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Priscila Santos Scheucher, PhD
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Journal Articles

Eltrombopag Specifically Expands Hematopoietic Multipotent Progenitors in Human Aplastic Anemia

Bruno Quintino Oliveira, brunoqolvr@gmail.com, Bárbara Santana, PhD, Luiz Fernando Bazzo Catto, MDPhD, Maria Florencia Tellechea, PhD, Priscila Santos Scheucher, PhD, Phillip Scheinberg, MD, Rodrigo T. Calado, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23.
https://doi.org/10.1182/blood-2020-142746
Published: 2020
Journal Articles

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

Thiago Mantello Bianco, MSc, Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Priscila Santos Scheucher, PhD, Isabel Weinhäuser, MSc, Antonio Bruno Alves Silva, BSc, Cleide Lucia Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo M Rego, MD PhD, Fabiola Traina, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2977.
https://doi.org/10.1182/blood-2019-131023
Published: 2019
Journal Articles

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Izabela Aparecida Lopes, MSc, Miroslava Kardosova, MSc, Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Cleide Araújo Silva, MSc, Priscila Santos Scheucher, PhD, Daniel G. Tenen, MD, Sanghoon Lee, PhD, Eduardo Magalhães Rego, MD PhD, Robert S. Welner, PhD, Meritxell Alberich-Jorda, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3721.
https://doi.org/10.1182/blood-2018-99-119389
Published: 2018
Journal Articles

Autophagy Inhibition Potentiates Ruxolitinib-Induced Apoptosis in JAK2 V617F Cells

João Agostinho Machado-Neto, BSc, Juan Luiz Coelho-Silva, BSc, MSc, Fábio Pires de Souza Santos, MD PhD, Priscila Santos Scheucher, PhD, Paulo Vidal Campregher, MD PhD, Nelson Hamerschlak, MD PhD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1788.
https://doi.org/10.1182/blood-2018-99-119651
Published: 2018
Journal Articles

Imbalance between Tolerant and Cytotoxic Functional Subsets of NK Cells in a JAK2 V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Izabela Aparecida Lopes, MSc, Priscila Santos Scheucher, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MDPhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4221.
https://doi.org/10.1182/blood.V130.Suppl_1.4221.4221
Published: 2017
Journal Articles

IGF Signaling Predicts Outcomes and Is a Promising Target Therapy for Acute Myeloid Leukemia

Juan Luiz Coelho-Silva, BSc, MSc, João Agostinho Machado-Neto, BSc, Jaqueline Cristina Fernandes, BSc, MSc, Ana Silvia G de Lima, PhD, Priscila Santos Scheucher, PhD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3966.
https://doi.org/10.1182/blood.V130.Suppl_1.3966.3966
Published: 2017
Journal Articles

The Pharmacological IGF1R-IRS1/2 Inhibitor NT157 Presents Multiple Anti-Neoplastic Effects in Myeloproliferative Neoplasms

Bruna Alves Fenerich, BSc, João Agostinho Machado-Neto, BSc, Ana Paula Nunes Rodrigues Alves, MSc, Paula De Melo Campos, MD PhD, Jaqueline Cristina Fernandes, BSc, MSc, Juan Luiz Coelho-Silva, BSc, MSc, Renata Scopim Ribeiro, BSc, MSc, Fernanda B da Silva, BSc and MSc, Priscila Santos Scheucher, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1253.
https://doi.org/10.1182/blood.V130.Suppl_1.1253.1253
Published: 2017
Journal Articles

Pharmacological IRS1/2 Inhibition Induces Apoptosis in BCR-ABL1 T315I mutant Cells

Renata Scopim-Ribeiro, M.Sc., João Agostinho Machado-Neto, PhD, Christopher A. Eide, Paula de Melo Campos, PhD, Priscila Santos Scheucher, PhD, Sara Teresinha Olalla Saad, MD PhD, Eduardo Magalhães Rego, MD, PhD, Cristina E. Tognon, Brian J. Druker, MD, Fabiola Traina, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 1886.
https://doi.org/10.1182/blood.V128.22.1886.1886
Published: 2016
Journal Articles

Multitarget Antileukemic Effects of Metformin in Myeloproliferative Neoplasm Cells: Inhibition of JAK2/STAT Signaling and Mitochondrial Activity

João Agostinho Machado-Neto, PhD, Bruna Alves Fenerich, B.Sc., Renata Scopim-Ribeiro, M.Sc., Carlos Roberto Porto Dechandt, B.Sc., Ana Paula Nunes Rodrigues Alves, M.Sc., Jaqueline Cristina Fernandes, B.Sc., Priscila Santos Scheucher, PhD, Belinda Pinto Simões, MD, PhD, Luciane Carla Alberici, PhD, Lorena Lôbo de Figueiredo Pontes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 1960.
https://doi.org/10.1182/blood.V128.22.1960.1960
Published: 2016
Journal Articles

Pharmacological IGF1R/IRS Inhibitor, NT157, Effectively Induces Apoptosis and CDKN1A Expression in Acute Lymphoblastic Leukemia Cells

Ana Paula Nunes Rodrigues Alves, M.Sc., João Agostinho Machado-Neto, PhD, Jaqueline Cristina Fernandes, B.Sc., Bruna Alves Fenerich, B.Sc., Fernanda Borges da Silva, B.Sc., Priscila Santos Scheucher, PhD, Belinda Pinto Simões, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 3971.
https://doi.org/10.1182/blood.V128.22.3971.3971
Published: 2016
Journal Articles

Pharmacological IRS1/2 Inhibition Reduces Cell Viability in BCR-ABL1 Positive Cells

Renata Scopim-Ribeiro, M.Sc., João Agostinho Machado-Neto, PhD, Paula de Melo Campos, PhD, Adriana da Silva Santos Duarte, PhD, Priscila Santos Scheucher, PhD, Amélia Góes, PhD, Sara Teresinha Olalla Saad, MD, PhD, Belinda Pinto Simoes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 2772.
https://doi.org/10.1182/blood.V126.23.2772.2772
Published: 2015
Journal Articles

Decreased Activity of NK Cells in Myeloproliferative Neoplasms

Adriana Queiroz Arantes, MD, Cristina Tavares Leal, MD, Cleide Araújo Silva, Priscila Santos Scheucher, PhD, Aglair Bergamo, Robert S. Welner, PhD, Daniel G. Tenen, MD, Ann Mullally, MD, Susumu Kobayashi, MD PhD, Eduardo Magalhaes Rego, PhD, Lorena Lobo Figueiredo-Pontes, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1637.
https://doi.org/10.1182/blood.V126.23.1637.1637
Published: 2015
Journal Articles

LAT2, a Lipid Raft Protein That Participates in AKT Phosphorylation in Mantle Cell Lymphoma, Is a Target for Perifosine Chemotherapy

Germano A Ferreira, PhD, Carolina H Thomé, PhD, Priscila Santos Scheucher, PhD, Andréia M Leopoldino, Prof. PhD, Ana Maria Simão, PhD, Clarice Izumi, PhD, Pietro Ciancaglini, Prof. PhD, Vitor Marcel Faça, Prof, PhD, Lewis Joel Greene, Prof. PhD, Guilherme A Santos, MD PhD, Eduardo M Rego, Prof, MD PhD
Journal: Blood
Blood (2014) 124 (21): 923.
https://doi.org/10.1182/blood.V124.21.923.923
Published: 2014
Journal Articles

Better Performance of Flow-FISH in Comparison to qPCR As a Diagnostic Test for Telomere Diseases

Fernanda Gutierrez-Rodrigues, PhDstudent, Bárbara A Santana-Lemos, PhD, Priscila Santos Scheucher, PhD, Raquel M Alves-Paiva, PhD, Rodrigo T. Calado, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1605.
https://doi.org/10.1182/blood.V124.21.1605.1605
Published: 2014