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Journal Articles

Selective Inhibition of Nuclear Cytoplasmic Transport As a New Treatment Paradigm in Myelofibrosis

Dongqing Yan, PhD, Srinivas K. Tantravahi, MD, Anthony D. Pomicter, MS, Anna Senina, MS, Kevin C. Gantz, Hannah M. Redwine, Josef T. Prchal, MD, Sabina Swierczek, PhD, Phillip M. Clair, MS, Anna M. Eiring, PhD, Erkan Baloglu, PhD MBA, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2016) 128 (22): 636.

https://doi.org/10.1182/blood.V128.22.636.636

Published: 2016

Journal Articles

Focal Reactivation of Some X-Chromosome Genes in PV and ET Clones

Soo Jin Kim, MS, Sabina Swierczek, PhD, Jihyun Song, PhD, Jaroslav Jelinek, MD PhD, Josef T. Prchal, MD

Blood (2016) 128 (22): 1966.

https://doi.org/10.1182/blood.V128.22.1966.1966

Published: 2016

Journal Articles

Upregulation of Thrombo-Inflammatory Pathways May Contribute to Increased Thrombotic Risk in Polycythemia Vera and Essential Thrombocythemia

Radhika Gangaraju, MD, Soo Jin Kim, MS, Jihyun Song, PhD, Sabina Swierczek, PhD, Perumal Thiagarajan, MD, Josef T. Prchal, MD

Blood (2016) 128 (22): 3143.

https://doi.org/10.1182/blood.V128.22.3143.3143

Published: 2016

Journal Articles

The Effect of IV Iron Therapy on HIF Pathway and HIF Regulated Genes in Elderly Patients with Unexplained Anemia

Levon Katsakhyan, BS, Sabina Swierczek, PhD, Andrew Artz, MD MS, Elizabeth A Price, MD MPH, Stanley L. Schrier, MD, Harvey Jay Cohen, MD, Josef T. Prchal, MD, Victor R. Gordeuk, MD

Blood (2015) 126 (23): 4533.

https://doi.org/10.1182/blood.V126.23.4533.4533

Published: 2015

Journal Articles

Reactivation of the X-Chromosome Genes within PV Clone

Soo Jin Kim, MS, Jaroslav Jelinek, MD PhD, Jean-Pierre J Issa, MD, Josef T. Prchal, MD, Sabina Swierczek, PhD

Blood (2015) 126 (23): 4086.

https://doi.org/10.1182/blood.V126.23.4086.4086

Published: 2015

Journal Articles

Calreticulin mutations Are Present in Polyclonal As Well As Clonal ET

Xylina Gregg, MD, Sabina Swierczek, PhD, Soo Jin Kim, MS, Josef T. Prchal, MD

Blood (2014) 124 (21): 4590.

https://doi.org/10.1182/blood.V124.21.4590.4590

Published: 2014

Journal Articles

Focal Reactivation of X-Chromosome in Female Patients with PV and ET

Soo Jin Kim, MS, Sabina Swierczek, PhD, Jihyun Song, MS, Jean-Pierre Issa, MD, Jaroslav Jelinek, MD PhD, Josef T. Prchal, MD

Blood (2014) 124 (21): 3225.

https://doi.org/10.1182/blood.V124.21.3225.3225

Published: 2014

Journal Articles

Effect of a TNFα Blocker and Peginfa on Polycythemia Vera Clonal Hematopoiesis and Suppressed Normal Dormant Hematopoiesis

Sabina Swierczek, PhD, Soo Jin Kim, MS, Mohamed E Salama, MD, William L. Heaton, M.S., Michael W. Deininger, Josef T. Prchal, MD

Blood (2014) 124 (21): 1820.

https://doi.org/10.1182/blood.V124.21.1820.1820

Published: 2014

Journal Articles

HIF-Mediated Changes in Erythropoiesis and Gene Expression in Chronic Intermittent Hypoxia Due to Obstructive Sleep Apnea

Jack C. Weis, Krishna Sundar, Song Jihyun, MS, Sabina Swierczek, PhD, Josef T. Prchal, MD

Blood (2014) 124 (21): 1334.

https://doi.org/10.1182/blood.V124.21.1334.1334

Published: 2014

Journal Articles

Autocrine TNF-α Signaling in Hematopoietic Stem Cells Promotes Myeloproliferative Disease Progression through Activation of TNFR2

William L. Heaton, M.S., Anna V. Senina, M.S., Anthony D. Pomicter, M.S., James E Marvin, M.S., Sabina Swierczek, PhD, Anna M. Eiring, PhD, Josef T. Prchal, MD, Thomas O'Hare, Michael W. Deininger

Blood (2014) 124 (21): 1888.

https://doi.org/10.1182/blood.V124.21.1888.1888

Published: 2014

Journal Articles

Ph-Negative Myeloproliferative Neoplasms Exhibit Some Features Of Warburg Effect

Sherjeel Sana, MD, Maria Navas-Mareno, PhD, Z.Valey Vardney, PhD, Mark Duros, MS, Felipe R Lorenzo V, PhD, Katarina Kapralova, MSc, Sabina Swierczek, PhD, Josef Prchal, MD

Blood (2013) 122 (21): 1604.

https://doi.org/10.1182/blood.V122.21.1604.1604

Published: 2013

Journal Articles

Molecular Characterization Of Polycythemia Vera Based On The Relationship Of JAK2 V617F and 9pUPD

Linghua Wang, MD, PhD, Sabina Swierczek, PhD, Kimberly Hickman, Soo-Jin Kim, David A. Wheeler, PhD, Josef Prchal, MD

Blood (2013) 122 (21): 1607.

https://doi.org/10.1182/blood.V122.21.1607.1607

Published: 2013

Journal Articles

Hemopoietic Stem Cells In Polycythemia Vera and Essential Thrombocythemia Have Increased TNF-Alpha That Decreases After Pegylated Interferon-a Therapy, But Not Hydroxyurea, and Correlates With Suppression Of PV and ET Clones

Sabina Swierczek, PhD, Mohamed E Salama, MD, Katherine King, MD, PhD, Andrew Wilson, PhD, Sheryl Tripp, MD, Sherrie L. Perkins, MD, PhD, Margaret A. Goodell, PhD, Josef T. Prchal, MD

Blood (2013) 122 (21): 2827.

https://doi.org/10.1182/blood.V122.21.2827.2827

Published: 2013

Journal Articles

Pegifna Promotes Proliferation and Myeloid Differentiation In Human Hematopoietic Progenitors In Patients With Polycythemia Vera and Essential Thrombocythemia

Katherine King, MD, PhD, Sabina Swierczek, PhD, Katie Matatall, PhD, Kimberly Hickman, Margaret A. Goodell, PhD, Josef Prchal, MD

Blood (2013) 122 (21): 2843.

https://doi.org/10.1182/blood.V122.21.2843.2843

Published: 2013

Journal Articles

A Novel EPO Gene Mutation In a Family With Autosomal Dominant Polycythemia

Felipe R Lorenzo V, PhD, Rebecca Margraf, PhD, Sabina Swierczek, PhD, Kimberly Hickman, Karl Voelkerding, MD, Josef Prchal, MD

Blood (2013) 122 (21): 950.

https://doi.org/10.1182/blood.V122.21.950.950

Published: 2013

Journal Articles

The Number Of Peripheral Blood CD4+CD25+FOXP3+ Regulatory T-Cells Is a Marker Of Response In Patients With JAK2 V617F Positive Myeloproliferative Neoplasms Treated With Pegylated-Interferon-α

Todd W. Kelley, MD, Sabina Swierczek, PhD, Olga Efimova, MD, Andrew R. Wilson, PhD, Soo Jin Kim, MS, Josef Prchal, MD

Blood (2013) 122 (21): 4059.

https://doi.org/10.1182/blood.V122.21.4059.4059

Published: 2013

Journal Articles

A Novel EGLN1/PHD2 High-Frequency Variant in Tibetans Protects Against Hypoxia-Induced Polycythemia.

Felipe R Lorenzo V, M.D., PhD., Chad Daniel Huff, PhD, Mikko Myllymäki, Sabina Swierczek, PhD, Mohamed E Salama, M.D., Gregg Semenza, MD, PhD, Victor R. Gordeuk, MD, Lynn Jorde, Prof., Peppi Koivunen, MD, PhD, Josef T. Prchal, MD

Blood (2012) 120 (21): 2079.

https://doi.org/10.1182/blood.V120.21.2079.2079

Published: 2012

Journal Articles

Salutary Effect of Pegylated Interferona in PV and ET As Evaluated by Quantitation of Pre- JAK2 V617F and JAK2 V617F -Bearing Stem Cells and Granulocytes and Correlation with Circulating Regulatory T Cells and HSC Cell Cycle Status

Sabina Swierczek, PhD, Todd W. Kelley, MD, Katherine Y King, M.D., Ph.D., Shen Ching-Chieh, Kimberly Hickman, BS, Soo Jin Kim, M.S., Mohamed E Salama, M.D., Margaret A. Goodell, PhD, Josef T. Prchal, MD

Blood (2012) 120 (21): 807.

https://doi.org/10.1182/blood.V120.21.807.807

Published: 2012

Journal Articles

Whole Exome Sequencing of Polycythemia Vera Reveals Novel Recurrent Somatic and Germline Variation

Linghua Wang, PhD, Sabina Swierczek, PhD, Lucie Piterkova, PhD, Kimberly Hickman, David A. Wheeler, PhD, Josef T. Prchal, MD

Blood (2012) 120 (21): 705.

https://doi.org/10.1182/blood.V120.21.705.705

Published: 2012

Journal Articles

The Tibetan PHD2 Polymorphism Asp4Glu Is Associated with Hypersensitivity of Erythroid Progenitors to EPO and Upregulation of HIF-1 Regulated Genes Hexokinase (HK1) and Glucose Transporter 1 (SLC2A/GLUT1),

Felipe R Lorenzo, V, M.D., PhD, Sabina Swierczek, PhD, Chad Daniel Huff, PhD, Josef T. Prchal, MD

Blood (2011) 118 (21): 3388.

https://doi.org/10.1182/blood.V118.21.3388.3388

Published: 2011

NARROW

Selective Inhibition of Nuclear Cytoplasmic Transport As a New Treatment Paradigm in Myelofibrosis

Focal Reactivation of Some X-Chromosome Genes in PV and ET Clones

Upregulation of Thrombo-Inflammatory Pathways May Contribute to Increased Thrombotic Risk in Polycythemia Vera and Essential Thrombocythemia

The Effect of IV Iron Therapy on HIF Pathway and HIF Regulated Genes in Elderly Patients with Unexplained Anemia

Reactivation of the X-Chromosome Genes within PV Clone

Calreticulin mutations Are Present in Polyclonal As Well As Clonal ET

Focal Reactivation of X-Chromosome in Female Patients with PV and ET

Effect of a TNFα Blocker and Peginfa on Polycythemia Vera Clonal Hematopoiesis and Suppressed Normal Dormant Hematopoiesis

HIF-Mediated Changes in Erythropoiesis and Gene Expression in Chronic Intermittent Hypoxia Due to Obstructive Sleep Apnea

Autocrine TNF-α Signaling in Hematopoietic Stem Cells Promotes Myeloproliferative Disease Progression through Activation of TNFR2

Ph-Negative Myeloproliferative Neoplasms Exhibit Some Features Of Warburg Effect

Molecular Characterization Of Polycythemia Vera Based On The Relationship Of JAK2 V617F and 9pUPD

Hemopoietic Stem Cells In Polycythemia Vera and Essential Thrombocythemia Have Increased TNF-Alpha That Decreases After Pegylated Interferon-a Therapy, But Not Hydroxyurea, and Correlates With Suppression Of PV and ET Clones

Pegifna Promotes Proliferation and Myeloid Differentiation In Human Hematopoietic Progenitors In Patients With Polycythemia Vera and Essential Thrombocythemia

A Novel EPO Gene Mutation In a Family With Autosomal Dominant Polycythemia

The Number Of Peripheral Blood CD4+CD25+FOXP3+ Regulatory T-Cells Is a Marker Of Response In Patients With JAK2 V617F Positive Myeloproliferative Neoplasms Treated With Pegylated-Interferon-α

A Novel EGLN1/PHD2 High-Frequency Variant in Tibetans Protects Against Hypoxia-Induced Polycythemia.

Salutary Effect of Pegylated Interferona in PV and ET As Evaluated by Quantitation of Pre- JAK2 V617F and JAK2 V617F -Bearing Stem Cells and Granulocytes and Correlation with Circulating Regulatory T Cells and HSC Cell Cycle Status

Whole Exome Sequencing of Polycythemia Vera Reveals Novel Recurrent Somatic and Germline Variation

The Tibetan PHD2 Polymorphism Asp4Glu Is Associated with Hypersensitivity of Erythroid Progenitors to EPO and Upregulation of HIF-1 Regulated Genes Hexokinase (HK1) and Glucose Transporter 1 (SLC2A/GLUT1),

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American Society of Hematology

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American Society of Hematology

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