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Patrick C. Falahee
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Journal Articles

Mgta-145, in Combination with Plerixafor in a Phase 1 Clinical Trial, Mobilizes Large Numbers of Human Hematopoietic Stem Cells and a Graft with Immunosuppressive Effects for Allogeneic Transplant

Kevin A. Goncalves, PhD, Sharon L. Hyzy, MS, Katelyn J. Hammond, BS, Patrick C. Falahee, PhD, Haley Howell, BS, BA, Jan Pinkas, PhD, Veit Schmelmer, PhD, Jonathan G. Hoggatt, PhD, David T. Scadden, MD, Steven M Devine, MD, John F. DiPersio, MD PhD, Will J. Savage, MDPhD, John C. Davis, Jr., MD MPH, MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-142804
Published: 2020
Journal Articles

Rapid and Robust Mobilization of CD34+ HSCs without G-CSF Following Administration of Mgta-145 Alone or in Combination with Plerixafor

John F. DiPersio, MD PhD, Jonathan Hoggatt, PhD, Steven Devine, MD, Lukasz Biernat, MD, Haley Howell, BS, BA, Veit Schmelmer, PhD, Jason R. Neale, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD, Kevin A. Goncalves, PhD, Glen D. Raffel, MD PhD, Patrick C. Falahee, PhD, Dwight M. Morrow, PhD, John C. Davis, Jr., MD MPH, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 1961.
https://doi.org/10.1182/blood-2019-127523
Published: 2019
Journal Articles

Targeting CD45 with an Amanitin Antibody-Drug Conjugate Effectively Depletes Human HSCs and Immune Cells for Transplant Conditioning

Rahul Palchaudhuri, PhD, Bradley R Pearse, PhD, Jennifer L Proctor, BS, Sharon L. Hyzy, MS, Sharon Aslanian, MS, Sean M McDonough, MS, Ganapathy Sarma, PhD, Melissa L. Brooks, BS, Anjali Bhat, MS, Danielle Ladwig, MS, Molly A McShea, MS, Nathan M Kallen, BA, Qing Li, PhD, Rajiv Panwar, PhD, Junia Dushime, BS, Pranoti Sawant, MS, Hillary L Adams, MS, Patrick C. Falahee, PhD, Tahirih L Lamothe, Andrew D Gabros, Lena Kien, BS, Geoff Gillard, PhD, Charlotte F McDonagh, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4526.
https://doi.org/10.1182/blood-2018-99-117167
Published: 2018
Journal Articles

MGTA-145 in Combination with Plerixafor Rapidly Mobilizes High Numbers of Hematopoietic Stem Cells and Graft-Versus-Host Disease Inhibiting Myeloid-Derived Suppressor Cells in Non-Human Primates

Kevin A. Goncalves, PhD, Patrick C. Falahee, PhD, Sharon L. Hyzy, MS, Shuping Li, PhD, Anthony E. Boitano, PhD, Dwight M. Morrow, PhD, Michael P. Cooke, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 116.
https://doi.org/10.1182/blood-2018-99-117370
Published: 2018
Journal Articles

The Combination of GROβ and AMD3100 Leads to Rapid and Robust Mobilization of Hematopoietic Stem Cells in Nonhuman Primates

Patrick C. Falahee, PhD, Kevin A. Goncalves, PhD, Sharon L. Hyzy, MS, Jennifer L. Proctor, BS, Jonathan Hoggatt, PhD, Dwight Morrow, PhD, Michael P. Cooke, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1920.
https://doi.org/10.1182/blood.V130.Suppl_1.1920.1920
Published: 2017
Journal Articles

Hematopoietic Stem and Progenitor Cells Locally Produce Neutrophils Necessary To Resolve S. Aureus -Infected Wounds

Patrick C Falahee, M.S., Jennifer L Granick, DVM PhD, Delsheen Dahmubed, Scott I Simon, PhD
Journal: Blood
Blood (2013) 122 (21): 4710.
https://doi.org/10.1182/blood.V122.21.4710.4710
Published: 2013
Journal Articles

Staphylococcus aureus recognition by hematopoietic stem and progenitor cells via TLR2/MyD88/PGE 2 stimulates granulopoiesis in wounds

Jennifer L. Granick, Patrick C. Falahee, Delsheen Dahmubed, Dori L. Borjesson, Lloyd S. Miller, Scott I. Simon
Journal: Blood
Blood (2013) 122 (10): 1770–1778.
https://doi.org/10.1182/blood-2012-11-466268
Published: 2013
Includes: Supplemental data