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Paul Stupple, PhD
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Journal Articles

PRMT5 Inhibition Selectively Targets Acute Myeloid Leukemia Stem Cells Though a p53-Dependent Mechanism

Emma Toulmin, PhD, Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Andrej Terzic, BSc, Feng Yan, BSc, Nicholas Wong, PhD, Ian Street, PhD, Paul Stupple, PhD, Stephen Jane, MD PhD, Andrew H Wei, MBBS, PhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4061.
https://doi.org/10.1182/blood-2018-99-117835
Published: 2018
Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 53.
https://doi.org/10.1182/blood-2018-99-118406
Published: 2018
Journal Articles

Selective Inhibitors of Arginine Methyl Transferase 5 (PRMT5) As a Novel Treatment for β-Thalassemia and Sickle Cell Disease.

Ian Street, PhD, Brendon Monahan, PhD, Hendrik Falk, PhD, Elizabeth Allan, PhD, Ylva Bergman, PhD, Paul Stupple, PhD, Ian Holmes, PhD, Alison Gregg, PhD, Susan Charman, PhD, Kurt Lackovic, PhD, Tom Peat, PhD, Scott Walker, PhD, Kym Lowes, PhD, Wilco Kersten, Jo Alcindor, PhD, Matthew Chung, Michael Parker, PhD, Richard Foitzik, PhD, Michelle Camerino, PhD, Marcia Nikac, PhD, Julian Grusovin, Pat Pilling, Stefan Sonderegger, PhD, Yuen Tan, PhD, Quan Zhao, David J. Curtis, M.D., Ph.D., Stephen M Jane, FRACP, FRCPA, MBBS, PhD
Journal: Blood
Blood (2012) 120 (21): 2129.
https://doi.org/10.1182/blood.V120.21.2129.2129
Published: 2012