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Journal Articles

Endoplasmic Reticulum to Mitochondria Ca 2+ Signaling Inhibits Factor VIII Secretion and Mediates Oxidative Stress and Apoptosis Upon Factor VIII Expression

Jyoti Malhotra, Mon Xiong, Hongzhi Miao, Steven Pipe, Randal J. Kaufman, PhD

Blood (2010) 116 (21): 2212.

https://doi.org/10.1182/blood.V116.21.2212.2212

Published: 2010

Journal Articles

Factor VIII Biosynthesis and the Unfolded Protein Response.

Randal J. Kaufman, PhD

Blood (2009) 114 (22): SCI-19.

https://doi.org/10.1182/blood.V114.22.SCI-19.SCI-19

Published: 2009

Journal Articles

Incremental Improvement in Bioengineering of Coagulation Factor VIII for Efficient Expression: Elimination of a Dispensable Disulfide Loop Enhances Secretion

Sundar Rajan Selvaraj, PhD, Randal J Kaufman, PhD, Steven W. Pipe, MD

Blood (2008) 112 (11): 3073.

https://doi.org/10.1182/blood.V112.11.3073.3073

Published: 2008

Journal Articles

Inactivation-Resistant Recombinant Factor VIII Exhibits Superior Thrombin Generation Capacity in Comparison to Wild-Type and B Domain-Deleted Factor VIII.

Joshua Russell, Yesim Dargaud, MD, Randal J. Kaufman, PhD, Claude Negrier, MD, PhD, Steven W. Pipe, MD

Blood (2006) 108 (11): 1604.

https://doi.org/10.1182/blood.V108.11.1604.1604

Published: 2006

Journal Articles

Mutations in LMAN1 and MCFD2 May Account for All Cases of Combined Deficiency of Factor V and Factor VIII.

Bin Zhang, PhD, Beth McGee, BS, William C. Nichols, PhD, Hugo Guglielmone, M.Sc, Katherine Downes, MD, Flora Peyvandi, MD, Norma B. de Bosch, MD, Arlette Ruiz-Saez, MD, Bernard Chatelain, MD, Marian Olpinski, MD, Paula Bockenstedt, MD, Wolfgang Sperl, MD, Randal J. Kaufman, PhD, David Ginsburg, MD

Blood (2005) 106 (11): 724.

https://doi.org/10.1182/blood.V106.11.724.724

Published: 2005

Journal Articles

The Secretion Efficiency of Factor VIII Can Be Regulated by the Size and Oligosaccharide Content of the B Domain.

Steven W. Pipe, MD, Hongzhi Z. Miao, Philip F. Kucab, John H. McVey, PhD, Randal J. Kaufman, PhD

Blood (2005) 106 (11): 687.

https://doi.org/10.1182/blood.V106.11.687.687

Published: 2005

NARROW

Endoplasmic Reticulum to Mitochondria Ca 2+ Signaling Inhibits Factor VIII Secretion and Mediates Oxidative Stress and Apoptosis Upon Factor VIII Expression

Factor VIII Biosynthesis and the Unfolded Protein Response.

Incremental Improvement in Bioengineering of Coagulation Factor VIII for Efficient Expression: Elimination of a Dispensable Disulfide Loop Enhances Secretion

Inactivation-Resistant Recombinant Factor VIII Exhibits Superior Thrombin Generation Capacity in Comparison to Wild-Type and B Domain-Deleted Factor VIII.

Mutations in LMAN1 and MCFD2 May Account for All Cases of Combined Deficiency of Factor V and Factor VIII.

The Secretion Efficiency of Factor VIII Can Be Regulated by the Size and Oligosaccharide Content of the B Domain.

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ASH Publications

American Society of Hematology

Endoplasmic Reticulum to Mitochondria Ca 2+ Signaling Inhibits Factor VIII Secretion and Mediates Oxidative Stress and Apoptosis Upon Factor VIII Expression

Factor VIII Biosynthesis and the Unfolded Protein Response.

Incremental Improvement in Bioengineering of Coagulation Factor VIII for Efficient Expression: Elimination of a Dispensable Disulfide Loop Enhances Secretion

Inactivation-Resistant Recombinant Factor VIII Exhibits Superior Thrombin Generation Capacity in Comparison to Wild-Type and B Domain-Deleted Factor VIII.

Mutations in LMAN1 and MCFD2 May Account for All Cases of Combined Deficiency of Factor V and Factor VIII.

The Secretion Efficiency of Factor VIII Can Be Regulated by the Size and Oligosaccharide Content of the B Domain.

Email alerts

ASH Publications

American Society of Hematology

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