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Journal Articles

High-Dose Melphalan Significantly Increases Mutational Burden in Multiple Myeloma Cells at Relapse: Results from a Randomized Study in Multiple Myeloma

Mehmet K. Samur, PhD, Marco Roncador, MD MSc, Anil Aktas-Samur, PhD, Mariateresa Fulciniti, PhD, Abdul Hamid Bazarbachi, MD, Raphael Szalat, Masood A. Shammas, PhD, Adam S Sperling, MD PhD, Paul G. Richardson, MD, Florence Magrangeas, Stephane Minvielle, PhD, Anjan Thakurta, Aurore Perrot, Jill Corre, PharmD, PhD, Philippe Moreau, MD, Kenneth Anderson, MD, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-139014

Published: 2020

Journal Articles

IGLL5-BCL2L1 Rearrangement with Loss of BCL2 Dependency As Mechanism of Venetoclax Resistance in Multiple Myeloma (MM)

Jean-Baptiste Alberge, Sarthak Sinha, BSc, Ranjan Maity, PhD, Arzina Jaffer, Justin Donovan, Madison Kong, Stephane Minvielle, PhD, Paola Neri, MD PhD, Nizar Bahlis, MD

Blood (2019) 134 (Supplement_1): 686.

https://doi.org/10.1182/blood-2019-131981

Published: 2019

Journal Articles

The Landscape of Genome Wide Somatic Alterations Identifies a Good-Risk Group in Newly Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Anil Aktas Samur, PhD, Tessa Han, Marco Roncador, MD MSc, Mariateresa Fulciniti, PhD, Raphael Szalat, Masood A. Shammas, PhD, Jill Corre, PharmD, PhD, Paul G. Richardson, MD, Florence Magrangeas, Stephane Minvielle, PhD, Philippe Moreau, MD, Michel Attal, MD PhD, Anjan Thakurta, Kenneth C. Anderson, MD, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 3055.

https://doi.org/10.1182/blood-2019-128521

Published: 2019

Journal Articles

Dysregulated Mirnas after Uniform Treatment Predict Outcome of Newly-Diagnosed Multiple Myeloma

Tessa Han, Stephane Minvielle, PhD, Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Florence Magrangeas, PhD, Paul G. Richardson, MD, Philippe Moreau, MD, Michel Attal, MD PhD, Kenneth C. Anderson, MD, Hervé Avet-Loiseau, MD PhD, Giovanni Parmigiani, PhD, Mehmet Kemal Samur, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4348.

https://doi.org/10.1182/blood-2019-130343

Published: 2019

Journal Articles

Poor Prognosis Associated with Gains of CCND1 in Mantle Cell Lymphoma Treated By First Line Immuno-Chemotherapy — a Study By the Lysa Group

Blood (2018) 132 (Supplement 1): 4099.

https://doi.org/10.1182/blood-2018-99-113303

Published: 2018

Journal Articles

The Landscape of Structural Variant Signatures in Multiple Myeloma Identifies Distinct Disease Subgroups with Implications for Pathogenesis

Francesco Maura, Daniel Leongamornlert, BS, Nicos Angelopoulos, PhD, Kevin J Dawson, Mehmet Kemal Samur, PhD, Raphael Szalat, MD, Yu-Tzu Tai, PhD, Stephane Minvielle, PhD, Florence Magrangeas, Philippe Moreau, Paolo Corradini, MD, Kenneth C. Anderson, MD, Hervé Avet-Loiseau, MDPhD, Peter J. Campbell, PhD, Nikhil Munshi, MD, Niccolò Bolli

Blood (2018) 132 (Supplement 1): 109.

https://doi.org/10.1182/blood-2018-99-112420

Published: 2018

Journal Articles

Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Chandraditya Chakraborty, PhD, Raphael Szalat, MD, Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Michael A Lopez, Masood A. Shammas, PhD, Paul Richardson, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Philippe Moreau, Michel Attal, Anjan Thakurta, PhD, Kenneth Anderson, MD, Giovanni Parmigiani, Hervé Avet-Loiseau, MDPhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 190.

https://doi.org/10.1182/blood-2018-190

Published: 2018

Journal Articles

Correlations between p16 Protein Expression and Genomic Profile in Mantle Cell Lymphoma and Impact on Survival, a Lyma-Genomic Project Conducted on Behalf of the Lysa Group

Yannick LE Bris, MDPharmD, Danielle Canioni, MD, Barbara Burroni, MD, Anne Moreau, MD, Benoit Tessoulin, MD, Florence Magrangeas, PhD, Marie-Helene Delfau, MD, Catherine Thieblemont, MD, Lucie Oberic, MD, Krimo Bouabdallah, MD, Emmanuel Gyan, MD PhD, David Chiron, PhD, Catherine Pellat-deceunynck, PhD, Mary Callanan, PhD, Stephane Minvielle, PhD, Marie C Bene, PharmSci, PhD, Olivier Hermine, MD PhD, Steven Le Gouill, MD PhD

Blood (2018) 132 (Supplement 1): 2846.

https://doi.org/10.1182/blood-2018-99-113268

Published: 2018

Journal Articles

Deciphering the Chronology of Copy Number Alterations in Multiple Myeloma (MM): What Comes First?

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Stephane Minvielle, PhD, Florence Magrangeas, PhD, Masood A. Shammas, PhD, Mariateresa Fulciniti, PhD, Michel Attal, MD PhD, Philippe Moreau, Kenneth Anderson, MD, Giovanni Parmigiani, Hervé Avet-Loiseau, MD PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 3171.

https://doi.org/10.1182/blood-2018-99-120101

Published: 2018

Journal Articles

A Detailed Alternate Splicing Landscape in Multiple Myeloma with Significant Potential Biological and Clinical Implications

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Stephane Minvielle, PhD, Florence Magrangeas, Mariateresa Fulciniti, PhD, Raphael Szalat, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Michel Attal, Philippe Moreau, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C Munshi, MD

Blood (2016) 128 (22): 356.

https://doi.org/10.1182/blood.V128.22.356.356

Published: 2016

Journal Articles

The Complex Landscape of Rearrangements in Smoldering and Symptomatic Multiple Myeloma Revealed By Whole-Genome Sequencing

Blood (2016) 128 (22): 236.

https://doi.org/10.1182/blood.V128.22.236.236

Published: 2016

Journal Articles

Global Genomic Analysis of Newly Diagnosed t(4 ;14) Multiple Myeloma Reveals a Specific Mutational Spectrum and Identifies PKD2 As a Potential Therapeutic Target

Xiu Ly Song, Raphaël Szalat, MD, Alexis Talbot, MD, HaiVu Nguyen, PhD, Mehmet K. Samur, PhD, David Mosen-Ansorena, PhD, Nikhil C. Munshi, MD, Stephane Minvielle, PhD, Herve Avet Loiseau, MD PhD, Wendy Cuccuini, MD PhD, Jean-Paul Fermand, MD, Bertrand Arnulf, MD PhD, Jean-Christophe Bories

Blood (2016) 128 (22): 4462.

https://doi.org/10.1182/blood.V128.22.4462.4462

Published: 2016

Journal Articles

RNA-Seq De Novo Assembly of Clonal Immunoglobulin Rearrangements Identifies Interesting Biology and Uncovers Prognostic Features in Multiple Myeloma

David Mosen-Ansorena, PhD, Rachael Bashford-Rogers, PhD, Niccolo Bolli, MD, Stephane Minvielle, PhD, Florence Magrangeas, Kenneth C Anderson, MD, Herve Avet-Loiseau, MD PhD, Giovanni Parmigiani, PhD, Nikhil C Munshi, MD

Blood (2016) 128 (22): 195.

https://doi.org/10.1182/blood.V128.22.195.195

Published: 2016

Journal Articles

in Multiple Myeloma, High-Risk Features Are Modulated By Other Chromosomal changes : A Large Snparray IFM Study

Jill Corre, PharmD, PhD, Benjamin Hebraud, MD, Florence Magrangeas, PhD, Valérie Lauwers-Cances, MD, Marie-Lorraine Chretien, MD, Stephane Minvielle, PhD, Hervé Avet-Loiseau

Blood (2014) 124 (21): 641.

https://doi.org/10.1182/blood.V124.21.641.641

Published: 2014

Journal Articles

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

Blood (2014) 124 (21): 4714.

https://doi.org/10.1182/blood.V124.21.4714.4714

Published: 2014

Journal Articles

Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells

Weihua Song, MD, Chaolin Zhang, PhD, Yiguo Hu, PhD, Maria Gkotzamanidou, MD, Parantu Shah, PhD, Weisong Shan, MD PhD, Guang Yang, PhD, Samir B. Amin, MBBS, Yu-Tzu Tai, PhD, Yi Li, PhD, Adam Sperling, MD, PhD, Naim Rashid, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Hervé Avet-Loiseau, MD, PhD, Kenneth C. Anderson, MD, Cheng Li, PhD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 3085.

https://doi.org/10.1182/blood.V122.21.3085.3085

Published: 2013

Journal Articles

Low Level Of NF-Kb Activity Is Associated With Higher Response Rate To Bortezomib-Based Induction Therapy In Patients With Newly Diagnosed Multiple Myeloma

Florence Magrangeas, PhD, Philippe Moreau, MD, Loic Campion, MD, Herve Avet-Loiseau, MD, Catherine Guérin, Wilfried Gouraud, Gérald Marit, MD, Michel Attal, MD, Denis Caillot, MD, Thierry Facon, MD, Cyrille Hulin, MD, Lotfi Benboubker, MD, Brigitte Pegourie, MD, Stephane Minvielle, PhD

Blood (2013) 122 (21): 3106.

https://doi.org/10.1182/blood.V122.21.3106.3106

Published: 2013

Journal Articles

Cereblon (CRBN) Splicing Could Influence Response To IMiDs : A New PCR Strategy to Easily Detect and Semi-Quantify Loss Of The IMiDs Binding Domain

Blood (2013) 122 (21): 3107.

https://doi.org/10.1182/blood.V122.21.3107.3107

Published: 2013

Journal Articles

Functional and Molecular Impact Of Dp1-Dependent Alternate Splicing In Multiple Myeloma

Mariateresa Fulciniti, PhD, Manoj Bashin, Ph.D, Mehmet Kemal Samur, PhD, Rajya Bandi, Parantu K Shah, PhD, Antonia Cagnetta, MD, Cheng Li, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Herve Avet-Loiseau, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 1845.

https://doi.org/10.1182/blood.V122.21.1845.1845

Published: 2013

Journal Articles

Non Homologous End Joining, a Marker Of Genomic Instability Is Elevated In Multiple Myeloma: A New Prognostic Factor

Teresa Calimeri, MD, Mehmet Kemal Samur, PhD, Nicola Amodio, PhD, Michele Cea, MD, Antonia Cagnetta, MD, Mariateresa Fulciniti, PhD, Sophia Adamia, PhD, Marco Rossi, MD, Yu-Tzu Tai, PhD, Fortunato Morabito, MD, Abdel Kareem Azab, BPharm, PhD, Stephane Minvielle, PhD, Herve Avet-Loiseau, MD, Cheng Li, PhD, Jean-Bernard Lazaro, PhD, Kenneth C. Anderson, Masood A. Shammas, Pierfrancesco Tassone, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 124.

https://doi.org/10.1182/blood.V122.21.124.124

Published: 2013

NARROW

High-Dose Melphalan Significantly Increases Mutational Burden in Multiple Myeloma Cells at Relapse: Results from a Randomized Study in Multiple Myeloma

IGLL5-BCL2L1 Rearrangement with Loss of BCL2 Dependency As Mechanism of Venetoclax Resistance in Multiple Myeloma (MM)

The Landscape of Genome Wide Somatic Alterations Identifies a Good-Risk Group in Newly Diagnosed Multiple Myeloma

Dysregulated Mirnas after Uniform Treatment Predict Outcome of Newly-Diagnosed Multiple Myeloma

Poor Prognosis Associated with Gains of CCND1 in Mantle Cell Lymphoma Treated By First Line Immuno-Chemotherapy — a Study By the Lysa Group

The Landscape of Structural Variant Signatures in Multiple Myeloma Identifies Distinct Disease Subgroups with Implications for Pathogenesis

Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

Correlations between p16 Protein Expression and Genomic Profile in Mantle Cell Lymphoma and Impact on Survival, a Lyma-Genomic Project Conducted on Behalf of the Lysa Group

Deciphering the Chronology of Copy Number Alterations in Multiple Myeloma (MM): What Comes First?

A Detailed Alternate Splicing Landscape in Multiple Myeloma with Significant Potential Biological and Clinical Implications

The Complex Landscape of Rearrangements in Smoldering and Symptomatic Multiple Myeloma Revealed By Whole-Genome Sequencing

Global Genomic Analysis of Newly Diagnosed t(4 ;14) Multiple Myeloma Reveals a Specific Mutational Spectrum and Identifies PKD2 As a Potential Therapeutic Target

RNA-Seq De Novo Assembly of Clonal Immunoglobulin Rearrangements Identifies Interesting Biology and Uncovers Prognostic Features in Multiple Myeloma

in Multiple Myeloma, High-Risk Features Are Modulated By Other Chromosomal changes : A Large Snparray IFM Study

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells

Low Level Of NF-Kb Activity Is Associated With Higher Response Rate To Bortezomib-Based Induction Therapy In Patients With Newly Diagnosed Multiple Myeloma

Cereblon (CRBN) Splicing Could Influence Response To IMiDs : A New PCR Strategy to Easily Detect and Semi-Quantify Loss Of The IMiDs Binding Domain

Functional and Molecular Impact Of Dp1-Dependent Alternate Splicing In Multiple Myeloma

Non Homologous End Joining, a Marker Of Genomic Instability Is Elevated In Multiple Myeloma: A New Prognostic Factor

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