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Journal Articles

Myelodysplastic Syndromes with 20q Deletion: Incidence, Prognostic Value and Impact on Response to Azacitidine of ASXL1 Chromosomal Deletion and Genetic Mutations

Iván Martín, PhD, Eva Villamón, PhD, Rosario Abellán, PhD, Maria Jose Calasanz, PhD BSc, Aroa Irigoyen, PhD, Guillermo F Sanz, MD PhD, Esperanza Such, PhD, Elvira Mora Casterá, MD, Míriam Gutiérrez, PhD, Rosa Collado, MD, Míriam Vara, PhD, Laura Blanco, MD, Itziar Oiartzabal, MD, Sara Álvarez, PhD, Teresa Bernal del Castillo, MD PhD, Isabel Granada, PhD, Blanca Xicoy, MD, Lurdes Zamora, PhD, Andres Jerez, MDPhD, Raquel Fernández, PhD, Marisa Calabuig, MD, Francisca García, Alejandro Sanz, MD, Rosana Díez, MD, Ángela Gil, MD, Raquel de Paz, MD, Francisca López, MD, Teresa González, MD, Carlos Solano, MD PhD, Mar Tormo, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-139588
Published: 2020
Journal Articles

HDAC Inhibitors As Novel Targeted Therapies for NUP98-HOXA9 AML Patients

Ana Rio-Machin, BSc, MSc, PhD, Gonzalo Gomez-Lopez, BSc, PhD, Alba Maiques-Diaz, BSc, MSc, PhD, Sara Alvarez, MD PhD, Maria Jose Calasanz, BSc, PhD, Jude Fitzgibbon, Juan C Cigudosa, BSc, PhD
Journal: Blood
Blood (2016) 128 (22): 2685.
https://doi.org/10.1182/blood.V128.22.2685.2685
Published: 2016
Journal Articles

Myelodysplastic Syndromes with I(17)(q10) and Prognostic Implications of Mutations of TP53 and SETBP1

Vera Adema, PhDstudent, Larrayoz Maria Jose, Calasanz Maria Jose, PhD, Laura Palomo, PhDstudent, Ana Patiño-Garcia, MD PhD, Xabier Aguirre, PhD, Jesús María Hernández-Rivas, MD PhD, Eva Lumbreras, Ismael Buno, PhD, Carolina Martínez-Laperche, PhD, Mar Mallo, PhD, Olga Garcia, Paula Gomez-Marzo, Sara Alvarez, MD PhD, Beatriz Blazquez, Jose Cervera, MD, Elisa Luño, Alberto Valiente, Teresa Vallespi, MD PhD, Ana Vicente, Leonor Arenillas, MD, Rosa Collado, PhD, Jaime Perez-Oteyza, Francesc Sole, PhD
Journal: Blood
Blood (2014) 124 (21): 1910.
https://doi.org/10.1182/blood.V124.21.1910.1910
Published: 2014
Journal Articles

Clonal Evolution in Chronic Myeloid Leukemia Progression Revelead by Whole-Exome Sequencing

Juliane Menezes, Francesco Acquadro, Gonzalo Gómez López, phD, Sara Alvarez, MD, PhD, Mercedes Trujillo, Juan García-Talavera, David G. Pisano, Juan Cigudosa, phD
Journal: Blood
Blood (2012) 120 (21): 1415.
https://doi.org/10.1182/blood.V120.21.1415.1415
Published: 2012
Journal Articles

Chromatin Modifications Induced by the AML1/ETO Fusion Protein Reversibly Silence Its Genomic Targets Through AML1 and Sp1 Binding Motifs

Alba Maiques-Díaz, Fu-Sheng Chou, MD, PhD, Mark Wunderlich, MS, Gonzalo Gómez López, phD, Filipe V. Jacinto, phD, Sandra Rodriguez-Perales, phD, María José Larrayoz, phD, María José Calasanz, phD, James C. Mulloy, PhD, Juan Cigudosa, phD, Sara Alvarez, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2422.
https://doi.org/10.1182/blood.V118.21.2422.2422
Published: 2011
Journal Articles

Epigenomic Analysis of Acute Myeloid Leukemia Identifies Specific Patterns and Markes with Clinical and Biological Relevance.

Sara Alvarez, MD, PhD, Javier Suela, PhD, Ana Valencia, MD, Agustin Fernandez, PhD, Mark Wunderlich, MS, Xabier Agirre, PhD, Felipe Prosper, MD, Jose Ignacio Martin-Subero, PhD, Alba Maiques, MSc, Francesco Acquadro, MSc, Sandra Rodriguez-Perales, PhD, Maria J. Calasanz, PhD, Jose Roman-Gomez, MD, Reiner Siebert, MD, PhD, James C. Mulloy, PhD, José Cervera, MD, PhD, Miguel A. Sanz, MD, PhD, Manel Esteller, MD, PhD, Juan C Cigudosa, PhD
Journal: Blood
Blood (2009) 114 (22): 2394.
https://doi.org/10.1182/blood.V114.22.2394.2394
Published: 2009
Journal Articles

Immortalization of Human HSPC by a Self-Renewal Signal Coupled with Telomere Maintenance.

Junping Wei, MD, PhD, Mark Wunderlich, Ondrej Krejci, MD PhD, Sara Alvarez, PhD, Juan Cigudosa, PhD, James C. Mulloy, PhD
Journal: Blood
Blood (2006) 108 (11): 2547.
https://doi.org/10.1182/blood.V108.11.2547.2547
Published: 2006
Journal Articles

Leukemic Transformation of Primary Human CD34+ Progenitor Cells by MLL-AF9 Recapitulates the Phenotype and Gene Expression Profile of MLL Rearranged AML.

James C. Mulloy, PhD, Junping Wei, MD PhD, Catherine Rettig, Mark Wunderlich, Sara Alvarez, PhD, Juan Cigudosa, PhD, Michael Jansen, MD, Jorge F. DiMartino, MD PhD
Journal: Blood
Blood (2006) 108 (11): 2210.
https://doi.org/10.1182/blood.V108.11.2210.2210
Published: 2006
Journal Articles

Molecular Karyotyping by High Resolution Arrray CGH Uncovers New Deleted and Amplified Genomic Regions That Contain Genes of Biological Interest in Multiple Myeloma Cells.

Cristina Largo, MSc, Sara Alvarez, MD, PhD, David Blesa, PhD, Felipe Prosper, MD, PhD, M. Jose Calasanz, PhD, Juan Cigudosa, PhD
Journal: Blood
Blood (2005) 106 (11): 1540.
https://doi.org/10.1182/blood.V106.11.1540.1540
Published: 2005
Journal Articles

Identification of Candidate Oncogenes in Acute Megakaryoblastic Leukemias with Gain of Chromosome 19.

Sara Alvarez, MD, PhD, Cristina Largo, BSc, David Blesa, PhD, Alfonso Gomez-Pineda, MD, M. Carmen Martin, BSc, Donal MacGrogan, PhD, Jose F. Garcia, BSc, Giovanna Roncador, PhD, Javier Benitez, PhD, Stephen D. Nimer, MD, Juan C. Cigudosa, PhD
Journal: Blood
Blood (2004) 104 (11): 2023.
https://doi.org/10.1182/blood.V104.11.2023.2023
Published: 2004
Journal Articles

Chromosome 19 abnormalities are commonly seen in AML, M7

Stephen D. Nimer, Donal MacGrogan, Suresh Jhanwar, Sara Alvarez
Journal: Blood
Blood (2002) 100 (10): 3838.
https://doi.org/10.1182/blood-2002-07-2225
Published: 2002
Journal Articles

Cytogenetic characterization reveals that the SAM-1 erythroid cell line is derived from K-562 cells

Sara Alvarez, Donal MacGrogan, Sandra Rodriguez-Perales, Angel Martinez-Ramirez, Miguel Urioste, Javier Benitez, Stephen D. Nimer, Juan C. Cigudosa
Journal: Blood
Blood (2002) 100 (9): 3435.
https://doi.org/10.1182/blood-2002-07-2328
Published: 2002