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Journal Articles

The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis

Wenman Wu, Hongbo Li, Duraiswamy Navaneetham, Zachary W. Reichenbach, Ronald F. Tuma, Peter N. Walsh

Blood (2012) 120 (3): 671–677.

https://doi.org/10.1182/blood-2012-03-419523

Published: 2012

Journal Articles

Conformational Changes Facilitate FXI Autoactivation to FXIa

Wenman Wu, MD, PhD, Heinrich Roder, PhD, Peter N. Walsh, MD, PhD

Blood (2010) 116 (21): 19.

https://doi.org/10.1182/blood.V116.21.19.19

Published: 2010

Journal Articles

Structural and Mutational Analysis of Canonical Loop Residues In Protease Nexin 2 Involved In Factor XIa and Trypsin Inhibition.

Duraiswamy Navaneetham, Dipali Sinha, Peter N. Walsh, MD, PhD

Blood (2010) 116 (21): 1147.

https://doi.org/10.1182/blood.V116.21.1147.1147

Published: 2010

Journal Articles

Localization of Ligand-Binding Exosites In the Catalytic Domain of Factor XIa.

Ya-Chi Su, Dipali Sinha, Peter N. Walsh, MD, PhD

Blood (2010) 116 (21): 1148.

https://doi.org/10.1182/blood.V116.21.1148.1148

Published: 2010

Journal Articles

Platelets: yin and yang

Peter N. Walsh

Blood (2010) 115 (1): 1–2.

https://doi.org/10.1182/blood-2009-10-251272

Published: 2010

Journal Articles

Factor XI contributes to thrombin generation in the absence of factor XII

Dmitri V. Kravtsov, Anton Matafonov, Erik I. Tucker, Mao-fu Sun, Peter N. Walsh, Andras Gruber, David Gailani

Blood (2009) 114 (2): 452–458.

https://doi.org/10.1182/blood-2009-02-203604

Published: 2009

Journal Articles

The Role of the P1 Residue of Protease Nexin 2 and Basic Pancreatic Trypsin Inhibitor in the Mechanism of Factor XIa Inhibition.

Duraiswamy Navaneetham, Ph.D., Dipali Sinha, PhD, Peter N. Walsh, MD, PhD

Blood (2008) 112 (11): 2015.

https://doi.org/10.1182/blood.V112.11.2015.2015

Published: 2008

Journal Articles

Structural Determinants for Heparin Binding in Human Coagulation Factor XI.

Sergei Shikov, MS, Wenman Wu, MD, PhD, Peter N. Walsh, MD, PhD

Blood (2007) 110 (11): 2705.

https://doi.org/10.1182/blood.V110.11.2705.2705

Published: 2007

Journal Articles

Factor XI Homodimer Formation Is Mediated by Electrostatic (Lys331 with Glu287) and Hydrophobic (Ile290 with Leu284 and Tyr329 with Tyr329) Interactions in the Apple 4 Domain and Is Essential for Normal Proteolytic Activation of Factor XI by Factor XIIa, Thrombin and Factor XIa.

Wenman Wu, MD, PhD, Dipali Sinha, PhD, James D. Lear, PhD, Paul C. Billings, PhD, Peter N. Walsh, MD, PhD

Blood (2007) 110 (11): 2706.

https://doi.org/10.1182/blood.V110.11.2706.2706

Published: 2007

Journal Articles

The Role of Lipid Rafts in the Assembly and Down-Regulation of the Factor X Activating Complex on the Activated Platelet Membrane.

Syed S. Ahmad, MD, PhD, Ya-Chi Su, Peter N. Walsh, MD, PhD

Blood (2005) 106 (11): 1010.

https://doi.org/10.1182/blood.V106.11.1010.1010

Published: 2005

Journal Articles

NMR Structural Analysis and Folding Studies of the Factor XI Apple 4 Domain as a Model for Factor XI Homodimerization.

Paul W. Riley, Dharmaraj Samuel, PhD, Hong Cheng, PhD, Heinrich Roder, PhD, Peter N. Walsh, MD, PhD

Blood (2005) 106 (11): 1958.

https://doi.org/10.1182/blood.V106.11.1958.1958

Published: 2005

Journal Articles

Factor IX Substrate Binding Exosite on the Light Chain of Factor Xia.

Dipali Sinha, PhD, Mariola Marcinkiewicz, Duraiswamy Navaneetham, PhD, Peter N. Walsh, MD, PhD

Blood (2005) 106 (11): 1959.

https://doi.org/10.1182/blood.V106.11.1959.1959

Published: 2005

Journal Articles

The Factor XI Receptor on Collagen Activated Platelets Is gC1qR/P33.

Frank A. Baglia, PhD, Harlan R. Bradford, Robert W. Colman, MD, Ellinor I.B. Peerschke, PhD, Berhane Ghebrehiwet, PhD, Peter N. Walsh, MD, PhD

Blood (2005) 106 (11): 690.

https://doi.org/10.1182/blood.V106.11.690.690

Published: 2005

Journal Articles

Lipid Raft Association of a Shared Factor X/Prothrombin Binding Site on Human Platelets Is Mediated by the Gla Domain.

Syed S. Ahmad, M.D., Ph.D., Peter N. Walsh, M.D., Ph.D.

Blood (2004) 104 (11): 222.

https://doi.org/10.1182/blood.V104.11.222.222

Published: 2004

Journal Articles

NMR Structural Analysis of Factor XI Apple 4 Domain.

Dharmaraj Samuel, Ph.D., Hong Cheng, Ph.D., Paul W. Riley, Peter N. Walsh, M.D., Ph.D., Heinrich Roder, Ph.D.

Blood (2004) 104 (11): 1735.

https://doi.org/10.1182/blood.V104.11.1735.1735

Published: 2004

Journal Articles

Defective binding of factor XI–N248 to activated human platelets

Mao-Fu Sun, Frank A. Baglia, David Ho, Danko Martincic, Russell E. Ware, Peter N. Walsh, David Gailani

Blood (2001) 98 (1): 125–129.

https://doi.org/10.1182/blood.V98.1.125

Published: 2001

Journal Articles

Model for a factor IX activation complex on blood platelets: dimeric conformation of factor XIa is essential

David Gailani, David Ho, Mao-Fu Sun, Qiufang Cheng, Peter N. Walsh

Blood (2001) 97 (10): 3117–3122.

https://doi.org/10.1182/blood.V97.10.3117

Published: 2001

Journal Articles

Tissue-Specific Expression of Functional Platelet Factor XI Is Independent of Plasma Factor XI Expression

Chang-jun Hu, Frank A. Baglia, David C.B. Mills, Barbara A. Konkle, Peter N. Walsh

Blood (1998) 91 (10): 3800–3807.

https://doi.org/10.1182/blood.V91.10.3800

Published: 1998

Journal Articles

Platelet Antiheparin Activity: Storage Site and Release Mechanism

Peter N. Walsh, Dr., Giovanna Gagnatelli

Blood (1974) 44 (2): 157–168.

https://doi.org/10.1182/blood.V44.2.157.157

Published: 1974

Journal Articles

Platelet Coagulant Activities and Hemostasis: A Hypothesis

Peter N. Walsh, M.D.

Blood (1974) 43 (4): 597–605.

https://doi.org/10.1182/blood.V43.4.597.597

Published: 1974

NARROW

The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis

Conformational Changes Facilitate FXI Autoactivation to FXIa

Structural and Mutational Analysis of Canonical Loop Residues In Protease Nexin 2 Involved In Factor XIa and Trypsin Inhibition.

Localization of Ligand-Binding Exosites In the Catalytic Domain of Factor XIa.

Platelets: yin and yang

Factor XI contributes to thrombin generation in the absence of factor XII

The Role of the P1 Residue of Protease Nexin 2 and Basic Pancreatic Trypsin Inhibitor in the Mechanism of Factor XIa Inhibition.

Structural Determinants for Heparin Binding in Human Coagulation Factor XI.

Factor XI Homodimer Formation Is Mediated by Electrostatic (Lys331 with Glu287) and Hydrophobic (Ile290 with Leu284 and Tyr329 with Tyr329) Interactions in the Apple 4 Domain and Is Essential for Normal Proteolytic Activation of Factor XI by Factor XIIa, Thrombin and Factor XIa.

The Role of Lipid Rafts in the Assembly and Down-Regulation of the Factor X Activating Complex on the Activated Platelet Membrane.

NMR Structural Analysis and Folding Studies of the Factor XI Apple 4 Domain as a Model for Factor XI Homodimerization.

Factor IX Substrate Binding Exosite on the Light Chain of Factor Xia.

The Factor XI Receptor on Collagen Activated Platelets Is gC1qR/P33.

Lipid Raft Association of a Shared Factor X/Prothrombin Binding Site on Human Platelets Is Mediated by the Gla Domain.

NMR Structural Analysis of Factor XI Apple 4 Domain.

Defective binding of factor XI–N248 to activated human platelets

Model for a factor IX activation complex on blood platelets: dimeric conformation of factor XIa is essential

Tissue-Specific Expression of Functional Platelet Factor XI Is Independent of Plasma Factor XI Expression

Platelet Antiheparin Activity: Storage Site and Release Mechanism

Platelet Coagulant Activities and Hemostasis: A Hypothesis

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American Society of Hematology

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American Society of Hematology

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