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Journal Articles

Development of CD38 CAR Engineered Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells (PNK-CAR38) As Allogeneic Cancer Immunotherapy

Srinivas Somanchi, PhD, Xuan Guo, PhD, Shuyang He, PhD, Rohit Mathur, PhD, Andrea Difiglia, BS, Hemlata Rana, MS, Weifang Ling, PhD, James Edinger, PhD, Gunnar F. Kaufmann, PhD, Jerome B. Zeldis, MD PhD, Henry Ji, PhD, Robert Hariri, MD PhD, Xiaokui Zhang, PhD

Blood (2019) 134 (Supplement_1): 2070.

https://doi.org/10.1182/blood-2019-129539

Published: 2019

Journal Articles

Engineering High Affinity and Cleavage Resistant CD16 to Augment ADCC of Placental Hematopoietic Stem Cells-Derived Natural Killer Cells

Xuan Guo, PhD, Srinivas Somanchi, PhD, Rohit Mathur, PhD, Shuyang He, PhD, Qian Ye, PhD, Andrea Difiglia, BS, Salvatore Rotondo, MS, Hemlata Rana, MS, Weifang Ling, PhD, James Edinger, PhD, Robert Hariri, MD PhD, Xiaokui Zhang, PhD

Blood (2019) 134 (Supplement_1): 1576.

https://doi.org/10.1182/blood-2019-127009

Published: 2019

Journal Articles

Adoptive T-Cell Therapy with TCL1-Specific TCR for B-Cell Lymphomas

Jinsheng Weng, MD PhD, Kelsey Moriarty, BD, Yong Pan, Man Chun John MA, PhD, Rohit Mathur, PhD, Zheng Zhang, Hiroki Torikai, MD, Sourindra N Maiti, Fuliang Chu, PhD, Xiaoyun Cheng, Swathi Karri, Deepshika Medapalli, Laurence J N Cooper, MD PhD, R. Eric Davis, MD, Sattva S. Neelapu, MD

Blood (2018) 132 (Supplement 1): 3488.

https://doi.org/10.1182/blood-2018-99-115424

Published: 2018

Journal Articles

B-Cell Maturation Antigen (BCMA)-Specific, Centyrin TM -Based, PiggyBac TM -Transposed CAR-T Memory Stem Cells Are Effective Against p53 -/- and Patient-Derived Multiple Myeloma Tumors

Blood (2017) 130 (Supplement 1): 3068.

https://doi.org/10.1182/blood.V130.Suppl_1.3068.3068

Published: 2017

Journal Articles

Pilot Study of Pembrolizumab for Immunoprevention in Smoldering Multiple Myeloma

Elisabet E. Manasanch, MD, Rohit Mathur, PhD, Hans C. Lee, MD, Donna M. Weber, MD, Krina K. Patel, MDMSc, Sheeba K. Thomas, MD, Silvia C. Munoz, RN, Claudia Morales de Partovi, Catherine M. Claussen, MS, Pei Lin, MDDM,MDC, Behrang Amini, MD, Linghua Wang, Man Chun John MA, PhD, Yun Qing, Feng Lei, MS, Veera Baladandayuthapani, PhD, R. Eric Davis, MD, Sattva S. Neelapu, MD, Robert Z. Orlowski, MD PhD

Blood (2017) 130 (Supplement 1): 3089.

https://doi.org/10.1182/blood.V130.Suppl_1.3089.3089

Published: 2017

Journal Articles

Universal SLAMF7-Specific CAR T-Cells As Treatment for Multiple Myeloma

Rohit Mathur, PhD, Zheng Zhang, Jin He, Roman Galetto, PhD, Agnès Gouble, PhD, Isabelle Chion-Sotinel, Stéphanie Filipe, PhD, Annabelle Gariboldi, Tanooha Veeramachaneni, Elisabet E. Manasanch, MD, Sheeba K. Thomas, MD, Hans C. Lee, MD, Krina K. Patel, MDMSc, Donna M. Weber, MD, R. Eric Davis, MD, Robert J. Orlowski, MD PhD, Julianne Smith, PhD, Jing Yang, PhD, Sattva S. Neelapu, MD

Blood (2017) 130 (Supplement 1): 502.

https://doi.org/10.1182/blood.V130.Suppl_1.502.502

Published: 2017

Journal Articles

A Novel Bcma-Specific, Centyrin-Based CAR-T Product for the Treatment of Multiple Myeloma

David L. Hermanson, PhD, Burton Earle Barnett, PhD, Srinivas Rengarajan, M.S., Rebecca Codde, B.S., Xinxin Wang, PhD, Yening Tan, B.S., Christopher E. Martin, PhD, Jenessa Barbara Smith, PhD, Jin He, M.S., Rohit Mathur, PhD, Jing Yan, PhD, Sattva S. Neelapu, MD, Eric M. Osertag, MD PhD, Devon J. Shedlock, PhD

Blood (2016) 128 (22): 2127.

https://doi.org/10.1182/blood.V128.22.2127.2127

Published: 2016

Journal Articles

Tumor Microenvironment Regulates Survival of Mantle Cell Lymphoma Cells through Various Signaling Pathways

Lalit Sehgal, PhD, Khashab Tamer, MD, Xin Wang, MD, Rohit Mathur, PhD, Zuzana Berkova, PhD, Jorge E. Romaguera, MD, Alma Rodriguez, MD, Sattva S. Neelapu, MD, Felipe Samaniego, MD

Blood (2015) 126 (23): 4775.

https://doi.org/10.1182/blood.V126.23.4775.4775

Published: 2015

Journal Articles

Accelerated Degradation of cFLIP Mediated By Inhibition of Methyltransferases Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

Frank K Braun, PhD, Rohit Mathur, PhD, Lalit Sehgal, PhD, Rachel Wilkie-Grantham, Joya Chandra, PhD, Zuzana Berkova, PhD, Felipe Samaniego, MD

Blood (2014) 124 (21): 920.

https://doi.org/10.1182/blood.V124.21.920.920

Published: 2014

Journal Articles

Molecular Signatures of Tumor-Initiating Cells Unveil Wnt Pathway As a Therapeutic Target in Mantle Cell Lymphoma

Felipe Samaniego, MD, Lalit Sehgal, PhD, Frank K Braun, PhD, Zuzana Berkova, PhD, Jorge E. Romaguera, MD, Michael Wang, MD, M. Alma Rodriguez, MD, Sattva S Neelapu, MD, Rohit Mathur, PhD

Blood (2014) 124 (21): 2148.

https://doi.org/10.1182/blood.V124.21.2148.2148

Published: 2014

Journal Articles

Human Mesenchymal Stem Cells Promote Resistance to Death Signals By Potentiating FGF Signaling in Mantle Cell Lymphoma

Lalit Sehgal, PhD, Rohit Mathur, PhD, Frank K Braun, PhD, Zuzana Berkova, PhD, Sattva Neelapu, MD, Felipe Samaniego, MD

Blood (2014) 124 (21): 5119.

https://doi.org/10.1182/blood.V124.21.5119.5119

Published: 2014

Journal Articles

Histone 3 Methyltransferase (EZH2) Inhibition Enhances TRAIL-Induced Apoptosis In Mantle Cell Lymphoma Cells By Accelerated cFLIP Degradation

Frank K Braun, PhD, Rohit Mathur, PhD, Lalit Sehgal, Ph.D, Zuzana Berkova, PhD, Felipe Samaniego, M.D., M.P.H

Blood (2013) 122 (21): 4425.

https://doi.org/10.1182/blood.V122.21.4425.4425

Published: 2013

Journal Articles

A Single Center Phase II Trial Of 90 yttrium-Ibritumomab-Tiuxetan Produces High Response Rates As First-Line Therapy For Early Stage B Cell Indolent Lymphoma, Including Bulky Disease

Felipe Samaniego, M.D., M.P.H, Jorge E Romaguera, MD, Nathan Fowler, MD, Michelle A. Fanale, MD, Jatin J. Shah, M.D., Peter McLaughlin, MD, Barbara Pro, MD, Vijairam Selvaraj, MD, Frank K Braun, PhD, Rohit Mathur, PhD, Lei Feng, M.S., Sattva Neelapu, MD, Larry W. Kwak, MD, PhD

Blood (2013) 122 (21): 3039.

https://doi.org/10.1182/blood.V122.21.3039.3039

Published: 2013

Journal Articles

FAS-AS1 Intronic Lncrna and Ibrutinib Negatively Regulate Soluble Fas Production and Sensitize B-Cell Lymphomas To Fas-Mediated Apoptosis

Lalit Sehgal, Ph.D, Frank K Braun, PhD, Rohit Mathur, PhD, Sattva Neelapu, MD, Larry W. Kwak, MD, PhD, Zuzana Berkova, PhD, Felipe Samaniego, M.D., M.P.H

Blood (2013) 122 (21): 5051.

https://doi.org/10.1182/blood.V122.21.5051.5051

Published: 2013

Journal Articles

Nucleolin inhibits Fas ligand binding and suppresses Fas-mediated apoptosis in vivo via a surface nucleolin-Fas complex

Jillian F. Wise, Zuzana Berkova, Rohit Mathur, Haifeng Zhu, Frank K. Braun, Rong-Hua Tao, Anita L. Sabichi, Xue Ao, Hoyoung Maeng, Felipe Samaniego

Blood (2013) 121 (23): 4729–4739.

https://doi.org/10.1182/blood-2012-12-471094

Published: 2013

Includes: Supplemental data

Journal Articles

Mechanism of Regulating Fas Signaling by Promyelocytic Leukemia Protein (PML) and Its Dominant-Negative Mutant PMLRARα

Rong-Hua Tao, M.D., Ph.D., Zuzana Berkova, PhD, Jillian F Wise, B.S., Haifeng Zhu, Ph.D., Xue Ao, MS, Zeming Chen, PhD, Wenzhuo Zhuang, PhD, Frank K Braun, PhD, Rohit Mathur, PhD, Felipe Samaniego, M.D.

Blood (2012) 120 (21): 1327.

https://doi.org/10.1182/blood.V120.21.1327.1327

Published: 2012

Journal Articles

Regulation of Fas-mediated Apoptosis in B-Cell Lymphomas by Nucleolin.

Felipe Samaniego, MD, MPH, Jillian F Wise, BS, Rong-Hua Tao, MD, PhD, Haifeng Zhu, PhD, Xue Ao, MS, Zeming Chen, PhD, Wenzhuo Zhuang, PhD, Frank K Braun, PhD, Rohit Mathur, PhD, Jorge Enrique Romaguera, MD, Luis Fayad, MD, Michael Wang, MD, Peter McLaughlin, MD, Timothy J. McDonnell, MD, PhD, Keyur P. Patel, MD, PhD, Sattva S. Neelapu, MD, Larry W. Kwak, MD, PhD, Zuzana Berkova, PhD

Blood (2012) 120 (21): 2406.

https://doi.org/10.1182/blood.V120.21.2406.2406

Published: 2012

NARROW

Development of CD38 CAR Engineered Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells (PNK-CAR38) As Allogeneic Cancer Immunotherapy

Engineering High Affinity and Cleavage Resistant CD16 to Augment ADCC of Placental Hematopoietic Stem Cells-Derived Natural Killer Cells

Adoptive T-Cell Therapy with TCL1-Specific TCR for B-Cell Lymphomas

B-Cell Maturation Antigen (BCMA)-Specific, Centyrin TM -Based, PiggyBac TM -Transposed CAR-T Memory Stem Cells Are Effective Against p53 -/- and Patient-Derived Multiple Myeloma Tumors

Pilot Study of Pembrolizumab for Immunoprevention in Smoldering Multiple Myeloma

Universal SLAMF7-Specific CAR T-Cells As Treatment for Multiple Myeloma

A Novel Bcma-Specific, Centyrin-Based CAR-T Product for the Treatment of Multiple Myeloma

Tumor Microenvironment Regulates Survival of Mantle Cell Lymphoma Cells through Various Signaling Pathways

Accelerated Degradation of cFLIP Mediated By Inhibition of Methyltransferases Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

Molecular Signatures of Tumor-Initiating Cells Unveil Wnt Pathway As a Therapeutic Target in Mantle Cell Lymphoma

Human Mesenchymal Stem Cells Promote Resistance to Death Signals By Potentiating FGF Signaling in Mantle Cell Lymphoma

Histone 3 Methyltransferase (EZH2) Inhibition Enhances TRAIL-Induced Apoptosis In Mantle Cell Lymphoma Cells By Accelerated cFLIP Degradation

A Single Center Phase II Trial Of 90 yttrium-Ibritumomab-Tiuxetan Produces High Response Rates As First-Line Therapy For Early Stage B Cell Indolent Lymphoma, Including Bulky Disease

FAS-AS1 Intronic Lncrna and Ibrutinib Negatively Regulate Soluble Fas Production and Sensitize B-Cell Lymphomas To Fas-Mediated Apoptosis

Nucleolin inhibits Fas ligand binding and suppresses Fas-mediated apoptosis in vivo via a surface nucleolin-Fas complex

Mechanism of Regulating Fas Signaling by Promyelocytic Leukemia Protein (PML) and Its Dominant-Negative Mutant PMLRARα

Regulation of Fas-mediated Apoptosis in B-Cell Lymphomas by Nucleolin.

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American Society of Hematology

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American Society of Hematology

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