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Qiukan Chen
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Journal Articles

SCD-101: A New Anti-Sickling Drug Reduces Pain and Fatigue and Improves Red Blood Cell Shape in Peripheral Blood of Patients with Sickle Cell Disease

Robert Swift, PhD, Osheiza Abdulmalik, DVM, MS, Qiukan Chen, Toshio Asakura, MD PhD, Kelsey Gustafson, MS, James E Simon, PhD, Virdah Zaman, MS, Kevin Alexis Quiusky, MD, Kathryn L. Hassell, MD, Iuliana Shapira, MD, Gurinder Sidhu, MD, Tracian James-Goulbourne, MD, Kisha Carrington, MD, John Muthu, MD, Peter N Gillette, MD
Journal: Blood
Blood (2016) 128 (22): 121.
https://doi.org/10.1182/blood.V128.22.121.121
Published: 2016
Journal Articles

Vzhe-039, a Novel Structurally-Enhanced Allosteric Hemoglobin Effector Inhibits Sickling of SS Erythrocytes In Vitro , and Exhibits Improved Pharmacologic Properties In Vivo

Martin K. Safo, PhD, Guoyan Xu, PhD, Mohini Ghatge, PhD, Qiukan Chen, Carla Casu, PhD, David Tanya, PhD, Yan Zhang, PhD, Jurgen Venitz, MD PhD, Osheiza Abdulmalik, DVM, MS
Journal: Blood
Blood (2016) 128 (22): 3645.
https://doi.org/10.1182/blood.V128.22.3645.3645
Published: 2016
Journal Articles

Correction of murine hemoglobinopathies by prenatal tolerance induction and postnatal nonmyeloablative allogeneic BM transplants

William H. Peranteau, Satoshi Hayashi, Osheiza Abdulmalik, Qiukan Chen, Aziz Merchant, Toshio Asakura, Alan W. Flake
Journal: Blood
Blood (2015) 126 (10): 1245–1254.
https://doi.org/10.1182/blood-2015-03-636803
Published: 2015
Includes: Supplemental data
Journal Articles

New Approach for Finding Novel Antisickling Agents at the NIH NHLBI Sickle Cell Disease Reference Laboratory.

Toshio Asakura, MD, PhD, Jisheng Yang, Qiukan Chen, MD, Greg Evans, PhD, Osheiza Abdulmalik, DVM
Journal: Blood
Blood (2006) 108 (11): 1219.
https://doi.org/10.1182/blood.V108.11.1219.1219
Published: 2006
Journal Articles

Various Drugs with or without an Antisickling Effect in the In Vitro Tests Showed a Strong Antisickling Effect in the In Vivo Studies in Transgenic Sickle Mice.

Toshio Asakura, MD, PhD, Osheiza Abdulmalik, DVM, Efe Iyamu, PhD, Qiukan Chen, MD, Jisheng Yang, Donald J. Abraham, PhD, Martin K. Safo, PhD, Carlo Brugnara, MD, Greg Evans, PhD
Journal: Blood
Blood (2005) 106 (11): 3190.
https://doi.org/10.1182/blood.V106.11.3190.3190
Published: 2005
Journal Articles

In Vitro Antisickling Effects of Novel Pyridyl Derivatives with Enhanced Potency.

Osheiza Y. Abdulmalik, DVM, Martin K. Safo, PhD, Gajanan Joshi, PhD, Jisheng Yang, Qiukan Chen, Daniel Obeng, Donald J. Abraham, PhD, Toshio Asakura, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2347.
https://doi.org/10.1182/blood.V106.11.2347.2347
Published: 2005
Journal Articles

MSDD1, a Prodrug of 5-Hydroxymethyl-2-Furfural (5HMF), Prolongs the Antisickling Effect of 5HMF in Transgenic Sickle Mice.

Osheiza Abdulmalik, DVM, Martin K. Safo, PhD, Richmond Danso-Danquah, PhD, Jisheng Yang, Qiukan Chen, MD, Carlo Brugnara, MD, Donald J. Abraham, PhD, Toshio Asakura, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3576.
https://doi.org/10.1182/blood.V104.11.3576.3576
Published: 2004
Journal Articles

Finding of 8 New Therapeutic Agents by the Use of New High-Throughput Drug Screening Methods Established by the Nhlbi Sicke Cell Disease Reference Laboratory.

Toshio Asakura, MD, PhD, Osheiza Abdulmalik, DVM, Efe Iyamu, PhD, Qiukan Chen, MD, Jisheng Yang, Carlo Brugnara, MD, Greg Evans, PhD
Journal: Blood
Blood (2004) 104 (11): 3751.
https://doi.org/10.1182/blood.V104.11.3751.3751
Published: 2004