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Ryan P. Larson
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Journal Articles

In vivo CAR T-cell generation in nonhuman primates using lentiviral vectors displaying a multidomain fusion ligand

Christopher J. Nicolai, Maura H. Parker, Jim Qin, Weiliang Tang, Justin T. Ulrich-Lewis, Rebecca J. Gottschalk, Sara E. Cooper, Susana A. Hernandez Lopez, Don Parrilla, Richard S. Mangio, Nolan G. Ericson, Alissa H. Brandes, Saluwa Umuhoza, Kathryn R. Michels, Mollie M. McDonnell, Lisa Y. Park, Seungjin Shin, Wai-Hang Leung, Andrew M. Scharenberg, Hans-Peter Kiem, Ryan P. Larson, Laurie O. Beitz, Byoung Y. Ryu
Journal: Blood
Blood (2024) 144 (9): 977–987.
https://doi.org/10.1182/blood.2024024523
Published: 2024
Includes: Supplemental data
Journal Articles

Vivovec™ Surface-Engineered Lentiviral Particles Mediate In Vivo CAR T Generation with Potent and Highly Durable Activity in Non-Human Primates and Tumor-Bearing Humanized Mice

Maura Parker, Justin Ulrich-Lewis, Weiliang Tang, Chris Nicolai, Kathryn Michels, Susana Hernandez, Don Parrilla, Sara Cooper, Anai Perez, Mollie McDonnell, Greyson Hamilton, Chang-Chih Wu, Seungjin Shin, Andrew M. Scharenberg, Ryan P. Larson, Laurie Beitz, Byoung Y. Ryu
Journal: Blood
Blood (2023) 142 (Supplement 1): 765.
https://doi.org/10.1182/blood-2023-182195
Published: 2023
Journal Articles

Statistical Learning Approaches for Predicting Lisocabtagene Maraleucel (liso-cel) Drug Product Composition from Donor-Selected Material Composition

Yue Jiang, PhD, Afshin Mashadi-Hossein, MSc, Rachel Yost, Jeffrey Teoh, PhD, Ryan P. Larson, PhD, Ronald J. Hause, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 591.
https://doi.org/10.1182/blood-2019-125801
Published: 2019
Journal Articles

Lisocabtagene Maraleucel (liso-cel) Manufacturing Process Control and Robustness across CD19+ Hematological Malignancies

Jeffrey Teoh, PhD, Timothy G. Johnstone, PhD, Brian Christin, BS, Rachel Yost, Neil A. Haig, Mary Mallaney, Aditya Radhakrishnan, Heidi H. Gillenwater, MD, Tina Albertson, MD, Paul Guptill, Lauren F. Brown, Christopher G. Ramsborg, Ronald J. Hause, PhD, Ryan P. Larson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 593.
https://doi.org/10.1182/blood-2019-127150
Published: 2019
Journal Articles

JCAR017 Is a Defined Composition CAR T Cell Product with Product and Process Controls That Deliver Precise Doses of CD4 and CD8 CAR T Cell to Patients with NHL

Christopher G. Ramsborg, PhD, Paul Guptill, Clinton Weber, BS, Brian Christin, BS, Ryan P Larson, PhD, Kenneth Lewis, PhD, Mary Mallaney, Michael Bowen, PhD, Eileen Higham, PhD, Tina Albertson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4471.
https://doi.org/10.1182/blood.V130.Suppl_1.4471.4471
Published: 2017
Journal Articles

Identification of Small Molecule Modulators to Enhance the Therapeutic Properties of Chimeric Antigen Receptor T Cells

Jonathan Rosen, PhD, Betsy Rezner, BS, David Robbins, BS, Ian Hardy, PhD, Eigen Peralta, PhD, Christian Maine, PhD, Mohsen Sabouri, Sarah Reynal, Christopher Truong, Stacey Moreno, Heather Foster, Sarah Borchelt, Miguel Meza, MS, Lucas Thompson, Jason Fontenot, PhD, Ryan P Larson, PhD, Mirna Mujacic, PhD, Daniel Shoemaker, PhD
Journal: Blood
Blood (2016) 128 (22): 4712.
https://doi.org/10.1182/blood.V128.22.4712.4712
Published: 2016
Journal Articles

Functional Characterization of a T Cell Stimulation Reagent for the Production of Therapeutic Chimeric Antigen Receptor T Cells

Keenan T Bashour, PhD, Ryan P Larson, PhD, Patricia Graef, PhD, Christian Stemberger, PhD, Germeroth Lothar, PhD, Valerie Odegard, PhD, Christopher G Ramsborg, PhD
Journal: Blood
Blood (2015) 126 (23): 1901.
https://doi.org/10.1182/blood.V126.23.1901.1901
Published: 2015
Journal Articles

Preclinical Analyses Support Clinical Investigation of Combined PD-L1 Blockade and Anti-CD19 CAR T Cell Therapy for the Treatment of NHL

Ryan P Larson, PhD, Michael Ports, PhD, Heidi Jessup, Guadalupe Manriquez, MD, Carl Hay, Ross Stewart, PhD, Marlon Rebelatto, DVM, PhD, Robert Hollingsworth, PhD, Valerie Odegard, PhD
Journal: Blood
Blood (2015) 126 (23): 5430.
https://doi.org/10.1182/blood.V126.23.5430.5430
Published: 2015