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Journal Articles

Pre-Clinical Development of a Highly Efficient TALEN ® -Based Correction of the β-Globin Gene in Patient-Derived Hematopoietic Stem and Progenitor Cells (HSPCs) to Treat Sickle Cell Disease

Arianna Moiani, Patrick Hong, Gil Letort, Sabrina Lizot, Alexa Chirinos, Sonal Temburni-Blake, Sara Nik, Louisa Mayer, Sophie Leduc, Noemie Pinard, Chloe Foray, Alex Boyne, Selena Kazancioglu, Giacomo Frati, Tristan Felix, Anne Chalumeau, Annarita Miccio, Mathilde Dusseaux, Agnès Gouble, Mark G. Frattini, Carrie Brownstein, Aymeric Duclert, Cecile Shiffer-Mannoui, Alexandre Juillerat, Philippe Duchateau, Julien Valton
Journal: Blood
Blood (2021) 138 (Supplement 1): 1856.
https://doi.org/10.1182/blood-2021-153549
Published: 2021
Journal Articles

TALEN ® -Based Gene Editing in Hematopoietic Stem Cells

Brian W Busser, PhD, Sonal Temburni, Alex Boyne, Alexandre Juillerat, Laurent Poirot, PhD, Philippe Duchateau
Journal: Blood
Blood (2018) 132 (Supplement 1): 5796.
https://doi.org/10.1182/blood-2018-99-117211
Published: 2018
Journal Articles

Ibrutinib Inhibits Concomitant TLR and BCR- Driven Proliferation of Chronic Lymphocytic Leukemia Cells and Overrides the Supportive Survival-Promoting Effects of Microenvironmental Signals

Sonal Temburni, MS, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Betty Y. Chang, Nicholas Chiorazzi, MD, Rajendra N Damle, PhD
Journal: Blood
Blood (2014) 124 (21): 3310.
https://doi.org/10.1182/blood.V124.21.3310.3310
Published: 2014
Journal Articles

Reciprocal Densities of CXCR4 and CD5 Define Subfractions of Chronic Lymphocytic Leukemia Clones Differing in Phenotype and Response to Environmental Stimuli: Towards a Better Definition of Targetable Components of Leukemic Clones

Rajendra N Damle, PhD, Sonal Temburni, MS, Cristina Sison, PhD, Jaison Jain, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2014) 124 (21): 3322.
https://doi.org/10.1182/blood.V124.21.3322.3322
Published: 2014
Journal Articles

Concomitant, T-Independent TLR9-Mediated and BCR-Mediated Activation Provides Signals For Optimal Telomerase Induction In Chronic Lymphocytic Leukemia Cells Regardless Of IGHV Mutation Status

Rajendra N Damle, PhD, Sonal Temburni, MS, Ryon M. Andersen, B.A., Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, M.D., Kanti R. Rai, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2013) 122 (21): 4142.
https://doi.org/10.1182/blood.V122.21.4142.4142
Published: 2013
Journal Articles

T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients

Rajendra N. Damle, Sonal Temburni, Taraneh Banapour, Santanu Paul, Patricia K. A. Mongini, Steven L. Allen, Jonathan E. Kolitz, Kanti R. Rai, Nicholas Chiorazzi
Journal: Blood
Blood (2012) 120 (12): 2438–2449.
https://doi.org/10.1182/blood-2012-02-409110
Published: 2012
Journal Articles

TLR-9 and B-Cell Antigen Receptor Triggering of Primary B Cells From Mantle Cell Lymphoma Induce Cell Proliferation and Telomerase Activity,

Sonal Temburni, MS, Ryon M. Andersen, B.A., Steven L. Allen, M.D., Jaqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D., Rajendra N Damle, PhD
Journal: Blood
Blood (2011) 118 (21): 3690.
https://doi.org/10.1182/blood.V118.21.3690.3690
Published: 2011
Journal Articles

Longitudinal Analyses of CXCR4 dim CD5 br CD19 + Fractions of Chronic Lymphocytic Leukemia Clones Reveal Features Consistent with a Source of Clonal Heterogeneity

Rajendra N Damle, PhD, Carlo Calissano, MD, Sonal Temburni, MS, Ryon M. Andersen, B.A., Steven L. Allen, M.D., Jonathan E. Kolitz, MD, Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.
Journal: Blood
Blood (2011) 118 (21): 804.
https://doi.org/10.1182/blood.V118.21.804.804
Published: 2011
Journal Articles

CCR4: TARC Interaction Provides Supplementary Pro-Survival and Proliferative Signals to Chronic Lymphocytic Leukemia Cells.

Rajendra N Damle, PhD, Sonal Temburni, Matthew Kaufman, MD, Jonathan E. Kolitz, MD, Steven L. Allen, Fabio Malavasi, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2009) 114 (22): 2327.
https://doi.org/10.1182/blood.V114.22.2327.2327
Published: 2009
Journal Articles

Efficiency of BCR: Anti-BCR Interaction Dictates Cellular Outcomes of Signaling in Chronic Lymphocytic Leukemia Cells

Rajendra Damle, Sonal Temburni, Tara Schaaf, Santanu Paul, Patricia Mongini, Steven L. Allen, Matthew Kaufman, Kanti Rai, Nicholas Chiorazzi
Journal: Blood
Blood (2008) 112 (11): 3122.
https://doi.org/10.1182/blood.V112.11.3122.3122
Published: 2008
Journal Articles

CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells

Rajendra N. Damle, Sonal Temburni, Carlo Calissano, Sophia Yancopoulos, Taraneh Banapour, Cristina Sison, Steven L. Allen, Kanti R. Rai, Nicholas Chiorazzi
Journal: Blood
Blood (2007) 110 (9): 3352–3359.
https://doi.org/10.1182/blood-2007-04-083832
Published: 2007
Journal Articles

Remarkable Differences in Cellular Activation State and Migratory and Proliferative Potential among Clonal Cells Derived from Different Tissues of Chronic Lymphocytic Leukemia Patients.

Rajendra N. Damle, PhD, Taraneh Banapour, BS, Sonal Temburni, BS, Tarun Wasil, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Barbara Sherry, PhD, Kanti R. Rai, MBBS, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2006) 108 (11): 2817.
https://doi.org/10.1182/blood.V108.11.2817.2817
Published: 2006