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Journal Articles

Modulation of Extravascular Binding of Recombinant Factor IX Impacts Hemostatic Efficacy in Mouse Models

Steffi Knoll Machado, Hendrik Peil, Timo Kraushaar, Philipp Claar, Marcel Mischnik, Eva Herzog, Michael Bacher, Marc Wolfgang Nolte, Maximilian Bielohuby, Sabine Pestel, Padmapriya Ponnuswamy
Journal: Blood
Blood (2022) 140 (Supplement 1): 2701–2702.
https://doi.org/10.1182/blood-2022-168756
Published: 2022
Journal Articles

A Quantitative Systems Pharmacology (QSP) Model to Compare the Non-Clinical Biodistribution and Efficacy between Recombinant Factor IX (rIX) Therapies

Sabine Pestel, Douglas Chung, Alireza Rezvani-Sharif, Ineke Muir, Sivarmurthy Krupa, Markus Brechmann, Anne Verhagen, Steve Dower, Piet H. van der Graaf, Eva Herzog, Oliver Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 4240.
https://doi.org/10.1182/blood-2021-145878
Published: 2021
Journal Articles

Pharmacokinetics and Pharmacodynamics of Recombinant FIX Variants in the FIX Knockout Mouse Tail Clip Bleeding Model

Sabine Pestel, Hendrik Peil, Steffi Knoll Machado, Philipp Claar, Elmar Raquet, Padmapriya Ponnuswamy, Marcel Mischnik, Oliver Ghobrial, Eva Herzog
Journal: Blood
Blood (2021) 138 (Supplement 1): 3180.
https://doi.org/10.1182/blood-2021-147819
Published: 2021
Journal Articles

Pharmacokinetic Properties of Different rFVIII Products in Rabbits, Rats and FVIII Ko Mice

Sabine Pestel, DVM, Philipp Claar, Dr rer nat, Jochen Müller-Cohrs, Dr rer nat, Elmar Raquet, Hendrik Peil, Thomas Weimer, Dr rer nat, Eva Herzog, PhD
Journal: Blood
Blood (2015) 126 (23): 1078.
https://doi.org/10.1182/blood.V126.23.1078.1078
Published: 2015