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Journal Articles

Transcriptomic Profiling of Circulating Tumor Cells (CTCs) in Multiple Myeloma (MM): A New Model to Understand Disease Dissemination

Blood (2018) 132 (Supplement 1): 245.

https://doi.org/10.1182/blood-2018-99-113331

Published: 2018

Journal Articles

Pre-Clinical Efficacy of the Anti-CD38 Monoclonal Antibody (mAb) Isatuximab in Acute Myeloid Leukemia (AML)

Tomas Jelinek, Aintzane Zabaleta, PhD, Cristina Perez, Daniel Ajona, PhD, Diego Alignani, PhD, Idoia Rodriguez, Sonia Garate, Sarai Sarvide, Marta Lasa, Patricia Maiso, PhD, Felipe Prosper, MDPhD, Roman Hajek, Jesus F. San Miguel, MD, Bruno Paiva, PhD

Blood (2017) 130 (Supplement 1): 2655.

https://doi.org/10.1182/blood.V130.Suppl_1.2655.2655

Published: 2017

Journal Articles

High-Throughput Characterization and New Insight into the Role of Tumor Associated Macrophages (TAMs) in Multiple Myeloma (MM)

Paula Arana, Aintzane Zabaleta, Marta Lasa, Patricia Maiso, PhD, Diego Alignani, Tomas Jelinek, MD, Victor Segura, PhD, Wouter van den Bossche, Cristina Teodosio, Daniela Damasceno, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, Joan Bladé, Jacques J.M. van Dongen, MD PhD, Jesus San Miguel, MD PhD, Alberto Orfao, MD PhD, Bruno Paiva, PhD

Blood (2016) 128 (22): 482.

https://doi.org/10.1182/blood.V128.22.482.482

Published: 2016

Journal Articles

New Insights into the Mechanism of Action (MoA) of First-in-Class IgG-Based Bcma T-Cell Bispecific Antibody (TCB) for the Treatment of Multiple Myeloma (MM)

Laura Moreno, Aintzane Zabaleta, Diego Alignani, Marta Lasa, Patricia Maiso, PhD, Tomas Jelinek, MD, Victor Segura, PhD, Jose Antonio Delgado, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Klaus Strein, MD PhD, Minh Diem Vu, PhD, Jesus San Miguel, MD PhD, Bruno Paiva, PhD

Blood (2016) 128 (22): 2096.

https://doi.org/10.1182/blood.V128.22.2096.2096

Published: 2016

Journal Articles

Critical Analysis on the Mechanism of Action (MoA) of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma (MM)

Laura Moreno, Aintzane Zabaleta, Diego Alignani, Daniel Ajona, Marta Lasa, Patricia Maiso, PhD, Tomas Jelinek, MD, Victor Segura, PhD, Jose Antonio Delgado, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Jesus San Miguel, MD PhD, Bruno Paiva, PhD

Blood (2016) 128 (22): 2105.

https://doi.org/10.1182/blood.V128.22.2105.2105

Published: 2016

Journal Articles

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression in Multiple Myeloma (MM) and Represents a Novel Target for Therapy in MM

Yu Zhang, MD, Yong Zhang, PhD, Yuji Mishima, PhD, Michele Moschetta, MD, Wenjing Zhang, MD, Patricia Maiso, PhD, Antonio Sacco, BS, Yosra Aljawai, MS, Ilyas Sahin, MD, Michaela R. Reagan, PhD, Jennifer E. Ring, Winnie F. Tam, PhD, Qunli Xu, PhD, Jonathan A. Pachter, PhD, Aldo M Roccaro, MD PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 2101.

https://doi.org/10.1182/blood.V124.21.2101.2101

Published: 2014

Journal Articles

Novel CXCR4-Targeted Therapy to Inhibit Multiple Myeloma Bone Dissemination

Aldo M Roccaro, MD PhD, Antonio Sacco, BS, Michele Moschetta, MD, Yuji Mishima, PhD, Patricia Maiso, PhD, Daisy Huynh, MPS, Marco Chiarini, MSc, Pina M. Cardarelli, PhD, Lewis Cohen, MD MS, Michelle Kuhne, PhD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 4709.

https://doi.org/10.1182/blood.V124.21.4709.4709

Published: 2014

Journal Articles

Class I PI3K Isoforms Exert a Differential Role On Survival and Cell Trafficking In Multiple Myeloma

Ilyas Sahin, MD, Feda Azab, Michele Moschetta, MD, Yuji Mishima, PhD, Brian Tsang, Patricia Maiso, PhD, Antonio Sacco, BS, Aldo M Roccaro, MD, PhD, Abdel Kareem Azab, PhD, BSPharm, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3159.

https://doi.org/10.1182/blood.V122.21.3159.3159

Published: 2013

Journal Articles

Mirna Expression Profiling and Proteomic Analysis Of Circulating Exosomes From Multiple Myeloma Patients

Salomon Manier, MD, Erica N Boswell, BS, Siobhan Glavey, MD, Antonio Sacco, BS, Patricia Maiso, PhD, Yuji Mishima, PhD, Yosra Aljaway, BS, Ranjit Banwait, MA, Wenjing Zhang, MD, Yu Zhang, MD, Ilyas Sahin, MD, Michele Moschetta, MD, Yong Zhang, PhD, Michaela R Reagan, PhD, John M. Asara, PhD, Xavier Leleu, MD, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3086.

https://doi.org/10.1182/blood.V122.21.3086.3086

Published: 2013

Journal Articles

Microrna-Dependent Modulation Of Osteogenesis In a 3D In Vitro Bone Marrow Model System Of Multiple Myeloma

Michaela R Reagan, PhD, Yuji Mishima, PhD, Yong Zhang, PhD, Patricia Maiso, PhD, Salomon Manier, MD, Yu-Tzu Tai, PhD, Priya Dhir, Zhi Ning Lu, Masoumeh Memarzadeh, Antonio Sacco, BS, Yosra Aljawai, MS, Susanna Santos, PA-C, John Ready, MD, David L. Kaplan, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3093.

https://doi.org/10.1182/blood.V122.21.3093.3093

Published: 2013

Journal Articles

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression In Multiple Myeloma Through Modulation Of Wnt/β-Catenin Signaling Pathway

Yu Zhang, MD, Yong Zhang, PhD, Yuji Mishima, PhD, Michele Moschetta, MD, Wenjing Zhang, MD, Patricia Maiso, PhD, Antonio Sacco, BS, Yosra Aljawai, MS, Ilyas Sahin, MD, Michaela Reagan, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3094.

https://doi.org/10.1182/blood.V122.21.3094.3094

Published: 2013

Journal Articles

A Novel Activating Mutation Of CXCR4 Plays a Crucial Role In Waldenstrom Macroglobulinemia Biology

Aldo M Roccaro, MD, PhD, Antonio Sacco, BS, Cristina Jimenez, Patricia Maiso, PhD, Michele Moschetta, MD, Yuji Mishima, PhD, Michelle R. Kuhne, PhD, Pina M. Cardarelli, Ph.D., San Miguel Jesus F, MD PhD, Ramon Garcia-Sanz, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 272.

https://doi.org/10.1182/blood.V122.21.272.272

Published: 2013

Journal Articles

Lin28B/Let-7 Axis Regulates Multiple Myeloma Proliferation By Enhancing c-Myc and Ras Survival Pathways

Salomon Manier, MD, John T Powers, PhD, Antonio Sacco, BS, Michaela R Reagan, PhD, Michele Moschetta, MD, Siobhan Glavey, MD, Patricia Maiso, PhD, Ilyas Sahin, MD, Yuji Mishima, PhD, Yosra Aljaway, BS, Xavier Leleu, MD, PhD, Aldo M Roccaro, MD, PhD, George Q. Daley, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 273.

https://doi.org/10.1182/blood.V122.21.273.273

Published: 2013

Journal Articles

Metabolomic Profiling Identifies Mechanisms Regulating Hypoxia-Induced Drug Resistance In Multiple Myeloma

Patricia Maiso, PhD, Daisy Huynh, MPS, Yosra Aljawai, MS, John M. Asara, PhD, Antonio Sacco, BS, Michele Moschetta, MD, Yuji Mishima, PhD, Aldo M Roccaro, MD, PhD, Alec Kimmelman, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 121.

https://doi.org/10.1182/blood.V122.21.121.121

Published: 2013

Journal Articles

Bone Marrow Mobilization Of Endothelial Progenitor Cells Represents An Early Pathogenic Event During Multiple Myeloma Progression

Michele Moschetta, MD, Yuji Mishima, PhD, Yosra Aljawai, MS, Ilyas Sahin, MD, Arianna Calcinotto, PhD, Salomon Manier, MD, Patricia Maiso, PhD, Antonio Sacco, BS, Matteo Bellone, MD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 680.

https://doi.org/10.1182/blood.V122.21.680.680

Published: 2013

Journal Articles

Multiple Myeloma-Derived Bone-Marrow Mesenchymal Stem Cells: Microrna-, Gene Expression-Profiling and Functional Characterization

Michaela R Reagan, PhD, Aldo M Roccaro, MD, PhD, AbdelKareem Azab, PhD, Yong Zhang, PhD, Grace B O'Callaghan, PhD, Patricia Maiso, PhD, Salomon Manier, MD, David L. Kaplan, PhD, Irene M. Ghobrial, MD

Blood (2012) 120 (21): 1837.

https://doi.org/10.1182/blood.V120.21.1837.1837

Published: 2012

Journal Articles

Comparative miRNA Expression Profiling of Circulating Exosomes From MGUS and Smoldering Multiple Myeloma Patients

Salomon Manier, MD, Erica N Boswell, BS, Antonio Sacco, BS, Patricia Maiso, PhD, Ranjit Banwait, MA, Yosra Aljawai, BS, Xavier Leleu, MD, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2012) 120 (21): 3975.

https://doi.org/10.1182/blood.V120.21.3975.3975

Published: 2012

Journal Articles

Metabolomic Profiling Identifies Mechanisms Regulating Hypoxia-Induced Drug Resistance in Multiple Myeloma

Patricia Maiso, PhD, Yosra Aljawai, BS, Antonio Sacco, BS, Susanne B Breitkopf, PhD, Ilyas Sahin, MD, Salomon Manier, MD, Yang Liu, PhD, John M Asara, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2012) 120 (21): 3944.

https://doi.org/10.1182/blood.V120.21.3944.3944

Published: 2012

Journal Articles

CXCR4 Monoclonal Antibody, BMS-936564 (MDX-1338), Modulates Epithelial to Mesenchymal Transition (EMT) in Multiple Myeloma Cells

Aldo M Roccaro, MD, PhD, Antonio Sacco, BS, Michelle R. Kuhne, PhD, Abdel Kareem Azab, PhD, BSPharm, Patricia Maiso, PhD, Feda Azab, BPharm, Salomon Manier, MD, Yosra Aljaway, BS, Michaela R Reagan, PhD, Lewis Cohen, MD, MS, Pina M Cardarelli, Ph.D., Irene M. Ghobrial, MD

Blood (2012) 120 (21): 4009.

https://doi.org/10.1182/blood.V120.21.4009.4009

Published: 2012

Journal Articles

In Vivo Targeting of Stromal-Derived Factor-1 As a Strategy to Prevent Myeloma Cell Dissemination to Distant Bone Marrow Niches

Aldo M. Roccaro, MD, PhD, Antonio Sacco, BS, Marco Ungari, MD, Patricia Maiso, PhD, Salomon Manier, MD, Phong Quang, BS, Yosra Aljaway, BS, Dirk Zboralski, PhD, Anna Kruschinski, PhD, Fabio Facchetti, MD, Giuseppe Rossi, MD, Irene M. Ghobrial, MD

Blood (2012) 120 (21): 440.

https://doi.org/10.1182/blood.V120.21.440.440

Published: 2012

NARROW

Transcriptomic Profiling of Circulating Tumor Cells (CTCs) in Multiple Myeloma (MM): A New Model to Understand Disease Dissemination

Pre-Clinical Efficacy of the Anti-CD38 Monoclonal Antibody (mAb) Isatuximab in Acute Myeloid Leukemia (AML)

High-Throughput Characterization and New Insight into the Role of Tumor Associated Macrophages (TAMs) in Multiple Myeloma (MM)

New Insights into the Mechanism of Action (MoA) of First-in-Class IgG-Based Bcma T-Cell Bispecific Antibody (TCB) for the Treatment of Multiple Myeloma (MM)

Critical Analysis on the Mechanism of Action (MoA) of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma (MM)

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression in Multiple Myeloma (MM) and Represents a Novel Target for Therapy in MM

Novel CXCR4-Targeted Therapy to Inhibit Multiple Myeloma Bone Dissemination

Class I PI3K Isoforms Exert a Differential Role On Survival and Cell Trafficking In Multiple Myeloma

Mirna Expression Profiling and Proteomic Analysis Of Circulating Exosomes From Multiple Myeloma Patients

Microrna-Dependent Modulation Of Osteogenesis In a 3D In Vitro Bone Marrow Model System Of Multiple Myeloma

Proline-Rich Tyrosine Kinase (Pyk2) Promotes Tumor Progression In Multiple Myeloma Through Modulation Of Wnt/β-Catenin Signaling Pathway

A Novel Activating Mutation Of CXCR4 Plays a Crucial Role In Waldenstrom Macroglobulinemia Biology

Lin28B/Let-7 Axis Regulates Multiple Myeloma Proliferation By Enhancing c-Myc and Ras Survival Pathways

Metabolomic Profiling Identifies Mechanisms Regulating Hypoxia-Induced Drug Resistance In Multiple Myeloma

Bone Marrow Mobilization Of Endothelial Progenitor Cells Represents An Early Pathogenic Event During Multiple Myeloma Progression

Multiple Myeloma-Derived Bone-Marrow Mesenchymal Stem Cells: Microrna-, Gene Expression-Profiling and Functional Characterization

Comparative miRNA Expression Profiling of Circulating Exosomes From MGUS and Smoldering Multiple Myeloma Patients

Metabolomic Profiling Identifies Mechanisms Regulating Hypoxia-Induced Drug Resistance in Multiple Myeloma

CXCR4 Monoclonal Antibody, BMS-936564 (MDX-1338), Modulates Epithelial to Mesenchymal Transition (EMT) in Multiple Myeloma Cells

In Vivo Targeting of Stromal-Derived Factor-1 As a Strategy to Prevent Myeloma Cell Dissemination to Distant Bone Marrow Niches

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American Society of Hematology

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American Society of Hematology

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