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Samuel Gusscott
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Journal Articles

MYCN Is Required in Immature T-ALL and Bears Epigenetic Marks Associated with Cell Identity

Gabriela Cristina Segat, Ann Chong Sun, Alice C Zhu, Marissa Foo, Claudia V Barreto Rodriguez, Rachel Wong, Samuel Gusscott, Martin Hirst, Andrew P. Weng
Journal: Blood
Blood (2022) 140 (Supplement 1): 8752–8753.
https://doi.org/10.1182/blood-2022-167375
Published: 2022
Journal Articles

DNMT3A Limits Myeloid Signaling Responses in Committed T Cells during Normal and Leukemic Development

Rachel Wong, Samuel Gusscott, Gabriela Cristina Segat, Annaick Carles, Reanne Bowlby, Martin Hirst, Andrew P. Weng
Journal: Blood
Blood (2022) 140 (Supplement 1): 5914.
https://doi.org/10.1182/blood-2022-171228
Published: 2022
Journal Articles

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Manabu Kusakabe, MD PhD, Ann Chong Sun, Kateryna Tyshchenko, Rachel Wong, Aastha Nanda, Claire Shanna, Samuel Gusscott, PhD, Elizabeth Chavez, Alireza Lorzadeh, Alice Zhu, Ainsleigh Hill, Stacy Hung, Scott Brown, Artem Babaian, Xuehai Wang, PhD, Robert Holt, PhD, Christian Steidl, MD, Aly Karsan, MD, R. Keith Humphries, MD PhD, Connie J. Eaves, PhD, Martin Hirst, PhD, Andrew P. Weng, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1322.
https://doi.org/10.1182/blood-2018-99-120120
Published: 2018
Journal Articles

High-Level IGF1R Expression Is Required for Leukemia Stem Cell Activity In T-ALL and Is Supported by Notch Signaling.

Hind Medyouf, PhD, Samuel Gusscott, Carol Wai, Oksana Nemirovsky, Vincenzo Giambra, PhD, Joan M Carboni, PhD, Marco Gottardis, PhD, Francoise Pflumio, PhD, Michael Pollak, MD, Martin Holzenberger, MD, PhD, Andrew P Weng, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3649.
https://doi.org/10.1182/blood.V116.21.3649.3649
Published: 2010
Journal Articles

Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss

Hind Medyouf, Xiuhua Gao, Florence Armstrong, Samuel Gusscott, Qing Liu, Amanda Larson Gedman, Larry H. Matherly, Kirk R. Schultz, Francoise Pflumio, Mingjian James You, Andrew P. Weng
Journal: Blood
Blood (2010) 115 (6): 1175–1184.
https://doi.org/10.1182/blood-2009-04-214718
Published: 2010
Includes: Supplemental data
Journal Articles

Acute T-Cell Leukemias Remain Dependent On Notch Signaling Despite PTEN and INK4A/ARF Loss.

Hind Medyouf, Xiuhua Gao, Florence Armstrong, Samuel Gusscott, Qing Liu, BS, Amanda Larson Gedman, Larry Matherly, PhD, Kirk R. Schultz, MD, Francoise Pflumio, PhD, M. James You, MD, PhD, Andrew P. Weng, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 8.
https://doi.org/10.1182/blood.V114.22.8.8
Published: 2009
Journal Articles

IGF Signaling Is Critical for Growth and Survival of T-Cell Acute Lymphoblastic Leukemia Cells and Is Potentiated by Notch Upregulation of IGF1R

Hind Medyouf, PhD, Samuel Gusscott, Carol Wai, Marcus Leung, Florence Armstrong, PhD, Francoise Pflumio, PhD, Michael Pollak, MD, Andrew P. Weng, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3811.
https://doi.org/10.1182/blood.V112.11.3811.3811
Published: 2008