Cells Using 2'-O-Methoxyethyl Splice-Switching Oligos

Alisa Cheung Dong, Valentina Ghiaccio, Irene Motta, MD, Shuling Guo, PhD, Raechel Peralta, MS, Coralea Stephanou, PhD, Paola Delbini, PhD, Connie Chen, Soteroula Christou, Marina Kleanthous, PhD, Maria Domenica Cappellini, MD, Osheiza Abdulmalik, DVM, MS, Laura Breda, PhD, Stefano Rivella, PhD
Journal: Blood
Blood (2016) 128 (22): 1014.
https://doi.org/10.1182/blood.V128.22.1014.1014
Published: 2016
Journal Articles

Development of a Triazolyldisulfide Compound That Increases the Affinity of Hemoglobin for Oxygen and Reduces Hypoxic Sickling of Sickle Cells

Akito Nakagawa, PhD, Ferrari Michele, MD, Chen Liu, PhD, Lorenzo Berra, MD, Elizabeth S. Klings, MD, Martin K. Safo, PhD, Donald B. Bloch, MD, Osheiza Abdulmalik, DVM, MS, Warren M. Zapol, MD
Journal: Blood
Blood (2016) 128 (22): 3642.
https://doi.org/10.1182/blood.V128.22.3642.3642
Published: 2016
Journal Articles

Vzhe-039, a Novel Structurally-Enhanced Allosteric Hemoglobin Effector Inhibits Sickling of SS Erythrocytes In Vitro , and Exhibits Improved Pharmacologic Properties In Vivo

Martin K. Safo, PhD, Guoyan Xu, PhD, Mohini Ghatge, PhD, Qiukan Chen, Carla Casu, PhD, David Tanya, PhD, Yan Zhang, PhD, Jurgen Venitz, MD PhD, Osheiza Abdulmalik, DVM, MS
Journal: Blood
Blood (2016) 128 (22): 3645.
https://doi.org/10.1182/blood.V128.22.3645.3645
Published: 2016
Journal Articles

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

Kaiqi Sun, BS, Yang Xia, MD PhD, Angelo D'Alessandro, PhD, Mostafa H Ahmed, PhD, Yujin Zhang, MD, Anren Song, PhD, Tzu-Ping KO, Travis Nemkov, Julie Haines, Hongyu Wu, PhD, Morayo G. Adebiyi, BS, Hong Liu, MD, Aji Huang, BS, MS, Zhangzhe Peng, MD, Yuan Edward Wen, Alexander Wen, Vladimir Berka, PhD, Mikhail Bogdanov, PhD, Osheiza Abdulmalik, DVM, MS, Gregory J Kato, MD, Ah-lim Tsai, Modupe Idowu, MD, Harinder S. Juneja, MD, Rodney E. Kellems, PhD, Kirk C Hansen, PhD, Martin K. Safo, PhD
Journal: Blood
Blood (2016) 128 (22): 2474.
https://doi.org/10.1182/blood.V128.22.2474.2474
Published: 2016
Journal Articles

Temporally Distinct Developmental Waves of Erythropoiesis from Human Pluripotent Stem Cells

Orna Steinberg Shemer, MD MSc, Marta Byrska-Bishop, PhD, Jacob C Ulirsch, Osheiza Abdulmalik, DVM, MS, Yu Yao, MD, Ah Ram Kim, PhD, Paul Gadue, PhD, Paul D. Kingsley, PhD, Deborah French, PhD, Ross C. Hardison, PhD, James Palis, MD, Vijay G Sankaran, MD PhD, Mitchell J Weiss, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1170.
https://doi.org/10.1182/blood.V126.23.1170.1170
Published: 2015
Journal Articles

Novel Structurally-Modified Allosteric Effectors of Hemoglobin Exhibit Superior Antisickling Properties

Osheiza Abdulmalik, DVM, MS, Tanvi Deshpande, MS, Mohini Ghatge, PhD, Yan Zhang, PhD, Jurgen Venitz, MDPhD, Apurvasena Parikh, PhD, Martin K. Safo, PhD
Journal: Blood
Blood (2014) 124 (21): 218.
https://doi.org/10.1182/blood.V124.21.218.218
Published: 2014
Journal Articles

Methemoglobinemia In Rhesus Monkeys Due To M-Hemoglobinopathy

Osheiza Abdulmalik, DVM, MS, Larry Handt, DVM, MS, Martin Safo, PhD, Mary M Patterson, MS, DVM, Ping Wang, Caitlin A Fitzgerald, BS, Urs Giger, PD Dr. med. vet. MS FVH
Journal: Blood
Blood (2013) 122 (21): 4696.
https://doi.org/10.1182/blood.V122.21.4696.4696
Published: 2013
Journal Articles

Design and Validation of Genes Encoding Hyperstable β-Globin mRNAs.

Osheiza Abdulmalik, DVM, MS, J. Eric Russell, MD
Journal: Blood
Blood (2009) 114 (22): 4059.
https://doi.org/10.1182/blood.V114.22.4059.4059
Published: 2009