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Journal Articles

Chronic active Epstein-Barr virus disease originates from infected hematopoietic stem cells

Jingshi Wang, Min Su, Na Wei, Huanyu Yan, Jia Zhang, Yi Gong, Lin Wu, Dina Suolitiken, Yubo Pi, Deli Song, Leilei Chen, Huan Liu, Shuo Yang, Xi Wang, Zhao Wang

Blood (2024) 143 (1): 32–41.

https://doi.org/10.1182/blood.2023021074

Published: 2024

Includes: Supplemental data

Journal Articles

Investigations of Redox Resistance in Aggressive Lymphomas with Cholesterol Modulating Lipid Nanoparticles

Meiying Yang, Jonathan Scott Rink, Shuo Yang, Eva Yang, Kaylin Marie McMahon, Colby Shad Thaxton, Leo I. Gordon, Adam Yuh Lin

Blood (2022) 140 (Supplement 1): 5993–5994.

https://doi.org/10.1182/blood-2022-168394

Published: 2022

Journal Articles

ANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells

Shuo Yang, Xiao-Na Zhu, Hui-Lin Zhang, Qian Yang, Yu-Sheng Wei, Di Zhu, Meng-Di Liu, Shao-Ming Shen, Li Xia, Ping He, Meng-Kai Ge, Yi-Lian Pan, Meng Zhao, Ying-Li Wu, Jun-Ke Zheng, Guo-Qiang Chen, Yun Yu

Blood (2021) 138 (24): 2485–2498.

https://doi.org/10.1182/blood.2020010400

Published: 2021

Includes: Supplemental data

Journal Articles

Bio-Inspired Functional Lipoprotein-like Nanoparticles (Flip-NPs) Cause Cholesterol Starvation and Ferroptosis in B-Cell Lymphomas: Studies in Cell Lines, Xenograft Models and Primary Patient Samples

Jonathan Rink, PhD, Adam Yuh Lin, MD PhD, Shuo Yang, PhD, Amir Behdad, MD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD

Blood (2019) 134 (Supplement_1): 2857.

https://doi.org/10.1182/blood-2019-127805

Published: 2019

Journal Articles

Inhibition of Pro-Survival Pathways in DLBCL Cells By Functional Lipoprotein-like Nanoparticles

Jonathan Rink, PhD, Shuo Yang, PhD, Osman Cen, PhD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD

Blood (2018) 132 (Supplement 1): 1668.

https://doi.org/10.1182/blood-2018-99-119122

Published: 2018

Journal Articles

Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled By Functional Lipoprotein Nanoparticles and the B Cell Receptor Inhibitor Ibrutinib: A Therapeutic Strategy Dependent on Cell of Origin (COO)

Jonathan Rink, PhD, Osman Cen, PhD, Kaylin Marie McMahon, PhD, Sol Misener, BS, Shuo Yang, PhD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD

Blood (2017) 130 (Supplement 1): 576.

https://doi.org/10.1182/blood.V130.Suppl_1.576.576

Published: 2017

Journal Articles

High Density Lipoprotein-like Nanoparticles Synergize with Akt and Btk Inhibitors to Induce Cell Death in Diffuse Large B Cell Lymphomas

Jonathan Scott Rink, PhD, Sol Misener, Osman Cen, PhD, Shuo Yang, Leo I. Gordon, MD, Colby Shad Thaxton, MD, PhD

Blood (2016) 128 (22): 3022.

https://doi.org/10.1182/blood.V128.22.3022.3022

Published: 2016

Journal Articles

Synthetic High-Density Lipoprotein-like Nanoparticles (HDL NP) Cause Apoptosis and Enhance Killing By B-Cell Receptor and BCL-2 Inhibitors in Chronic Lymphocytic Leukemia (CLL)

Kaylin Marie McMahon, Cristina Scielzo, Lydia Scarfo, Pamela Ranghetti, Shuo Yang, Leo I. Gordon, MD, Frank Giles, MDMB, Colby Shad Thaxton, MD PhD, Paolo Ghia, MD PhD

Blood (2015) 126 (23): 2949.

https://doi.org/10.1182/blood.V126.23.2949.2949

Published: 2015

Journal Articles

Scavenger Receptor Type B1 Is Essential for High Density Lipoprotein Nanoparticle Induced B-Cell Lymphoma Cell Death

Jonathan Scott Rink, PhD, Shuo Yang, Osman Cen, Fei Ying, Young Kwang Chae, MD MPH, Denise Scholtens, Jonathan Moreira, MD, Amy Chadburn, MD, Leo I. Gordon, MD, Colby Shad Thaxton

Blood (2015) 126 (23): 2756.

https://doi.org/10.1182/blood.V126.23.2756.2756

Published: 2015

Journal Articles

Foxo 3a Signaling Mediates Apoptosis in Lymphoma Cells By the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographis Paniculata

Shuo Yang, Bo Ding, Fei Ying, Jana Svetlichnaya, Austin Tom, Sheila Prachand, Yanzhuang Wang, Leo I Gordon, MD FACP

Blood (2015) 126 (23): 2760.

https://doi.org/10.1182/blood.V126.23.2760.2760

Published: 2015

Journal Articles

A Novel Therapy Of HLA-Mismatched Sibling Donor Combined With Third-Party Single Cord Blood Cell Transplantation In Patients With Hematologic MalignanciesÂFimproved Outcome Compared To Conventional Transplantation

Aining Sun, Shuo Yang, Jun Wang, Xiao Ma, Weiyang Li, Xiaohui Hu, Huiying Qiu, Wu Depei

Blood (2013) 122 (21): 2088.

https://doi.org/10.1182/blood.V122.21.2088.2088

Published: 2013

Journal Articles

Biomimetic Synthetic High Density Lipoprotein Nanostructures Target the SR-B1 Receptor and Differentially Manipulate Cellular Cholesterol Flux in Lymphoma Cells: A Novel Treatment Paradigm

Shuo Yang, PhD, Marina G Damiano, BS, Heng Zhang, PhD, Sushant Tripathy, BS, Andrey Ugolkov, MD, PhD, Amareshwar T.K. Singh, PhD, Andrea Luthi, BS, Sandeep S. Dave, MD, MS, Shad Thaxton, MD, PhD, Leo I. Gordon, MD

Blood (2012) 120 (21): 157.

https://doi.org/10.1182/blood.V120.21.157.157

Published: 2012

Journal Articles

The Diterpenoid Lactone Andrographolide Induces Reactive Oxygen Species (ROS) Dependent Apoptosis in ATRA Sensitive and Resistant APL Cell Lines.

Shuo Yang, PhD, Jessica K. Altman, MD, Sheila Prachand, MS, Austin Tom, BS, Bo Ding, BS, Brent Wu, Leonidas C. Platanias, MD, PhD, Leo I. Gordon, MD

Blood (2012) 120 (21): 2446.

https://doi.org/10.1182/blood.V120.21.2446.2446

Published: 2012

Journal Articles

Hypoxia Inducible Factor 1á (HIF-1á) Regulates CD20 Expression in Lymphoma Cells: Possible Implications for Rituximab Based Therapy in Diffuse Large B Cell Lymphoma (DLBCL).

Sairah Ahmed, MD, Andrew M. Evens, DO, MSc, Savita Bhalla, PhD, Amareshwar Singh, PhD, Crystal James, Shuo Yang, PhD, Sheila Prachand, Danijela Dokic, MD, Randy D. Gascoyne, MD, Jane N. Winter, MD, Paul T Schumacker, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 1698.

https://doi.org/10.1182/blood.V114.22.1698.1698

Published: 2009

Journal Articles

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

Savita Bhalla, PhD, Leo I. Gordon, MD, Amareshwar Singh, PhD, Sheila Prachand, M.S., Shuo Yang, PhD, Jane N. Winter, MD, Dongsheng Guo, PhD, Thomas O'Halloran, PhD, Leonidas C Platanias, Andrew M. Evens, DO, MSc

Blood (2009) 114 (22): 2708.

https://doi.org/10.1182/blood.V114.22.2708.2708

Published: 2009

Journal Articles

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

Shuo Yang, PhD, Andrew M Evens, DO, MSc, Savita Bhalla, PhD, Sheila Prachand, M.S., Amareshwar Singh, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 2710.

https://doi.org/10.1182/blood.V114.22.2710.2710

Published: 2009

Journal Articles

All Trans Retinoic Acid Nanodisks Enhance Retinoic Acid Receptor-Mediated Apoptosis and Cell Cycle Arrest in Mantle Cell Lymphoma.

Amareshwar Singh, PhD, Andrew M Evens, DO, MSc, Reilly Anderson, BS, Jennifer Beckstead, MS, Natesan Sankar, PhD, Savita Bhalla, PhD, Shuo Yang, PhD, Trudy Forte, PhD, Robert Ryan, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 3722.

https://doi.org/10.1182/blood.V114.22.3722.3722

Published: 2009

Journal Articles

The Diterpenoid Lactone Andrographolide (ANDRO) Stimulates Autophagy and Induces Reactive Oxygen Species (ROS)-Dependent Apoptosis in Lymphoma Cell Lines

Shuo Yang, PhD, Andrew M. Evens, DO, MS, Sheila Prachand, MS, Leo I. Gordon, MD

Blood (2008) 112 (11): 4991.

https://doi.org/10.1182/blood.V112.11.4991.4991

Published: 2008

NARROW

Chronic active Epstein-Barr virus disease originates from infected hematopoietic stem cells

Investigations of Redox Resistance in Aggressive Lymphomas with Cholesterol Modulating Lipid Nanoparticles

ANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells

Bio-Inspired Functional Lipoprotein-like Nanoparticles (Flip-NPs) Cause Cholesterol Starvation and Ferroptosis in B-Cell Lymphomas: Studies in Cell Lines, Xenograft Models and Primary Patient Samples

Inhibition of Pro-Survival Pathways in DLBCL Cells By Functional Lipoprotein-like Nanoparticles

Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled By Functional Lipoprotein Nanoparticles and the B Cell Receptor Inhibitor Ibrutinib: A Therapeutic Strategy Dependent on Cell of Origin (COO)

High Density Lipoprotein-like Nanoparticles Synergize with Akt and Btk Inhibitors to Induce Cell Death in Diffuse Large B Cell Lymphomas

Synthetic High-Density Lipoprotein-like Nanoparticles (HDL NP) Cause Apoptosis and Enhance Killing By B-Cell Receptor and BCL-2 Inhibitors in Chronic Lymphocytic Leukemia (CLL)

Scavenger Receptor Type B1 Is Essential for High Density Lipoprotein Nanoparticle Induced B-Cell Lymphoma Cell Death

Foxo 3a Signaling Mediates Apoptosis in Lymphoma Cells By the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographis Paniculata

A Novel Therapy Of HLA-Mismatched Sibling Donor Combined With Third-Party Single Cord Blood Cell Transplantation In Patients With Hematologic MalignanciesÂFimproved Outcome Compared To Conventional Transplantation

Biomimetic Synthetic High Density Lipoprotein Nanostructures Target the SR-B1 Receptor and Differentially Manipulate Cellular Cholesterol Flux in Lymphoma Cells: A Novel Treatment Paradigm

The Diterpenoid Lactone Andrographolide Induces Reactive Oxygen Species (ROS) Dependent Apoptosis in ATRA Sensitive and Resistant APL Cell Lines.

Hypoxia Inducible Factor 1á (HIF-1á) Regulates CD20 Expression in Lymphoma Cells: Possible Implications for Rituximab Based Therapy in Diffuse Large B Cell Lymphoma (DLBCL).

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

All Trans Retinoic Acid Nanodisks Enhance Retinoic Acid Receptor-Mediated Apoptosis and Cell Cycle Arrest in Mantle Cell Lymphoma.

The Diterpenoid Lactone Andrographolide (ANDRO) Stimulates Autophagy and Induces Reactive Oxygen Species (ROS)-Dependent Apoptosis in Lymphoma Cell Lines

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American Society of Hematology

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American Society of Hematology

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